Review: taking Baclofen and Gabapentin together


Summary

Drug interactions are reported among people who take Baclofen and Gabapentin together. This review analyzes the effectiveness and drug interactions between Baclofen and Gabapentin. It is created by eHealthMe based on reports of 4,404 people who take the same drugs from FDA and social media, and is updated regularly.

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Baclofen

Baclofen has active ingredients of baclofen. It is often used in muscle spasticity. (latest outcomes from Baclofen 20,853 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 38,775 users)

On Jul, 20, 2016

4,404 people who take Baclofen, Gabapentin are studied.


Number of reports submitted per year:

Baclofen and Gabapentin drug interactions.

Drug effectiveness over time:

Baclofen:
  • < 1 month: 12.0% - (2 of 16 people)
  • 1 - 6 months: 34.0% - (14 of 41 people)
  • 6 - 12 months: 6.0% - (1 of 16 people)
  • 1 - 2 years: 32.0% - (13 of 40 people)
  • 2 - 5 years: 30.0% - (15 of 49 people)
  • 5 - 10 years: 24.0% - (8 of 33 people)
  • 10+ years: 50.0% - (10 of 20 people)
  • not specified: 0.0% - (0 of 3 people)
Gabapentin:
  • < 1 month: 23.0% - (3 of 13 people)
  • 1 - 6 months: 8.0% - (3 of 35 people)
  • 6 - 12 months: 5.0% - (1 of 17 people)
  • 1 - 2 years: 14.0% - (6 of 41 people)
  • 2 - 5 years: 36.0% - (15 of 41 people)
  • 5 - 10 years: 20.0% - (9 of 43 people)
  • 10+ years: 45.0% - (11 of 24 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Baclofen:
  • female: 29.0% - (47 of 157 people)
  • male: 26.0% - (16 of 61 people)
Gabapentin:
  • female: 21.0% - (34 of 155 people)
  • male: 23.0% - (15 of 63 people)

Drug effectiveness by age:

Baclofen:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 33.0% - (2 of 6 people)
  • 30-39: 35.0% - (13 of 37 people)
  • 40-49: 27.0% - (20 of 74 people)
  • 50-59: 32.0% - (23 of 71 people)
  • 60+: 17.0% - (5 of 28 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 6 people)
  • 30-39: 23.0% - (9 of 39 people)
  • 40-49: 23.0% - (17 of 71 people)
  • 50-59: 21.0% - (15 of 70 people)
  • 60+: 26.0% - (8 of 30 people)

Most common drug interactions over time *:

< 1 month:
  • acute respiratory distress syndrome
  • anoxic encephalopathy
  • pulmonary embolism
  • vena cava thrombosis
  • dizziness
  • confusional state
  • clostridium difficile colitis
  • oral candidiasis
  • pneumonia
  • renal failure acute
1 - 6 months:
  • confusional state
  • dizziness
  • fatigue
  • hypertension
  • erectile dysfunction
  • haemarthrosis
  • encephalopathy
  • mental status changes
  • disorientation
  • hair loss
6 - 12 months:
  • chest pain
  • depression
  • fatigue
  • anaemia
  • anterior knee pain
  • arthroscopic surgery
  • back pain
  • feeling abnormal
  • gait abnormal
  • hip pain
1 - 2 years:
  • dizziness
  • leg pain
  • muscle weakness
  • sleeplessness
  • convulsion
  • erythema
  • leg cramps
  • muscle cramps
  • rigors
  • sweating - excessive
2 - 5 years:
  • pain
  • nausea
  • depression
  • pneumonia
  • anxiety
  • multiple sclerosis
  • hearing loss
  • tinnitus
  • weight decreased
  • diarrhoea
5 - 10 years:
  • red blood cell count decreased
  • pneumonia
  • hypoxia
  • depression
  • enlarged prostate
  • gallstones
  • herniated nucleus pulposus (slipped disk)
  • low back pain
  • neuropathy peripheral
  • renal cyst
10+ years:
  • swollen tongue
  • eczema eyelids
  • hyperkalaemia
  • swelling face
  • kidney crystallisation
  • chf
  • dysphagia
  • edema - peripheral, peripheral edema
  • paraplegia
  • renal insufficiency
not specified:
  • pain
  • fall
  • nausea
  • fatigue
  • headache
  • dyspnoea
  • depression
  • dizziness
  • asthenia
  • muscle spasms

Most common drug interactions by gender *:

female:
  • fall
  • nausea
  • fatigue
  • headache
  • pain
  • multiple sclerosis relapse
  • urinary tract infection
  • dyspnoea
  • dizziness
  • multiple sclerosis
male:
  • pain
  • depression
  • fatigue
  • anxiety
  • fall
  • nausea
  • muscle spasms
  • dyspnoea
  • dizziness
  • pain in extremity

Most common drug interactions by age *:

2-9:
  • vomiting
  • convulsion
  • muscular weakness
  • pneumonia
  • asthenia
  • nausea
  • multiple sclerosis
  • urinary tract infection
  • dehydration
  • pharyngitis streptococcal
10-19:
  • bradycardia
  • hypotension
  • hypothermia
  • nausea
  • respiratory depression
  • retching
  • salivary hypersecretion
  • asthenia
  • completed suicide
  • constipation
20-29:
  • multiple sclerosis
  • dyspnoea
  • pain
  • multiple sclerosis relapse
  • depression
  • insomnia
  • muscle spasms
  • contusion
  • nausea
  • influenza like illness
30-39:
  • depression
  • fatigue
  • headache
  • hypoaesthesia
  • multiple sclerosis relapse
  • muscle spasms
  • asthenia
  • multiple sclerosis
  • pain in extremity
  • dyspnoea
40-49:
  • nausea
  • pain
  • fatigue
  • headache
  • fall
  • multiple sclerosis relapse
  • depression
  • muscle spasms
  • asthenia
  • dyspnoea
50-59:
  • pain
  • fall
  • nausea
  • arthralgia
  • anxiety
  • dyspnoea
  • depression
  • diarrhoea
  • dizziness
  • urinary tract infection
60+:
  • fall
  • pain
  • fatigue
  • nausea
  • headache
  • urinary tract infection
  • dizziness
  • gait disturbance
  • asthenia
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasticity. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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