Review: taking Astepro and Benadryl together


Summary

Drug interactions are reported among people who take Astepro and Benadryl together. This review analyzes the effectiveness and drug interactions between Astepro and Benadryl. It is created by eHealthMe based on reports of 444 people who take the same drugs from FDA and social media, and is updated regularly.

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Astepro

Astepro has active ingredients of azelastine hydrochloride. It is often used in allergic rhinitis. (latest outcomes from Astepro 1,508 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 43,259 users)

On Sep, 18, 2016

444 people who take Astepro, Benadryl are studied.


Number of reports submitted per year:

Astepro and Benadryl drug interactions.

Drug effectiveness over time:

Astepro:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 66.0% - (2 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 100.0% - (2 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 0.0% - (0 of 4 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Astepro:
  • female: 62.0% - (5 of 8 people)
  • male: 0.0% - (0 of 1 people)
Benadryl:
  • female: 37.0% - (3 of 8 people)
  • male: 0.0% - (0 of 2 people)

Drug effectiveness by age:

Astepro:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 66.0% - (4 of 6 people)
  • 60+: 0.0% - (0 of 1 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 50.0% - (3 of 6 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • bacteraemia
  • fluid overload
  • ileus
  • arrhythmias
  • headache
  • hypotension
  • influenza like illness
  • musculoskeletal pain
  • myalgia
  • nasal congestion
1 - 6 months:
  • dehydration
  • dermatitis acneiform
  • fall
  • stomatitis
  • tachycardia
  • enteritis infectious
  • femoral hernia, obstructive
  • blood creatine phosphokinase increased
  • chest pain
  • hypernatraemia
6 - 12 months:
  • diarrhoea
  • abdominal pain upper
  • diarrhoea haemorrhagic
  • nausea
  • vomiting
  • hyponatraemia
  • urinary tract infection
  • anaemia
  • asthenia
  • blood creatinine increased
2 - 5 years:
  • anger
  • dizziness (excl vertigo)
  • edema
  • nausea in the morning - females
5 - 10 years:
  • arrhythmias
  • supraventricular tachycardia
10+ years:
  • anger
  • dizziness (excl vertigo)
  • edema
  • nausea in the morning - females
not specified:
  • nausea
  • sinusitis
  • pain
  • headache
  • fatigue
  • chest pain
  • cough
  • anxiety
  • fall
  • diarrhoea

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • sinusitis
  • headache
  • fatigue
  • fall
  • diarrhoea
  • chest pain
  • anxiety
  • cough
male:
  • chest pain
  • nausea
  • pyrexia
  • headache
  • fatigue
  • sinusitis
  • cough
  • anxiety
  • pneumonia
  • diarrhoea

Most common drug interactions by age *:

10-19:
  • nausea
  • fatigue
  • abdominal pain upper
  • arthralgia
  • suicidal ideation
  • weight decreased
  • chest pain
  • drug ineffective
  • drug withdrawal syndrome
  • insomnia
20-29:
  • urticaria
  • flushing
  • nasal congestion
  • pruritus
  • diarrhoea
  • injury
  • neuroleptic malignant syndrome
  • pain
  • abdominal pain
  • abdominal pain lower
30-39:
  • status asthmaticus
  • anaphylactic reaction
  • dyspnoea
  • pain
  • arthralgia
  • chest pain
  • chills
  • dizziness
  • insomnia
  • anxiety
40-49:
  • oedema peripheral
  • asthma
  • back pain
  • cholestasis
  • headache
  • weight increased
  • amnesia
  • arthralgia
  • dizziness
  • fall
50-59:
  • nausea
  • diarrhoea
  • headache
  • sinusitis
  • chest pain
  • cough
  • pain
  • anxiety
  • abscess
  • atelectasis
60+:
  • nausea
  • headache
  • fatigue
  • asthenia
  • hypertension
  • sinusitis
  • dizziness
  • vomiting
  • fall
  • muscle spasms

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Astepro (azelastine hydrochloride) is often used to treat allergic rhinitis. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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