Review: taking Arava and Rituxan together


Summary

Drug interactions are reported among people who take Arava and Rituxan together. This review analyzes the effectiveness and drug interactions between Arava and Rituxan. It is created by eHealthMe based on reports of 1,066 people who take the same drugs from FDA and social media, and is updated regularly.

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Arava

Arava has active ingredients of leflunomide. It is often used in rheumatoid arthritis. (latest outcomes from Arava 22,380 users)

Rituxan

Rituxan has active ingredients of rituximab. It is often used in rheumatoid arthritis. (latest outcomes from Rituxan 18,110 users)

On Sep, 19, 2016

1,066 people who take Arava, Rituxan are studied.


Number of reports submitted per year:

Arava and Rituxan drug interactions.

Drug effectiveness over time:

Arava:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Rituxan:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Arava:
  • female: 33.0% - (1 of 3 people)
  • male: 50.0% - (1 of 2 people)
Rituxan:
  • female: 33.0% - (1 of 3 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Arava:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 50.0% - (2 of 4 people)
Rituxan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 50.0% - (2 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • drug ineffective
  • pain
  • arthralgia
  • rheumatoid arthritis
  • joint swelling
  • oedema peripheral
  • pneumonia
  • headache
  • weight increased
  • weight decreased
1 - 6 months:
  • drug ineffective
  • rheumatoid arthritis
  • nausea
  • arthralgia
  • drug intolerance
  • blood pressure increased
  • fall
  • fatigue
  • liver function test abnormal
  • myocardial infarction
6 - 12 months:
  • drug ineffective
  • pain in extremity
  • weight decreased
  • back pain
  • gait disturbance
  • infusion related reaction
  • anaemia
  • arthropathy
  • bone disorder
  • death
1 - 2 years:
  • weight decreased
  • arthralgia
  • pneumonia
  • pyrexia
  • chills
  • dyspnoea
  • arthropathy
  • cardiac failure
  • diverticulum intestinal
  • drug ineffective
2 - 5 years:
  • progressive multifocal leukoencephalopathy
  • hyponatraemia
  • lower respiratory tract infection
  • arthralgia
  • arthropathy
  • drug ineffective
  • pneumonia
  • bacterial infection
  • duodenal ulcer
  • neck pain
5 - 10 years:
  • pneumonia
  • renal failure acute
  • drug ineffective
  • arthralgia
  • dilatation ventricular
  • liver abscess
  • bacterial sepsis
  • gait disturbance
  • myocardial infarction
  • pain in extremity
10+ years:
  • ringing in the ears
  • drug ineffective
  • red blood cell sedimentation rate increased
  • c-reactive protein increased
  • drug hypersensitivity
  • hypertension
  • pulmonary fibrosis
  • sweating increased
  • synovitis
  • treatment failure
not specified:
  • drug ineffective
  • infusion related reaction
  • rheumatoid arthritis
  • arthralgia
  • diarrhoea
  • pain
  • joint swelling
  • bronchitis
  • fatigue
  • dyspnoea

Most common drug interactions by gender *:

female:
  • drug ineffective
  • rheumatoid arthritis
  • infusion related reaction
  • arthralgia
  • pain
  • joint swelling
  • diarrhoea
  • fatigue
  • weight decreased
  • malaise
male:
  • bronchopneumonia
  • diarrhoea
  • pneumonia
  • bronchitis
  • rheumatoid arthritis
  • drug ineffective
  • infusion related reaction
  • arthralgia
  • asthenia
  • dyspnoea

Most common drug interactions by age *:

2-9:
  • cardiac failure
  • infection
  • pneumonia
  • serum sickness
  • arthritis bacterial
  • bladder cancer
  • device related infection
  • drug resistance
  • epistaxis
  • histiocytosis haematophagic
10-19:
  • hodgkin's disease
  • anaphylactic reaction
  • drug ineffective
  • hodgkin's disease stage ii
  • drug effect decreased
  • arthralgia
  • convulsion
  • finger deformity
  • foot deformity
  • hypotension
20-29:
  • drug ineffective
  • fatigue
  • arthralgia
  • diarrhoea
  • discomfort
  • gastroenteritis
  • hypertension
  • infection
  • inflammation
  • weight increased
30-39:
  • drug ineffective
  • fatigue
  • nausea
  • pain
  • arthralgia
  • insomnia
  • neck pain
  • bone pain
  • dyspnoea
  • headache
40-49:
  • drug ineffective
  • pain
  • diarrhoea
  • fatigue
  • rheumatoid arthritis
  • weight increased
  • cough
  • blood pressure increased
  • arthralgia
  • infusion related reaction
50-59:
  • drug ineffective
  • rheumatoid arthritis
  • infusion related reaction
  • arthralgia
  • joint swelling
  • weight decreased
  • pain
  • dizziness
  • headache
  • nausea
60+:
  • infusion related reaction
  • rheumatoid arthritis
  • arthralgia
  • diarrhoea
  • drug ineffective
  • pneumonia
  • pain
  • joint swelling
  • blood pressure increased
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Arava (leflunomide) is often used to treat rheumatoid arthritis. Rituxan (rituximab) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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