Review: taking Amlodipine besylate and Benadryl together


Summary

Drug interactions are reported among people who take Amlodipine besylate and Benadryl together. This review analyzes the effectiveness and drug interactions between Amlodipine besylate and Benadryl. It is created by eHealthMe based on reports of 1,374 people who take the same drugs from FDA and social media, and is updated regularly.

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Amlodipine Besylate

Amlodipine besylate has active ingredients of amlodipine besylate. It is often used in high blood pressure. (latest outcomes from Amlodipine besylate 19,685 users)

Benadryl

Benadryl has active ingredients of diphenhydramine. It is often used in hypersensitivity. (latest outcomes from Benadryl 29,241 users)

On Jul, 20, 2016

1,374 people who take Amlodipine Besylate, Benadryl are studied.


Number of reports submitted per year:

Amlodipine besylate and Benadryl drug interactions.

Drug effectiveness over time:

Amlodipine Besylate:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 18.0% - (2 of 11 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 50.0% - (2 of 4 people)
  • 10+ years: 70.0% - (7 of 10 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 30.0% - (6 of 20 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 42.0% - (3 of 7 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 7 people)
  • 10+ years: 66.0% - (6 of 9 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Amlodipine Besylate:
  • female: 55.0% - (11 of 20 people)
  • male: 26.0% - (6 of 23 people)
Benadryl:
  • female: 40.0% - (11 of 27 people)
  • male: 30.0% - (8 of 26 people)

Drug effectiveness by age:

Amlodipine Besylate:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 36.0% - (4 of 11 people)
  • 50-59: 47.0% - (8 of 17 people)
  • 60+: 23.0% - (3 of 13 people)
Benadryl:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 19.0% - (4 of 21 people)
  • 50-59: 47.0% - (9 of 19 people)
  • 60+: 45.0% - (5 of 11 people)

Most common drug interactions over time *:

< 1 month:
  • hypotension
  • dehydration
  • renal failure
  • bk virus infection
  • cystitis haemorrhagic
  • cytomegalovirus infection
  • hyperbilirubinaemia
  • mucosal inflammation
  • sepsis
  • respiratory failure
1 - 6 months:
  • cold-stimulus headache
  • depression
  • feeling jittery
  • restlessness aggravated
  • arthralgia
  • hypotension
  • diarrhoea
  • anastomotic stenosis
  • arteriovenous fistula occlusion
  • focal segmental glomerulosclerosis
6 - 12 months:
  • red blood cell count decreased
  • blood bilirubin increased
  • haematocrit decreased
  • haemoglobin decreased
  • multi-organ failure
  • platelet count decreased
  • weight increased
  • asthenia
  • cough
  • dizziness
1 - 2 years:
  • blood pressure increased
  • vertigo positional
  • dyspepsia
  • syncope
  • c-reactive protein increased
  • cold-stimulus headache
  • drug ineffective
  • erythema
  • heart rate increased
  • pain
2 - 5 years:
  • fatigue
  • back pain
  • basal cell carcinoma
  • blood pressure decreased
  • chest pain
  • cough
  • dehydration
  • heart rate decreased
  • nausea
  • rash generalised
5 - 10 years:
  • diarrhoea
  • neutropenia
  • rash macular
  • septic shock
  • vertigo positional
  • multi-organ failure
  • renal failure
  • back pain
  • facial pain
  • febrile neutropenia
10+ years:
  • rash
  • depression
  • dizziness aggravated
  • erectile dysfunction
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • night sweats
  • pruritus aggravated
  • restless leg syndrome
  • weight above normal
  • aphonia
not specified:
  • nausea
  • pain
  • pyrexia
  • vomiting
  • chest pain
  • anxiety
  • pain in extremity
  • dizziness
  • arthralgia
  • dyspnoea

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • pain in extremity
  • chest pain
  • pyrexia
  • anxiety
  • dizziness
  • arthralgia
  • vomiting
  • dyspnoea
male:
  • hypotension
  • nausea
  • renal failure
  • dehydration
  • pain
  • asthenia
  • pyrexia
  • pneumonia
  • vomiting
  • sepsis

Most common drug interactions by age *:

0-1:
  • acute respiratory failure
  • clostridial infection
  • culture stool positive
  • cushing's syndrome
  • face oedema
  • graft versus host disease
  • hepatomegaly
  • mental status changes
  • mucosal inflammation
  • pyrexia
2-9:
  • nausea
  • diarrhoea
  • vomiting
  • asthenia
  • dehydration
  • hypertension
  • upper respiratory tract infection
  • pyrexia
  • abdominal distension
  • abdominal pain upper
10-19:
  • cardiac arrest
  • nephrogenic systemic fibrosis
  • pleural effusion
  • blood alkaline phosphatase increased
  • encephalopathy
  • haematochezia
  • hydrocephalus
  • hyperbilirubinaemia
  • hypoxia
  • meningitis bacterial
20-29:
  • alveolar proteinosis
  • anxiety
  • arthralgia
  • aspergilloma
  • blood bilirubin increased
  • blood creatine phosphokinase increased
  • blood creatinine increased
  • blood glucose increased
  • blood lactate dehydrogenase increased
  • blood myoglobin increased
30-39:
  • back pain
  • chest pain
  • blood pressure increased
  • dyspnoea
  • type 2 diabetes mellitus
  • abdominal pain
  • device related infection
  • headache
  • infusion related reaction
  • meningitis aseptic
40-49:
  • hypotension
  • dehydration
  • mucosal inflammation
  • sepsis
  • bk virus infection
  • cystitis haemorrhagic
  • cytomegalovirus infection
  • hyperbilirubinaemia
  • pain in extremity
  • renal failure
50-59:
  • pain
  • nausea
  • chest pain
  • anxiety
  • pyrexia
  • injury
  • insomnia
  • dizziness
  • fall
  • arthralgia
60+:
  • nausea
  • asthenia
  • pyrexia
  • pain
  • pneumonia
  • hypotension
  • back pain
  • fall
  • oedema peripheral
  • pruritus

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Amlodipine besylate (amlodipine besylate) is often used to treat high blood pressure. Benadryl (diphenhydramine) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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