Review: taking Baclofen and Wellbutrin together


Summary

Drug interactions are reported among people who take Baclofen and Wellbutrin together. This review analyzes the effectiveness and drug interactions between Baclofen and Wellbutrin. It is created by eHealthMe based on reports of 1,228 people who take the same drugs from FDA and social media, and is updated regularly.

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Baclofen

Baclofen has active ingredients of baclofen. It is often used in muscle spasticity. (latest outcomes from Baclofen 28,487 users)

Wellbutrin

Wellbutrin has active ingredients of bupropion hydrochloride. It is often used in depression. (latest outcomes from Wellbutrin 60,004 users)

On Aug, 28, 2016

1,228 people who take Baclofen, Wellbutrin are studied.


Number of reports submitted per year:

Baclofen and Wellbutrin drug interactions.

Drug effectiveness over time:

Baclofen:
  • < 1 month: 22.0% - (2 of 9 people)
  • 1 - 6 months: 50.0% - (5 of 10 people)
  • 6 - 12 months: 0.0% - (0 of 5 people)
  • 1 - 2 years: 60.0% - (3 of 5 people)
  • 2 - 5 years: 50.0% - (4 of 8 people)
  • 5 - 10 years: 50.0% - (3 of 6 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Wellbutrin:
  • < 1 month: 0.0% - (0 of 6 people)
  • 1 - 6 months: 25.0% - (2 of 8 people)
  • 6 - 12 months: 20.0% - (1 of 5 people)
  • 1 - 2 years: 33.0% - (2 of 6 people)
  • 2 - 5 years: 16.0% - (2 of 12 people)
  • 5 - 10 years: 63.0% - (7 of 11 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Baclofen:
  • female: 50.0% - (19 of 38 people)
  • male: 10.0% - (1 of 10 people)
Wellbutrin:
  • female: 33.0% - (14 of 42 people)
  • male: 27.0% - (3 of 11 people)

Drug effectiveness by age:

Baclofen:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 40.0% - (2 of 5 people)
  • 30-39: 45.0% - (5 of 11 people)
  • 40-49: 30.0% - (3 of 10 people)
  • 50-59: 63.0% - (7 of 11 people)
  • 60+: 30.0% - (3 of 10 people)
Wellbutrin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 6 people)
  • 30-39: 50.0% - (6 of 12 people)
  • 40-49: 15.0% - (2 of 13 people)
  • 50-59: 36.0% - (4 of 11 people)
  • 60+: 50.0% - (5 of 10 people)

Most common drug interactions over time *:

< 1 month:
  • panic attack
  • chest tightness or pressure
  • rectal bleeding
  • back pain
  • chest pain
  • crying
  • depressed level of consciousness
  • depression
  • drug ineffective
  • dyskinesia
1 - 6 months:
  • anxiety
  • cholesterol
  • drug dependence
  • drug withdrawal syndrome
  • hair loss
  • high blood glucose level - infants
  • high blood pressure
  • pvc (premature ventricular contraction)
  • substance abuse
  • abnormal behaviour
6 - 12 months:
  • dizziness
  • insomnia
  • migraine
  • acne cystic
  • anxiety disorder
  • bad breath
  • chronic fatigue syndrome
  • chronic sinusitis
  • constipation
  • dry mouth
1 - 2 years:
  • insomnia
  • acne cystic
  • appetite - decreased
  • bad breath
  • chronic fatigue syndrome
  • chronic sinusitis
  • complicated migraine
  • constipation
  • depression aggravated
  • diarrhea
2 - 5 years:
  • constipation
  • acne cystic
  • bad breath
  • chronic fatigue syndrome
  • chronic sinusitis
  • insomnia
  • meniere's disease aggravated
  • nasal congestion
  • overactive bladder
  • anxiety disorder
5 - 10 years:
  • death
  • vulvar dysplasia
  • depression
  • high blood pressure
  • muscle spasms
  • pain
  • amnesia
  • anorexia
  • back pain
  • blood glucose decreased
10+ years:
  • perianal fungal infection
  • vomiting
  • fatigue - chronic
  • headache - migraine with aura
  • multiple sclerosis relapse
  • reflex sympathetic dystrophy
  • anxiety
  • bipolar disorder
  • cellulitis
  • depression
not specified:
  • fatigue
  • pain
  • fall
  • nausea
  • dyspnoea
  • depression
  • headache
  • anxiety
  • back pain
  • dizziness

Most common drug interactions by gender *:

female:
  • fatigue
  • dizziness
  • insomnia
  • fall
  • pain
  • dyspnoea
  • constipation
  • multiple sclerosis relapse
  • nausea
  • headache
male:
  • fatigue
  • depression
  • pain
  • nausea
  • anxiety
  • back pain
  • fall
  • constipation
  • dyspnoea
  • headache

Most common drug interactions by age *:

0-1:
  • activities of daily living impaired
  • anhedonia
  • anxiety
  • balance disorder
  • bronchitis
  • extrapyramidal disorder
  • injury
  • muscle spasms
  • myoclonus
  • neuropathy peripheral
2-9:
  • application site erythema
  • application site pain
  • application site pruritus
  • decreased interest
  • fatigue
  • headache
  • incontinence
  • insomnia
  • migraine
  • tinnitus
10-19:
  • bradycardia
  • respiratory arrest
  • grand mal convulsion
  • hypothermia
  • coma
  • suicidal ideation
  • vomiting
  • electroencephalogram abnormal
  • intentional overdose
  • overdose
20-29:
  • deep vein thrombosis
  • pulmonary embolism
  • pain
  • dyspnoea
  • gait disturbance
  • headache
  • injury
  • muscle spasticity
  • pneumonia
  • convulsion
30-39:
  • headache
  • fatigue
  • dyspnoea
  • nausea
  • pyrexia
  • completed suicide
  • constipation
  • depression
  • fall
  • muscle spasms
40-49:
  • constipation
  • insomnia
  • dizziness
  • fatigue
  • anxiety
  • tremor
  • pain
  • back pain
  • nausea
  • depression
50-59:
  • fall
  • fatigue
  • multiple sclerosis relapse
  • urinary tract infection
  • dyspnoea
  • muscle spasms
  • insomnia
  • pain
  • pain in extremity
  • gait disturbance
60+:
  • fall
  • gait disturbance
  • fatigue
  • asthenia
  • nausea
  • pain
  • pain in extremity
  • depression
  • dizziness
  • visual impairment

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Baclofen (baclofen) is often used to treat muscle spasticity. Wellbutrin (bupropion hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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