Review: taking Amitriptyline hydrochloride and Amlodipine besylate together


Summary

Drug interactions are reported among people who take Amitriptyline hydrochloride and Amlodipine besylate together. This review analyzes the effectiveness and drug interactions between Amitriptyline hydrochloride and Amlodipine besylate. It is created by eHealthMe based on reports of 1,927 people who take the same drugs from FDA and social media, and is updated regularly.

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Amitriptyline Hydrochloride

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in depression. (latest outcomes from Amitriptyline hydrochloride 6,775 users)

Amlodipine Besylate

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Amlodipine besylate 18,517 users)

On Jul, 29, 2016

1,927 people who take Amitriptyline Hydrochloride, Amlodipine Besylate are studied.


Number of reports submitted per year:

Amitriptyline hydrochloride and Amlodipine besylate drug interactions.

Drug effectiveness over time:

Amitriptyline Hydrochloride:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 0.0% - (0 of 6 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 0.0% - (0 of 4 people)
  • 2 - 5 years: 71.0% - (5 of 7 people)
  • 5 - 10 years: 75.0% - (3 of 4 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 0 people)
Amlodipine Besylate:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 42.0% - (3 of 7 people)
  • 6 - 12 months: 25.0% - (1 of 4 people)
  • 1 - 2 years: 30.0% - (3 of 10 people)
  • 2 - 5 years: 50.0% - (5 of 10 people)
  • 5 - 10 years: 100.0% - (3 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Amitriptyline Hydrochloride:
  • female: 27.0% - (5 of 18 people)
  • male: 50.0% - (7 of 14 people)
Amlodipine Besylate:
  • female: 61.0% - (11 of 18 people)
  • male: 29.0% - (5 of 17 people)

Drug effectiveness by age:

Amitriptyline Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 25.0% - (1 of 4 people)
  • 50-59: 0.0% - (0 of 8 people)
  • 60+: 61.0% - (11 of 18 people)
Amlodipine Besylate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 20.0% - (1 of 5 people)
  • 50-59: 62.0% - (5 of 8 people)
  • 60+: 50.0% - (10 of 20 people)

Most common drug interactions over time *:

< 1 month:
  • asthenia
  • disorientation
  • fatigue
  • amnesia
  • cognitive disorder
  • depression
  • myopathy
  • neuropathy peripheral
  • somnolence
  • blood potassium increased
1 - 6 months:
  • arthralgia
  • irritable bowel syndrome
  • panic attack
  • diarrhoea
  • heart rate increased
  • hypertension
  • abdominal pain upper
  • nausea
  • reflexes abnormal
  • syncope
6 - 12 months:
  • hypertension
  • anxiety
  • cardiac failure congestive
  • cerebrovascular accident
  • coronary artery disease
  • depression
  • dizziness
  • heart rate increased
  • myocardial infarction
  • nausea
1 - 2 years:
  • vertigo positional
  • fatigue
  • abdominal discomfort
  • balance disorder
  • diarrhoea
  • drug eruption
  • dysarthria
  • dysuria
  • fungal infection
  • gastrooesophageal reflux disease
2 - 5 years:
  • depression
  • infection
  • loose tooth
  • osteonecrosis
  • anxiety
  • blood disorder
  • impaired healing
  • cardiac disorder
  • abdominal pain
  • cerebrovascular accident
5 - 10 years:
  • depression
  • myocardial infarction
  • cardiac failure congestive
  • chronic obstructive pulmonary disease
  • constipation
  • hypertension
  • dizziness
  • fall
  • gastrooesophageal reflux disease
  • loss of consciousness
10+ years:
  • dry mouth
  • dry skin
  • renal failure acute
  • swelling in the abdomen
  • swelling of the ankles - feet - legs
  • weight gain
  • anhedonia
  • anxiety
  • atrial fibrillation
  • death
not specified:
  • pain
  • dyspnoea
  • nausea
  • arthralgia
  • fall
  • anxiety
  • cardiac failure congestive
  • chest pain
  • diarrhoea
  • dizziness

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • arthralgia
  • dyspnoea
  • fall
  • anxiety
  • diarrhoea
  • dizziness
  • cardiac failure congestive
  • chest pain
male:
  • pain
  • oedema peripheral
  • dyspnoea
  • fatigue
  • anaemia
  • depression
  • myocardial infarction
  • neuropathy peripheral
  • anxiety
  • cardiac failure congestive

Most common drug interactions by age *:

2-9:
  • hypertension
  • pyrexia
10-19:
  • nephrogenic systemic fibrosis
  • cardiac arrest
  • fibrosis
  • metaplasia
  • mobility decreased
  • muscle contracture
  • myocardial fibrosis
  • pain in extremity
  • pulmonary fibrosis
  • skin induration
20-29:
  • abdominal pain upper
  • pain
  • abdominal pain
  • cholecystitis
  • completed suicide
  • vaginal haemorrhage
  • alanine aminotransferase increased
  • anhedonia
  • anorexia
  • aspartate aminotransferase increased
30-39:
  • pain
  • skin discolouration
  • arthralgia
  • gait disturbance
  • joint range of motion decreased
  • nephrogenic systemic fibrosis
  • pruritus
  • skin burning sensation
  • skin hypertrophy
  • skin swelling
40-49:
  • chest pain
  • back pain
  • anaemia
  • pain
  • anxiety
  • deep vein thrombosis
  • diabetes mellitus
  • injury
  • asthma
  • joint sprain
50-59:
  • pain
  • dizziness
  • anxiety
  • nausea
  • fall
  • hypoaesthesia
  • arthralgia
  • bone disorder
  • vomiting
  • dyspnoea
60+:
  • nausea
  • dyspnoea
  • arthralgia
  • hypertension
  • pain
  • fall
  • diarrhoea
  • irritable bowel syndrome
  • asthenia
  • pneumonia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Amitriptyline hydrochloride (amitriptyline hydrochloride) is often used to treat depression. Amlodipine besylate (amlodipine besylate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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