Review: taking Arava and Rituxan together


Summary

Drug interactions are reported among people who take Arava and Rituxan together. This review analyzes the effectiveness and drug interactions between Arava and Rituxan. It is created by eHealthMe based on reports of 420 people who take the same drugs from FDA and social media, and is updated regularly.

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Arava

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. (latest outcomes from Arava 16,099 users)

Rituxan

Rituxan has active ingredients of rituximab. It is often used in non-hodgkin's lymphoma. (latest outcomes from Rituxan 10,201 users)

On Jul, 23, 2016

420 people who take Arava, Rituxan are studied.


Number of reports submitted per year:

Arava and Rituxan drug interactions.

Drug effectiveness over time:

Arava:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 3 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 75.0% - (6 of 8 people)
  • not specified: 0.0% - (0 of 0 people)
Rituxan:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (8 of 8 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Arava:
  • female: 66.0% - (6 of 9 people)
  • male: 33.0% - (1 of 3 people)
Rituxan:
  • female: 66.0% - (6 of 9 people)
  • male: 66.0% - (2 of 3 people)

Drug effectiveness by age:

Arava:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 70.0% - (7 of 10 people)
Rituxan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 80.0% - (8 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • drug ineffective
  • pain
  • arthralgia
  • joint swelling
  • rheumatoid arthritis
  • weight increased
  • headache
  • oedema peripheral
  • pneumonia
  • gait disturbance
1 - 6 months:
  • arthralgia
  • blood pressure increased
  • drug ineffective
  • fall
  • fatigue
  • myocardial infarction
  • dizziness
  • headache
  • hypoaesthesia
  • pain
6 - 12 months:
  • gait disturbance
  • arthropathy
  • back pain
  • bone disorder
  • haemorrhage
  • infarction
  • pain in extremity
  • weight decreased
  • anaemia
  • aneurysm
1 - 2 years:
  • arthralgia
  • dyspnoea
  • oedema
  • oedema peripheral
  • pneumonia
  • bronchopneumonia
  • cardiac failure
  • coronary artery disease
  • cough
  • diverticulum intestinal
2 - 5 years:
  • progressive multifocal leukoencephalopathy
  • bacterial infection
  • duodenal ulcer
  • arthralgia
  • arthropathy
  • intervertebral disc protrusion
  • neck pain
  • neutropenia
  • pneumonia
  • blood glucose increased
5 - 10 years:
  • aneurysm
  • arthropathy
  • bacterial sepsis
  • dilatation ventricular
  • liver abscess
  • myocardial infarction
  • pneumonia
  • renal failure acute
  • abscess
  • anaemia
10+ years:
  • ringing in the ears
  • sweating increased
not specified:
  • pain
  • drug ineffective
  • arthralgia
  • diarrhoea
  • rheumatoid arthritis
  • pneumonia
  • joint swelling
  • dyspnoea
  • weight increased
  • malaise

Most common drug interactions by gender *:

female:
  • drug ineffective
  • pain
  • arthralgia
  • rheumatoid arthritis
  • joint swelling
  • headache
  • pneumonia
  • weight increased
  • gait disturbance
  • pain in extremity
male:
  • pneumonia
  • pyrexia
  • dyspnoea
  • pain
  • cardiac failure
  • weight decreased
  • alanine aminotransferase increased
  • bacterial infection
  • dehydration
  • diarrhoea

Most common drug interactions by age *:

2-9:
  • arthritis bacterial
  • histiocytosis haematophagic
  • hodgkin's disease
  • interstitial lung disease
10-19:
  • hodgkin's disease
  • anaphylactic reaction
  • drug ineffective
  • hodgkin's disease stage ii
  • drug effect decreased
  • joint destruction
  • serum sickness
20-29:
  • squamous cell carcinoma of the cervix
  • acute respiratory distress syndrome
  • pelvic pain
  • vaginal haemorrhage
  • drug exposure during pregnancy
  • feeling of body temperature change
  • gastritis
  • nausea
  • pain
  • thrombosis
30-39:
  • pain
  • arthralgia
  • bone pain
  • dyspnoea
  • fatigue
  • headache
  • nausea
  • pancreatitis necrotising
  • drug ineffective
  • hypersensitivity
40-49:
  • diarrhoea
  • weight increased
  • drug ineffective
  • dyspnoea
  • fatigue
  • pain
  • spinal disorder
  • paraesthesia
  • asthenia
  • neutropenia
50-59:
  • drug ineffective
  • rheumatoid arthritis
  • joint swelling
  • pain
  • arthralgia
  • dizziness
  • eye disorder
  • headache
  • hypersensitivity
  • hypoaesthesia
60+:
  • arthralgia
  • pain
  • sepsis
  • pneumonia
  • fall
  • myocardial infarction
  • spinal disorder
  • weight increased
  • weight decreased
  • bone disorder

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Arava (leflunomide) is often used to treat rheumatoid arthritis. Rituxan (rituximab) is often used to treat non-hodgkin's lymphoma. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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