Review: taking Arava and Rituxan together


Summary

Drug interactions are reported among people who take Arava and Rituxan together. This review analyzes the effectiveness and drug interactions between Arava and Rituxan. It is created by eHealthMe based on reports of 585 people who take the same drugs from FDA and social media, and is updated regularly.

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Arava

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. (latest outcomes from Arava 18,016 users)

Rituxan

Rituxan has active ingredients of rituximab. It is often used in non-hodgkin's lymphoma. (latest outcomes from Rituxan 12,348 users)

On Aug, 22, 2016

585 people who take Arava, Rituxan are studied.


Number of reports submitted per year:

Arava and Rituxan drug interactions.

Drug effectiveness over time:

Arava:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Rituxan:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Arava:
  • female: 33.0% - (1 of 3 people)
  • male: 50.0% - (1 of 2 people)
Rituxan:
  • female: 33.0% - (1 of 3 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Arava:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 50.0% - (2 of 4 people)
Rituxan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 50.0% - (2 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • drug ineffective
  • pain
  • arthralgia
  • joint swelling
  • rheumatoid arthritis
  • weight increased
  • headache
  • oedema peripheral
  • pneumonia
  • gait disturbance
1 - 6 months:
  • arthralgia
  • blood pressure increased
  • drug ineffective
  • fall
  • fatigue
  • myocardial infarction
  • pain
  • depression
  • dizziness
  • headache
6 - 12 months:
  • back pain
  • gait disturbance
  • pain in extremity
  • anaemia
  • arthropathy
  • bone disorder
  • haemorrhage
  • weight decreased
  • blood cholesterol abnormal
  • hypersensitivity
1 - 2 years:
  • pneumonia
  • arthralgia
  • diverticulum intestinal
  • dyspnoea
  • oedema
  • oedema peripheral
  • weight decreased
  • bladder cancer
  • bronchopneumonia
  • cardiac failure
2 - 5 years:
  • progressive multifocal leukoencephalopathy
  • arthralgia
  • arthropathy
  • bacterial infection
  • duodenal ulcer
  • neck pain
  • neutropenia
  • pneumonia
  • cellulitis
  • intervertebral disc protrusion
5 - 10 years:
  • renal failure acute
  • dilatation ventricular
  • liver abscess
  • pneumonia
  • bacterial sepsis
  • gait disturbance
  • myocardial infarction
  • abscess
  • amylase increased
  • anaemia
10+ years:
  • ringing in the ears
  • sweating increased
  • atrial fibrillation
  • diabetes mellitus
  • ear pain
  • erythema
  • eye pain
  • headache
  • pain in jaw
  • poor quality sleep
not specified:
  • infusion related reaction
  • bronchitis
  • pain
  • arthralgia
  • pneumonia
  • drug ineffective
  • rheumatoid arthritis
  • diarrhoea
  • asthenia
  • pyrexia

Most common drug interactions by gender *:

female:
  • drug ineffective
  • arthralgia
  • pain
  • infusion related reaction
  • rheumatoid arthritis
  • joint swelling
  • pneumonia
  • headache
  • weight increased
  • malaise
male:
  • bronchopneumonia
  • pneumonia
  • bronchitis
  • general physical health deterioration
  • diarrhoea
  • asthenia
  • pyrexia
  • headache
  • lung disorder
  • psoriasis

Most common drug interactions by age *:

2-9:
  • arthritis bacterial
  • bladder cancer
  • histiocytosis haematophagic
  • hodgkin's disease
  • interstitial lung disease
  • pruritus
10-19:
  • hodgkin's disease
  • anaphylactic reaction
  • drug ineffective
  • hodgkin's disease stage ii
  • drug effect decreased
  • arthralgia
  • convulsion
  • finger deformity
  • foot deformity
  • hypotension
20-29:
  • squamous cell carcinoma of the cervix
  • acute respiratory distress syndrome
  • pelvic pain
  • vaginal haemorrhage
  • abortion spontaneous
  • drug exposure during pregnancy
  • feeling of body temperature change
  • gastritis
  • nausea
  • pain
30-39:
  • pain
  • fatigue
  • nausea
  • drug ineffective
  • arthralgia
  • bone pain
  • dyspnoea
  • headache
  • hypoaesthesia
  • pancreatitis necrotising
40-49:
  • diarrhoea
  • pain
  • fatigue
  • weight increased
  • drug ineffective
  • arthralgia
  • asthenia
  • bone pain
  • dyspnoea
  • spinal disorder
50-59:
  • drug ineffective
  • rheumatoid arthritis
  • joint swelling
  • arthralgia
  • pain
  • infusion related reaction
  • headache
  • asthenia
  • hypertension
  • oedema peripheral
60+:
  • pneumonia
  • arthralgia
  • pain
  • infusion related reaction
  • sepsis
  • atrial fibrillation
  • psoriasis
  • bronchitis
  • rheumatoid arthritis
  • diabetes mellitus

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Arava (leflunomide) is often used to treat rheumatoid arthritis. Rituxan (rituximab) is often used to treat non-hodgkin's lymphoma. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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