Amitriptyline hydrochloride and Zanaflex drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Amitriptyline hydrochloride and Zanaflex together. This review analyzes the effectiveness and drug interactions between Amitriptyline hydrochloride and Zanaflex. It is created by eHealthMe based on reports of 1,289 people who take the same drugs from FDA, and is updated regularly.

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Amitriptyline Hydrochloride

Amitriptyline hydrochloride has active ingredients of amitriptyline hydrochloride. It is often used in migraine. (latest outcomes from Amitriptyline hydrochloride 8,443 users)

Zanaflex

Zanaflex has active ingredients of tizanidine hydrochloride. It is often used in muscle spasms. (latest outcomes from Zanaflex 10,449 users)

On Jan, 28, 2017

1,289 people who take Amitriptyline Hydrochloride, Zanaflex are studied.


Number of reports submitted per year:

Amitriptyline hydrochloride and Zanaflex drug interactions.

Most common drug interactions over time *:

< 1 month:
  • nausea
  • headache
  • fatigue
  • pain
  • amnesia
  • dizziness
  • asthenia
  • balance disorder
  • cerebrovascular accident
  • cognitive disorder
1 - 6 months:
  • pain in extremity
  • blindness
  • diabetes mellitus
  • diabetic gastroparesis
  • diabetic ketoacidosis
  • diabetic neuropathy
  • hyperglycaemia
  • hysterectomy
  • loss of consciousness
  • multiple sclerosis relapse
6 - 12 months:
  • tremor
  • anxiety
  • arthralgia
  • cushingoid
  • dehydration
  • drug withdrawal syndrome
  • duodenal ulcer
  • dyspnoea
  • emotional distress
  • insomnia
1 - 2 years:
  • ataxia
  • fatigue
  • abdominal pain
  • headache
  • hypotension
  • neck pain
  • gastric ulcer
  • general physical health deterioration
  • hepatic function abnormal
  • pneumonia
2 - 5 years:
  • gait disturbance
  • insomnia
  • intentional overdose
  • drug ineffective
  • alcohol poisoning
  • alcoholism
  • amnesia
  • cognitive disorder
  • depression
  • fatigue
5 - 10 years:
  • fatigue
  • pre-existing condition improved
  • therapeutic response unexpected
not specified:
  • pain
  • drug ineffective
  • fall
  • anxiety
  • fatigue
  • nausea
  • depression
  • headache
  • back pain
  • asthenia

Most common drug interactions by gender *:

female:
  • pain
  • fall
  • nausea
  • fatigue
  • drug ineffective
  • diarrhoea
  • anxiety
  • arthralgia
  • back pain
  • headache
male:
  • anxiety
  • drug ineffective
  • depression
  • pain
  • asthenia
  • headache
  • constipation
  • hypoaesthesia
  • back pain
  • insomnia

Most common drug interactions by age *:

10-19:
  • drug ineffective
  • cerebral atrophy
  • confusional state
  • crying
  • discomfort
  • disorientation
  • dystonia
  • fear
  • feeling abnormal
  • hallucination
20-29:
  • drug ineffective
  • nausea
  • pain
  • drug dependence
  • convulsion
  • fall
  • gait disturbance
  • headache
  • pancreatitis
  • rheumatoid arthritis
30-39:
  • pain
  • anxiety
  • asthenia
  • insomnia
  • nausea
  • dyspnoea
  • arthralgia
  • fatigue
  • pain in extremity
  • vomiting
40-49:
  • fatigue
  • anxiety
  • constipation
  • headache
  • depression
  • drug ineffective
  • back pain
  • hypoaesthesia
  • pain
  • insomnia
50-59:
  • fall
  • hypertension
  • pain
  • cough
  • anxiety
  • pyrexia
  • chest pain
  • diarrhoea
  • anaemia
  • nausea
60+:
  • fall
  • nausea
  • pain
  • diarrhoea
  • dehydration
  • drug ineffective
  • asthenia
  • dizziness
  • vomiting
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Amitriptyline hydrochloride and Zanaflex?

Interactions between Amitriptyline hydrochloride and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Zanaflex and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Amitriptyline hydrochloride (amitriptyline hydrochloride) is often used to treat depression. Zanaflex (tizanidine hydrochloride) is often used to treat muscle spasms. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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