Review: taking Carafate and Nexium together


Summary

Drug interactions are reported among people who take Carafate and Nexium together. This review analyzes the effectiveness and drug interactions between Carafate and Nexium. It is created by eHealthMe based on reports of 1,271 people who take the same drugs from FDA and social media, and is updated regularly.

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Carafate

Carafate has active ingredients of sucralfate. It is often used in gastrooesophageal reflux disease. (latest outcomes from Carafate 5,212 users)

Nexium

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastrooesophageal reflux disease. (latest outcomes from Nexium 92,263 users)

On Aug, 30, 2016

1,271 people who take Carafate, Nexium are studied.


Number of reports submitted per year:

Carafate and Nexium drug interactions.

Drug effectiveness over time:

Carafate:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)
Nexium:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 66.0% - (2 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Carafate:
  • female: 28.0% - (2 of 7 people)
  • male: 25.0% - (1 of 4 people)
Nexium:
  • female: 42.0% - (3 of 7 people)
  • male: 25.0% - (1 of 4 people)

Drug effectiveness by age:

Carafate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 20.0% - (1 of 5 people)
  • 60+: 0.0% - (0 of 1 people)
Nexium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 25.0% - (1 of 4 people)
  • 60+: 100.0% - (2 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • urinary tract infection
  • renal failure acute
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • eosinophilia
  • metabolic acidosis
  • drug ineffective
  • amenorrhoea
  • liver injury
  • atrial fibrillation
1 - 6 months:
  • abdominal pain
  • dizziness
  • anxiety
  • arthritis
  • cardiac disorder
  • constipation
  • erectile dysfunction
  • gastrooesophageal reflux disease
  • hypersensitivity
  • nervousness
6 - 12 months:
  • osteoporosis
  • bone disorder
  • nausea
  • pancreatitis acute
  • weight increased
  • arthralgia
  • body height decreased
  • compression fracture
  • dyspepsia
  • fracture
1 - 2 years:
  • fatigue
  • osteoporosis
  • pain
  • anxiety
  • depression
  • arthritis
  • chest pain
  • multiple fractures
  • body height decreased
  • bone pain
2 - 5 years:
  • gastrooesophageal reflux disease
  • osteoporosis
  • arthritis
  • dyspepsia
  • pain
  • anxiety
  • bone disorder
  • drug ineffective
  • headache
  • scoliosis
5 - 10 years:
  • osteoporosis
  • hypertension
  • bone disorder
  • limb discomfort
  • vitamin d deficiency
  • abdominal pain upper
  • arthritis
  • fall
  • multiple fractures
  • muscle spasms
10+ years:
  • osteoporosis
  • arthritis
  • depression
  • fall
  • vitamin d deficiency
  • calcium deficiency
  • ankle fracture
  • bone pain
  • pain in extremity
  • arthropod bite
not specified:
  • pain
  • nausea
  • gastrooesophageal reflux disease
  • diarrhoea
  • osteoporosis
  • anxiety
  • vomiting
  • depression
  • fatigue
  • abdominal pain

Most common drug interactions by gender *:

female:
  • pain
  • osteoporosis
  • nausea
  • diarrhoea
  • depression
  • gastrooesophageal reflux disease
  • anxiety
  • fatigue
  • arthritis
  • abdominal pain
male:
  • pain
  • nausea
  • gastrooesophageal reflux disease
  • dyspepsia
  • dizziness
  • osteoporosis
  • vomiting
  • anxiety
  • diarrhoea
  • anaemia

Most common drug interactions by age *:

0-1:
  • anorexia
  • atrial fibrillation
  • confusional state
  • dyspnoea
  • hypotension
  • pneumonia
  • death
  • ejection fraction decreased
  • activities of daily living impaired
  • anhedonia
2-9:
  • tachypnoea
  • ascites
  • colitis
  • cystitis haemorrhagic
  • generalised oedema
  • hepatosplenomegaly
  • hyperglycaemia
  • hypoxia
  • lipase increased
  • lymphadenopathy
10-19:
  • cholecystitis chronic
  • abdominal pain
  • pain
  • biliary dyskinesia
  • diarrhoea
  • abdominal pain upper
  • vomiting
  • abdominal pain lower
  • alanine aminotransferase increased
  • ascites
20-29:
  • nausea
  • amenorrhoea
  • liver injury
  • cholecystitis chronic
  • abdominal pain
  • biliary dyskinesia
  • pain
  • anxiety
  • cholelithiasis
  • diarrhoea
30-39:
  • bronchitis
  • depression
  • blood cholesterol increased
  • blood alkaline phosphatase increased
  • abdominal pain upper
  • dizziness
  • cholelithiasis
  • anaemia
  • fall
  • nausea
40-49:
  • osteoporosis
  • arthritis
  • depression
  • bone disorder
  • chest pain
  • nausea
  • multiple fractures
  • abdominal pain upper
  • headache
  • osteoarthritis
50-59:
  • pain
  • gastrooesophageal reflux disease
  • osteoporosis
  • bone disorder
  • depression
  • fatigue
  • vomiting
  • nausea
  • diarrhoea
  • oedema peripheral
60+:
  • pain
  • diarrhoea
  • nausea
  • gastrooesophageal reflux disease
  • abdominal pain
  • hypotension
  • anxiety
  • anaemia
  • fall
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Carafate (sucralfate) is often used to treat gastrooesophageal reflux disease. Nexium (esomeprazole magnesium) is often used to treat gastrooesophageal reflux disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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