Review: taking Aricept and Namenda together


Summary

Drug interactions are reported among people who take Aricept and Namenda together. This review analyzes the effectiveness and drug interactions between Aricept and Namenda. It is created by eHealthMe based on reports of 4,159 people who take the same drugs from FDA and social media, and is updated regularly.

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Aricept

Aricept has active ingredients of donepezil hydrochloride. It is often used in dementia alzheimer's type. (latest outcomes from Aricept 18,539 users)

Namenda

Namenda has active ingredients of memantine hydrochloride. It is often used in dementia alzheimer's type. (latest outcomes from Namenda 9,312 users)

On Sep, 20, 2016

4,159 people who take Aricept, Namenda are studied.


Number of reports submitted per year:

Aricept and Namenda drug interactions.

Drug effectiveness over time:

Aricept:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 4.0% - (1 of 25 people)
  • 6 - 12 months: 10.0% - (2 of 19 people)
  • 1 - 2 years: 6.0% - (1 of 16 people)
  • 2 - 5 years: 17.0% - (7 of 40 people)
  • 5 - 10 years: 7.0% - (1 of 14 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 1 people)
Namenda:
  • < 1 month: 0.0% - (0 of 5 people)
  • 1 - 6 months: 5.0% - (1 of 20 people)
  • 6 - 12 months: 10.0% - (2 of 20 people)
  • 1 - 2 years: 12.0% - (3 of 24 people)
  • 2 - 5 years: 24.0% - (8 of 33 people)
  • 5 - 10 years: 10.0% - (1 of 10 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Aricept:
  • female: 14.0% - (10 of 71 people)
  • male: 6.0% - (3 of 50 people)
Namenda:
  • female: 15.0% - (10 of 66 people)
  • male: 10.0% - (5 of 49 people)

Drug effectiveness by age:

Aricept:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 0.0% - (0 of 4 people)
  • 60+: 10.0% - (12 of 116 people)
Namenda:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 11.0% - (13 of 111 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • confusional state
  • dizziness
  • fall
  • gait disturbance
  • asthenia
  • insomnia
  • nausea
  • agitation
  • decreased appetite
1 - 6 months:
  • somnolence
  • fall
  • agitation
  • dizziness
  • abnormal behaviour
  • loss of consciousness
  • decreased appetite
  • dehydration
  • confusional state
  • feeling abnormal
6 - 12 months:
  • dizziness
  • fall
  • gait disturbance
  • nausea
  • oedema peripheral
  • erythema
  • malaise
  • somnolence
  • abdominal discomfort
  • bradycardia
1 - 2 years:
  • sopor
  • confusional state
  • fall
  • urinary tract infection
  • syncope
  • cholelithiasis
  • convulsion
  • decubitus ulcer
  • gait disturbance
  • agitation
2 - 5 years:
  • dizziness
  • confusional state
  • diarrhoea
  • fall
  • syncope
  • confusion
  • disorientation
  • fatigue
  • general physical health deterioration
  • aggression
5 - 10 years:
  • dementia alzheimer's type
  • constipation
  • dehydration
  • fall
  • abdominal distension
  • abdominal pain
  • agitation
  • anxiety
  • arrhythmia
  • blood alkaline phosphatase increased
10+ years:
  • blood alkaline phosphatase increased
  • dementia alzheimer's type
  • agitation aggravated
  • anaemia
  • aortic stenosis
  • emotional poverty
  • fall
  • hallucination, auditory
  • renal impairment
  • somnolence
not specified:
  • confusional state
  • fall
  • somnolence
  • dizziness
  • asthenia
  • urinary tract infection
  • fatigue
  • diarrhoea
  • nausea
  • agitation

Most common drug interactions by gender *:

female:
  • confusional state
  • fall
  • somnolence
  • dizziness
  • urinary tract infection
  • tremor
  • agitation
  • asthenia
  • fatigue
  • convulsion
male:
  • confusional state
  • fall
  • dizziness
  • asthenia
  • somnolence
  • nausea
  • diarrhoea
  • gait disturbance
  • fatigue
  • agitation

Most common drug interactions by age *:

0-1:
  • cardiac failure congestive
  • death
  • diabetes mellitus
2-9:
  • encephalopathy
  • hallucination, visual
  • agitation
  • accidental overdose
  • eye movement disorder
  • dystonia
  • heart rate increased
  • lethargy
  • respiratory rate increased
  • toxic encephalopathy
10-19:
  • abdominal pain
  • arthritis
  • back disorder
  • blindness
  • bone density decreased
  • calcium deficiency
  • cataract
  • cerebrovascular accident
  • cyst
  • depression
20-29:
  • ventricular fibrillation
  • agitation
  • deep vein thrombosis
  • disease recurrence
  • extrasystoles
  • hospitalisation
  • pulmonary embolism
  • sexual dysfunction
  • thrombocytopenia
30-39:
  • depression
  • suicide attempt
  • cognitive disorder
  • apraxia
  • convulsion
  • drug effect decreased
  • hypotension
  • muscle spasms
  • weight increased
  • aggression
40-49:
  • death
  • fatigue
  • tachycardia
  • confusional state
  • gait disturbance
  • headache
  • tremor
  • atrial fibrillation
  • brain oedema
  • convulsion
50-59:
  • fall
  • dizziness
  • weight decreased
  • agitation
  • asthenia
  • confusional state
  • headache
  • chest pain
  • depression
  • nasopharyngitis
60+:
  • confusional state
  • fall
  • somnolence
  • dizziness
  • asthenia
  • urinary tract infection
  • diarrhoea
  • fatigue
  • nausea
  • agitation

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Aricept (donepezil hydrochloride) is often used to treat dementia alzheimer's type. Namenda (memantine hydrochloride) is often used to treat dementia alzheimer's type. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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