Review: taking Aricept and Namenda together


Summary

Drug interactions are reported among people who take Aricept and Namenda together. This review analyzes the effectiveness and drug interactions between Aricept and Namenda. It is created by eHealthMe based on reports of 3,484 people who take the same drugs from FDA and social media, and is updated regularly.

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Aricept

Aricept has active ingredients of donepezil hydrochloride. It is often used in dementia alzheimer's type. (latest outcomes from Aricept 15,657 users)

Namenda

Namenda has active ingredients of memantine hydrochloride. It is often used in dementia alzheimer's type. (latest outcomes from Namenda 7,388 users)

On Aug, 17, 2016

3,484 people who take Aricept, Namenda are studied.


Number of reports submitted per year:

Aricept and Namenda drug interactions.

Drug effectiveness over time:

Aricept:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 3.0% - (1 of 26 people)
  • 6 - 12 months: 10.0% - (2 of 19 people)
  • 1 - 2 years: 6.0% - (1 of 16 people)
  • 2 - 5 years: 17.0% - (7 of 40 people)
  • 5 - 10 years: 7.0% - (1 of 14 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 1 people)
Namenda:
  • < 1 month: 0.0% - (0 of 5 people)
  • 1 - 6 months: 4.0% - (1 of 21 people)
  • 6 - 12 months: 10.0% - (2 of 20 people)
  • 1 - 2 years: 12.0% - (3 of 24 people)
  • 2 - 5 years: 24.0% - (8 of 33 people)
  • 5 - 10 years: 10.0% - (1 of 10 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Aricept:
  • female: 13.0% - (10 of 72 people)
  • male: 6.0% - (3 of 50 people)
Namenda:
  • female: 14.0% - (10 of 67 people)
  • male: 10.0% - (5 of 49 people)

Drug effectiveness by age:

Aricept:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 10.0% - (12 of 117 people)
Namenda:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 11.0% - (13 of 112 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • dizziness
  • confusional state
  • fall
  • gait disturbance
  • insomnia
  • asthenia
  • nausea
  • agitation
  • convulsion
1 - 6 months:
  • somnolence
  • agitation
  • fall
  • abnormal behaviour
  • dizziness
  • loss of consciousness
  • decreased appetite
  • dehydration
  • confusional state
  • disturbance in attention
6 - 12 months:
  • dizziness
  • fall
  • gait disturbance
  • nausea
  • oedema peripheral
  • erythema
  • malaise
  • somnolence
  • abdominal discomfort
  • bradycardia
1 - 2 years:
  • sopor
  • confusional state
  • fall
  • urinary tract infection
  • cholelithiasis
  • convulsion
  • decubitus ulcer
  • gait disturbance
  • agitation
  • syncope
2 - 5 years:
  • dizziness
  • confusional state
  • diarrhoea
  • syncope
  • confusion
  • disorientation
  • fall
  • fatigue
  • general physical health deterioration
  • aggression
5 - 10 years:
  • anxiety
  • blood alkaline phosphatase increased
  • chronic pain
  • constipation
  • dehydration
  • depression
  • frontotemporal dementia
  • primary progressive aphasia
  • short-term memory loss
  • tremor
10+ years:
  • blood alkaline phosphatase increased
  • dementia alzheimer's type
  • agitation aggravated
  • anaemia
  • aortic stenosis
  • emotional poverty
  • fall
  • hallucination, auditory
  • renal impairment
  • somnolence
not specified:
  • confusional state
  • fall
  • somnolence
  • dizziness
  • asthenia
  • urinary tract infection
  • fatigue
  • nausea
  • agitation
  • diarrhoea

Most common drug interactions by gender *:

female:
  • confusional state
  • somnolence
  • fall
  • dizziness
  • urinary tract infection
  • tremor
  • agitation
  • asthenia
  • fatigue
  • convulsion
male:
  • confusional state
  • dizziness
  • somnolence
  • fall
  • asthenia
  • nausea
  • gait disturbance
  • diarrhoea
  • agitation
  • fatigue

Most common drug interactions by age *:

0-1:
  • cardiac failure congestive
  • death
  • diabetes mellitus
2-9:
  • encephalopathy
  • agitation
  • hallucination, visual
  • body temperature increased
  • drug level increased
  • heart rate increased
  • blood pressure abnormal
  • blood pressure diastolic decreased
  • constipation
  • ecchymosis
10-19:
  • abdominal pain
  • arthritis
  • back disorder
  • blindness
  • bone density decreased
  • calcium deficiency
  • cataract
  • cerebrovascular accident
  • cyst
  • depression
20-29:
  • ventricular fibrillation
  • agitation
  • disease recurrence
  • extrasystoles
  • hospitalisation
  • sexual dysfunction
30-39:
  • depression
  • suicide attempt
  • cognitive disorder
  • apraxia
  • convulsion
  • drug effect decreased
  • hypotension
  • muscle spasms
  • weight increased
  • aggression
40-49:
  • death
  • fatigue
  • tachycardia
  • confusional state
  • headache
  • tremor
  • atrial fibrillation
  • brain oedema
  • convulsion
  • gait disturbance
50-59:
  • fall
  • dizziness
  • agitation
  • asthenia
  • chest pain
  • confusional state
  • headache
  • gait disturbance
  • abnormal behaviour
  • aggression
60+:
  • confusional state
  • somnolence
  • dizziness
  • fall
  • asthenia
  • urinary tract infection
  • agitation
  • fatigue
  • nausea
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Aricept (donepezil hydrochloride) is often used to treat dementia alzheimer's type. Namenda (memantine hydrochloride) is often used to treat dementia alzheimer's type. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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