Review: taking Aricept and Namenda together


Summary

Drug interactions are reported among people who take Aricept and Namenda together. This review analyzes the effectiveness and drug interactions between Aricept and Namenda. It is created by eHealthMe based on reports of 3,080 people who take the same drugs from FDA and social media, and is updated regularly.

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Aricept

Aricept has active ingredients of donepezil hydrochloride. It is often used in dementia alzheimer's type. (latest outcomes from Aricept 15,267 users)

Namenda

Namenda has active ingredients of memantine hydrochloride. It is often used in dementia alzheimer's type. (latest outcomes from Namenda 7,145 users)

On Jul, 22, 2016

3,080 people who take Aricept, Namenda are studied.


Number of reports submitted per year:

Aricept and Namenda drug interactions.

Drug effectiveness over time:

Aricept:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 3.0% - (1 of 30 people)
  • 6 - 12 months: 5.0% - (2 of 36 people)
  • 1 - 2 years: 5.0% - (1 of 18 people)
  • 2 - 5 years: 21.0% - (10 of 46 people)
  • 5 - 10 years: 6.0% - (1 of 15 people)
  • 10+ years: 20.0% - (1 of 5 people)
  • not specified: 0.0% - (0 of 1 people)
Namenda:
  • < 1 month: 0.0% - (0 of 7 people)
  • 1 - 6 months: 4.0% - (1 of 24 people)
  • 6 - 12 months: 9.0% - (2 of 21 people)
  • 1 - 2 years: 14.0% - (4 of 27 people)
  • 2 - 5 years: 21.0% - (11 of 52 people)
  • 5 - 10 years: 9.0% - (1 of 11 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Aricept:
  • female: 13.0% - (13 of 99 people)
  • male: 5.0% - (3 of 55 people)
Namenda:
  • female: 14.0% - (13 of 91 people)
  • male: 11.0% - (6 of 54 people)

Drug effectiveness by age:

Aricept:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 0.0% - (0 of 5 people)
  • 60+: 9.0% - (14 of 147 people)
Namenda:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (2 of 2 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 10.0% - (15 of 139 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • dizziness
  • somnolence
  • fall
  • asthenia
  • insomnia
  • nausea
  • agitation
  • gait disturbance
  • diarrhoea
1 - 6 months:
  • somnolence
  • agitation
  • fall
  • abnormal behaviour
  • decreased appetite
  • dizziness
  • fatigue
  • loss of consciousness
  • dehydration
  • feeling abnormal
6 - 12 months:
  • dizziness
  • fall
  • nausea
  • oedema peripheral
  • erythema
  • gait disturbance
  • malaise
  • somnolence
  • abdominal discomfort
  • bradycardia
1 - 2 years:
  • sopor
  • confusional state
  • convulsion
  • gait disturbance
  • urinary tract infection
  • cholelithiasis
  • decubitus ulcer
  • fall
  • agitation
  • syncope
2 - 5 years:
  • dizziness
  • confusional state
  • syncope
  • confusion
  • disorientation
  • fatigue
  • convulsion
  • diarrhoea
  • gallbladder cancer metastatic
  • general physical health deterioration
5 - 10 years:
  • anxiety
  • blood alkaline phosphatase increased
  • chronic pain
  • constipation
  • depression
  • frontotemporal dementia
  • primary progressive aphasia
  • short-term memory loss
  • tremor
  • urinary incontinence
10+ years:
  • blood alkaline phosphatase increased
  • agitation aggravated
  • anaemia
  • aortic stenosis
  • emotional poverty
  • fall
  • hallucination, auditory
  • somnolence
  • teeth grinding and clenching
  • weakness
not specified:
  • confusional state
  • fall
  • somnolence
  • dizziness
  • asthenia
  • urinary tract infection
  • fatigue
  • agitation
  • nausea
  • tremor

Most common drug interactions by gender *:

female:
  • confusional state
  • fall
  • somnolence
  • dizziness
  • urinary tract infection
  • tremor
  • asthenia
  • agitation
  • fatigue
  • convulsion
male:
  • confusional state
  • dizziness
  • somnolence
  • asthenia
  • nausea
  • fall
  • diarrhoea
  • gait disturbance
  • fatigue
  • agitation

Most common drug interactions by age *:

0-1:
  • cardiac failure congestive
  • death
  • diabetes mellitus
2-9:
  • blood pressure abnormal
  • constipation
  • ecchymosis
  • lip swelling
10-19:
  • neutrophil count decreased
  • pharyngitis streptococcal
20-29:
  • ventricular fibrillation
  • agitation
  • hospitalisation
  • sexual dysfunction
30-39:
  • depression
  • suicide attempt
  • cognitive disorder
  • apraxia
  • convulsion
  • drug effect decreased
  • hypotension
  • muscle spasms
  • weight increased
  • asthenia
40-49:
  • death
  • fatigue
  • tachycardia
  • confusional state
  • headache
  • tremor
  • atrial fibrillation
  • brain oedema
  • convulsion
  • gait disturbance
50-59:
  • dizziness
  • fall
  • asthenia
  • chest pain
  • headache
  • agitation
  • gait disturbance
  • arthritis
  • cardiac failure congestive
  • confusional state
60+:
  • confusional state
  • somnolence
  • dizziness
  • fall
  • asthenia
  • urinary tract infection
  • fatigue
  • agitation
  • nausea
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Aricept (donepezil hydrochloride) is often used to treat dementia alzheimer's type. Namenda (memantine hydrochloride) is often used to treat dementia alzheimer's type. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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