Review: taking Amlodipine besylate and Benadryl together


Summary

Drug interactions are reported among people who take Amlodipine besylate and Benadryl together. This review analyzes the effectiveness and drug interactions between Amlodipine besylate and Benadryl. It is created by eHealthMe based on reports of 2,692 people who take the same drugs from FDA and social media, and is updated regularly.

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Amlodipine Besylate

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Amlodipine besylate 24,489 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 43,259 users)

On Sep, 16, 2016

2,692 people who take Amlodipine Besylate, Benadryl are studied.


Number of reports submitted per year:

Amlodipine besylate and Benadryl drug interactions.

Drug effectiveness over time:

Amlodipine Besylate:
  • < 1 month: 33.0% - (2 of 6 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 66.0% - (2 of 3 people)
  • 1 - 6 months: 55.0% - (5 of 9 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 3 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Amlodipine Besylate:
  • female: 53.0% - (8 of 15 people)
  • male: 40.0% - (6 of 15 people)
Benadryl:
  • female: 53.0% - (8 of 15 people)
  • male: 46.0% - (7 of 15 people)

Drug effectiveness by age:

Amlodipine Besylate:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 57.0% - (4 of 7 people)
  • 50-59: 38.0% - (5 of 13 people)
  • 60+: 37.0% - (3 of 8 people)
Benadryl:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 50.0% - (7 of 14 people)
  • 60+: 66.0% - (4 of 6 people)

Most common drug interactions over time *:

< 1 month:
  • hypotension
  • sepsis
  • renal failure
  • dehydration
  • bk virus infection
  • cystitis haemorrhagic
  • cytomegalovirus infection
  • hyperbilirubinaemia
  • mucosal inflammation
  • death
1 - 6 months:
  • hypotension
  • acute respiratory failure
  • haemorrhage intracranial
  • sepsis
  • failure to thrive
  • convulsion
  • pneumonia streptococcal
  • arthralgia
  • cold-stimulus headache
  • depression
6 - 12 months:
  • red blood cell count decreased
  • asthenia
  • fatigue
  • blood bilirubin increased
  • blood pressure increased
  • cough
  • disease progression
  • dyspnoea
  • haematocrit decreased
  • haemoglobin decreased
1 - 2 years:
  • dizziness
  • blood pressure increased
  • vertigo positional
  • dyspepsia
  • dyspnoea
  • pain
  • syncope
  • anxiety
  • atrial fibrillation
  • c-reactive protein increased
2 - 5 years:
  • cough
  • fatigue
  • respiratory rate decreased
  • back pain
  • basal cell carcinoma
  • blood pressure decreased
  • cardiac failure congestive
  • chest pain
  • dehydration
  • dyspnoea
5 - 10 years:
  • diarrhoea
  • neutropenia
  • rash macular
  • septic shock
  • vertigo positional
  • multi-organ failure
  • renal failure
  • arthritis
  • back pain
  • blood pressure increased
10+ years:
  • fatigue
  • weight decreased
  • asthenia
  • decreased appetite
  • dehydration
  • fall
  • muscular weakness
  • diarrhoea
  • mobility decreased
  • activities of daily living impaired
not specified:
  • nausea
  • pain
  • dyspnoea
  • diarrhoea
  • fatigue
  • dizziness
  • vomiting
  • pyrexia
  • asthenia
  • fall

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • dyspnoea
  • diarrhoea
  • dizziness
  • arthralgia
  • pyrexia
  • vomiting
  • headache
  • fall
male:
  • fatigue
  • nausea
  • hypotension
  • asthenia
  • diarrhoea
  • dehydration
  • pain
  • dyspnoea
  • pneumonia
  • dizziness

Most common drug interactions by age *:

0-1:
  • acute respiratory failure
  • clostridial infection
  • culture stool positive
  • cushing's syndrome
  • face oedema
  • graft versus host disease
  • hepatomegaly
  • mental status changes
  • mucosal inflammation
  • pyrexia
2-9:
  • nausea
  • diarrhoea
  • vomiting
  • asthenia
  • dehydration
  • hypertension
  • upper respiratory tract infection
  • anaemia
  • eyelid ptosis
  • lung disorder
10-19:
  • hypotension
  • cardiac arrest
  • convulsion
  • acute respiratory failure
  • haemorrhage intracranial
  • nausea
  • nephrogenic systemic fibrosis
  • pleural effusion
  • sepsis
  • pain in extremity
20-29:
  • infusion related reaction
  • nausea
  • liver disorder
  • blood pressure increased
  • decreased appetite
  • fatigue
  • weight increased
  • gastroenteritis
  • vomiting
  • aggression
30-39:
  • infusion related reaction
  • therapeutic response decreased
  • dyspnoea
  • back pain
  • chest pain
  • headache
  • pain in extremity
  • sepsis
  • nausea
  • vomiting
40-49:
  • hypotension
  • dehydration
  • sepsis
  • nausea
  • pain
  • mucosal inflammation
  • headache
  • pain in extremity
  • bk virus infection
  • cystitis haemorrhagic
50-59:
  • nausea
  • pain
  • pyrexia
  • dizziness
  • chest pain
  • anxiety
  • insomnia
  • arthralgia
  • fall
  • diarrhoea
60+:
  • nausea
  • asthenia
  • diarrhoea
  • fatigue
  • pneumonia
  • fall
  • pain
  • dyspnoea
  • dizziness
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Amlodipine besylate (amlodipine besylate) is often used to treat high blood pressure. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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