Ambien and Benadryl drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Ambien and Benadryl together. This review analyzes the effectiveness and drug interactions between Ambien and Benadryl. It is created by eHealthMe based on reports of 3,827 people who take the same drugs from FDA, and is updated regularly.

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Ambien

Ambien has active ingredients of zolpidem tartrate. It is often used in insomnia. (latest outcomes from Ambien 63,975 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in allergies. (latest outcomes from Benadryl 44,713 users)

On Jan, 27, 2017

3,827 people who take Ambien, Benadryl are studied.


Number of reports submitted per year:

Ambien and Benadryl drug interactions.

Most common drug interactions over time *:

< 1 month:
  • hypotension
  • pyrexia
  • anaemia
  • pneumothorax
  • febrile neutropenia
  • dehydration
  • skin ulcer
  • malaise
  • atrial tachycardia
  • dyspnoea
1 - 6 months:
  • death
  • stevens-johnson syndrome
  • intestinal perforation
  • pyrexia
  • bacteraemia
  • interstitial lung disease
  • oral candidiasis
  • rhinorrhoea
  • small intestinal obstruction
  • thrombocytopenia
6 - 12 months:
  • atrial septal defect
  • asthenia
  • gait disturbance
  • amnesia
  • anger
  • ataxia
  • bradyarrhythmia
  • confusional state
  • depression
  • disturbance in attention
1 - 2 years:
  • dizziness
  • hyponatraemia
  • nausea
  • vomiting
  • atelectasis
  • nephrogenic systemic fibrosis
  • renal failure acute
  • atrial septal defect
  • congenital mitral valve incompetence
  • jaundice neonatal
2 - 5 years:
  • depression
  • balance disorder
  • dysarthria
  • impaired driving ability
  • lacrimation increased
  • ocular hyperaemia
  • road traffic accident
  • somnambulism
  • drug withdrawal convulsions
  • memory impairment
5 - 10 years:
  • pain
  • contusion
  • fall
  • oedema peripheral
  • amnesia
  • arthralgia
  • eating disorder
  • somnambulism
  • somnolence
  • anxiety
10+ years:
  • depression
  • constipation
  • road traffic accident
  • abdominal pain upper
  • amnesia
  • anxiety
  • cellulitis
  • chest injury
  • drug dependence
  • fall
not specified:
  • pain
  • nausea
  • anxiety
  • fatigue
  • dyspnoea
  • headache
  • arthralgia
  • vomiting
  • back pain
  • pyrexia

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • dyspnoea
  • fatigue
  • headache
  • arthralgia
  • vomiting
  • pyrexia
  • insomnia
male:
  • pain
  • nausea
  • fatigue
  • dyspnoea
  • anxiety
  • asthenia
  • pyrexia
  • back pain
  • vomiting
  • diarrhoea

Most common drug interactions by age *:

0-1:
  • cardiac arrest
  • respiratory arrest
  • convulsion
  • poisoning
  • aggression
  • drug toxicity
  • orthostatic hypotension
  • agitation
  • foaming at mouth
  • tardive dyskinesia
2-9:
  • fungal test positive
  • hypokalaemia
  • transfusion reaction
  • bronchiectasis
  • culture positive
  • diarrhoea
  • rash
  • respiratory tract infection fungal
  • restrictive pulmonary disease
  • stem cell transplant
10-19:
  • agitation
  • weight increased
  • convulsion
  • drug abuse
  • headache
  • musculoskeletal stiffness
  • pyrexia
  • suicidal ideation
  • pneumonia
  • vomiting
20-29:
  • insomnia
  • nausea
  • pain
  • anxiety
  • vomiting
  • back pain
  • influenza like illness
  • urinary tract infection
  • headache
  • completed suicide
30-39:
  • pain
  • pyrexia
  • dyspnoea
  • nausea
  • headache
  • abdominal pain
  • completed suicide
  • fatigue
  • depression
  • insomnia
40-49:
  • pain
  • back pain
  • nausea
  • anxiety
  • arthralgia
  • headache
  • pain in extremity
  • diarrhoea
  • fall
  • fatigue
50-59:
  • anxiety
  • pain
  • dyspnoea
  • nausea
  • injury
  • pyrexia
  • arthralgia
  • fatigue
  • insomnia
  • osteonecrosis of jaw
60+:
  • fatigue
  • nausea
  • dyspnoea
  • anxiety
  • fall
  • asthenia
  • pain
  • anaemia
  • back pain
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Ambien and Benadryl?

Interactions between Ambien and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Benadryl and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Ambien (zolpidem tartrate) is often used to treat insomnia. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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