Review: taking Baclofen and Benadryl together


Summary

Drug interactions are reported among people who take Baclofen and Benadryl together. This review analyzes the effectiveness and drug interactions between Baclofen and Benadryl. It is created by eHealthMe based on reports of 548 people who take the same drugs from FDA and social media, and is updated regularly.

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Baclofen

Baclofen has active ingredients of baclofen. It is often used in muscle spasticity. (latest outcomes from Baclofen 26,118 users)

Benadryl

Benadryl has active ingredients of diphenhydramine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Benadryl 32,636 users)

On Aug, 19, 2016

548 people who take Baclofen, Benadryl are studied.


Number of reports submitted per year:

Baclofen and Benadryl drug interactions.

Drug effectiveness over time:

Baclofen:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 33.0% - (2 of 6 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Benadryl:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Baclofen:
  • female: 29.0% - (5 of 17 people)
  • male: 50.0% - (2 of 4 people)
Benadryl:
  • female: 47.0% - (8 of 17 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Baclofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 25.0% - (2 of 8 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 50.0% - (1 of 2 people)
Benadryl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 50.0% - (4 of 8 people)
  • 40-49: 62.0% - (5 of 8 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • headache
  • suicidal ideation
  • nausea
  • pain
  • vomiting
  • abdominal pain
  • anxiety
  • confusional state
  • hyperthyroidism
  • hypothyroidism
1 - 6 months:
  • constipation
  • fatigue
  • blood pressure increased
  • diastolic blood pressure
  • drowsiness
  • interruption of aortic arch
  • micturition frequency decreased
  • pain
  • passed out
  • pressure sore
6 - 12 months:
  • constipation
  • abdominal pain
  • abnormal dreams
  • adrenal insufficiency
  • anxiety
  • confusional state
  • dizziness postural
  • dry mouth
  • dysuria
  • excoriation
1 - 2 years:
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • constipation
  • drug dependence
  • hepatic necrosis
  • pneumonia
  • drug withdrawal syndrome
  • withdrawal syndrome
  • anxiety aggravated
  • breath odour
2 - 5 years:
  • diastolic blood pressure
  • drowsiness
  • fatigue
  • interruption of aortic arch
  • micturition frequency decreased
  • myelodysplastic syndrome
  • passed out
  • pressure sore
  • blood pressure increased
  • constipation
5 - 10 years:
  • burning eyes
10+ years:
  • ear pain
  • eye floaters
  • eyes - sensitive to light
  • headache - tension
  • menstruation - painful
  • pain
  • acne
not specified:
  • pain
  • nausea
  • fall
  • urinary tract infection
  • dyspnoea
  • anxiety
  • vomiting
  • arthralgia
  • pain in extremity
  • diarrhoea

Most common drug interactions by gender *:

female:
  • pain
  • fall
  • urinary tract infection
  • nausea
  • vomiting
  • anxiety
  • dyspnoea
  • pain in extremity
  • diarrhoea
  • headache
male:
  • pain
  • fatigue
  • nausea
  • dyspnoea
  • anxiety
  • arthralgia
  • osteoarthritis
  • osteonecrosis of jaw
  • injury
  • intervertebral disc protrusion

Most common drug interactions by age *:

2-9:
  • aphthous stomatitis
  • gastric ulcer
  • haematochezia
  • haematocrit decreased
  • lymphadenopathy
  • lymphoproliferative disorder
  • pneumonia
  • rectal haemorrhage
  • anorexia
  • blood pressure increased
10-19:
  • convulsion
  • drug withdrawal syndrome
  • muscle spasticity
  • clonus
  • hypertonia
  • implant site infection
  • irritability
  • malaise
  • pneumonia streptococcal
  • pulmonary congestion
20-29:
  • pain
  • dyspnoea
  • ear pain
  • vomiting
  • bronchitis
  • diarrhoea
  • nausea
  • pyrexia
  • arthralgia
  • arthritis
30-39:
  • pneumonia
  • nausea
  • pain
  • constipation
  • dyspnoea
  • headache
  • hyperthyroidism
  • hypothyroidism
  • acute respiratory distress syndrome
  • chest discomfort
40-49:
  • headache
  • suicidal ideation
  • fatigue
  • nausea
  • pain
  • pain in extremity
  • oedema peripheral
  • fall
  • anxiety
  • dyspnoea
50-59:
  • fall
  • arthralgia
  • pain
  • urinary tract infection
  • anxiety
  • emotional distress
  • osteoarthritis
  • osteonecrosis of jaw
  • spinal column stenosis
  • decreased appetite
60+:
  • pain
  • nausea
  • urinary tract infection
  • fall
  • vomiting
  • constipation
  • fatigue
  • confusional state
  • abdominal pain
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasticity. Benadryl (diphenhydramine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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