Review: taking Baclofen and Benadryl together


Summary

Drug interactions are reported among people who take Baclofen and Benadryl together. This review analyzes the effectiveness and drug interactions between Baclofen and Benadryl. It is created by eHealthMe based on reports of 883 people who take the same drugs from FDA and social media, and is updated regularly.

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Baclofen

Baclofen has active ingredients of baclofen. It is often used in muscle spasticity. (latest outcomes from Baclofen 41,251 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 43,259 users)

On Sep, 16, 2016

883 people who take Baclofen, Benadryl are studied.


Number of reports submitted per year:

Baclofen and Benadryl drug interactions.

Drug effectiveness over time:

Baclofen:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 33.0% - (2 of 6 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Baclofen:
  • female: 29.0% - (5 of 17 people)
  • male: 50.0% - (2 of 4 people)
Benadryl:
  • female: 47.0% - (8 of 17 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Baclofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 25.0% - (2 of 8 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 50.0% - (1 of 2 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 62.0% - (5 of 8 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • headache
  • pain
  • vomiting
  • hypothyroidism
  • urinary tract infection
  • drug ineffective
  • dyspnoea
  • pneumonia
  • suicidal ideation
  • cystitis
1 - 6 months:
  • fatigue
  • constipation
  • drug withdrawal syndrome
  • blood pressure increased
  • diastolic blood pressure
  • drowsiness
  • ear infection
  • interruption of aortic arch
  • irritability
  • micturition frequency decreased
6 - 12 months:
  • constipation
  • pain
  • abdominal pain
  • abnormal dreams
  • adrenal insufficiency
  • anxiety
  • confusional state
  • dizziness postural
  • dry mouth
  • dysuria
1 - 2 years:
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • constipation
  • drug dependence
  • hepatic necrosis
  • pneumonia
  • drug withdrawal syndrome
  • withdrawal syndrome
  • altered state of consciousness
  • anxiety aggravated
2 - 5 years:
  • diastolic blood pressure
  • drowsiness
  • fatigue
  • interruption of aortic arch
  • micturition frequency decreased
  • myelodysplastic syndrome
  • passed out
  • pressure sore
  • blood pressure increased
  • constipation
5 - 10 years:
  • burning eyes
10+ years:
  • ear pain
  • eye floaters
  • eyes - sensitive to light
  • headache - tension
  • menstruation - painful
  • pain
  • acne
not specified:
  • pain
  • urinary tract infection
  • nausea
  • fall
  • vomiting
  • fatigue
  • anxiety
  • diarrhoea
  • arthralgia
  • dyspnoea

Most common drug interactions by gender *:

female:
  • urinary tract infection
  • pain
  • fall
  • nausea
  • vomiting
  • headache
  • anxiety
  • diarrhoea
  • hypoaesthesia
  • arthralgia
male:
  • pain
  • fatigue
  • nausea
  • anxiety
  • diarrhoea
  • headache
  • vomiting
  • dyspnoea
  • arthralgia
  • pneumonia

Most common drug interactions by age *:

0-1:
  • anaemia
  • blood urea decreased
  • bone marrow failure
  • carbon dioxide increased
  • clostridium difficile colitis
  • dermatitis
  • dermatitis diaper
  • device related infection
  • diarrhoea
  • dysphagia
2-9:
  • aphthous stomatitis
  • gastric ulcer
  • haematochezia
  • haematocrit decreased
  • lymphadenopathy
  • lymphoproliferative disorder
  • diarrhoea
  • pyrexia
  • viral infection
  • vomiting
10-19:
  • convulsion
  • drug withdrawal syndrome
  • malaise
  • muscle spasticity
  • clonus
  • hypertonia
  • implant site infection
  • irritability
  • pneumonia streptococcal
  • pulmonary congestion
20-29:
  • pain
  • dyspnoea
  • pyrexia
  • vomiting
  • ear pain
  • fatigue
  • pneumonia
  • constipation
  • anxiety
  • arthritis
30-39:
  • pain
  • pneumonia
  • headache
  • nausea
  • completed suicide
  • constipation
  • dyspnoea
  • fatigue
  • hyperthyroidism
  • hypothyroidism
40-49:
  • headache
  • pneumonia
  • fatigue
  • pain
  • urinary tract infection
  • nausea
  • bronchitis
  • cystitis
  • diarrhoea
  • vomiting
50-59:
  • urinary tract infection
  • pain
  • arthralgia
  • fall
  • anxiety
  • nausea
  • decreased appetite
  • infection
  • osteoarthritis
  • emotional distress
60+:
  • pain
  • nausea
  • vomiting
  • fall
  • urinary tract infection
  • constipation
  • fatigue
  • confusional state
  • anxiety
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasticity. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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