Review: taking Carafate and Nexium together


Summary

Drug interactions are reported among people who take Carafate and Nexium together. This review analyzes the effectiveness and drug interactions between Carafate and Nexium. It is created by eHealthMe based on reports of 1,647 people who take the same drugs from FDA and social media, and is updated regularly.

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Carafate

Carafate has active ingredients of sucralfate. It is often used in gastrooesophageal reflux disease. (latest outcomes from Carafate 6,685 users)

Nexium

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastrooesophageal reflux disease. (latest outcomes from Nexium 115,436 users)

On Sep, 15, 2016

1,647 people who take Carafate, Nexium are studied.


Number of reports submitted per year:

Carafate and Nexium drug interactions.

Drug effectiveness over time:

Carafate:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)
Nexium:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 66.0% - (2 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Carafate:
  • female: 28.0% - (2 of 7 people)
  • male: 25.0% - (1 of 4 people)
Nexium:
  • female: 42.0% - (3 of 7 people)
  • male: 25.0% - (1 of 4 people)

Drug effectiveness by age:

Carafate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 20.0% - (1 of 5 people)
  • 60+: 0.0% - (0 of 1 people)
Nexium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 33.0% - (1 of 3 people)
  • 50-59: 25.0% - (1 of 4 people)
  • 60+: 100.0% - (2 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • drug ineffective
  • urinary tract infection
  • hiatus hernia
  • renal failure acute
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • back pain
  • eosinophilia
  • metabolic acidosis
  • pneumonia
1 - 6 months:
  • gastrooesophageal reflux disease
  • abdominal pain
  • constipation
  • gastrointestinal haemorrhage
  • diarrhoea
  • drug ineffective
  • chest pain
  • depression
  • dizziness
  • irritable bowel syndrome
6 - 12 months:
  • osteoporosis
  • bone disorder
  • nausea
  • arthralgia
  • nephrolithiasis
  • pancreatitis acute
  • weight increased
  • body height decreased
  • compression fracture
  • dyspepsia
1 - 2 years:
  • pain
  • fatigue
  • body height decreased
  • dyspnoea
  • weight decreased
  • anxiety
  • depression
  • hiatus hernia
  • osteoporosis
  • adverse event
2 - 5 years:
  • osteoporosis
  • arthritis
  • gastrooesophageal reflux disease
  • pain
  • bone disorder
  • depression
  • drug ineffective
  • dyspepsia
  • asthma
  • osteoarthritis
5 - 10 years:
  • osteoporosis
  • disease recurrence
  • hypertension
  • malaise
  • pneumonia
  • fall
  • lung neoplasm malignant
  • malignant melanoma of sites other than skin
  • lower limb fracture
  • bone disorder
10+ years:
  • osteoporosis
  • arthritis
  • depression
  • fall
  • vitamin d deficiency
  • calcium deficiency
  • ankle fracture
  • bone pain
  • dyspepsia
  • pain in extremity
not specified:
  • pain
  • gastrooesophageal reflux disease
  • nausea
  • diarrhoea
  • vomiting
  • drug ineffective
  • osteoporosis
  • fatigue
  • anxiety
  • dyspnoea

Most common drug interactions by gender *:

female:
  • pain
  • gastrooesophageal reflux disease
  • nausea
  • diarrhoea
  • osteoporosis
  • depression
  • drug ineffective
  • fatigue
  • vomiting
  • anxiety
male:
  • pain
  • gastrooesophageal reflux disease
  • nausea
  • dyspepsia
  • dizziness
  • diarrhoea
  • vomiting
  • osteoporosis
  • weight decreased
  • pneumonia

Most common drug interactions by age *:

0-1:
  • anorexia
  • atrial fibrillation
  • confusional state
  • dyspnoea
  • hypotension
  • pneumonia
  • death
  • ejection fraction decreased
  • activities of daily living impaired
  • anhedonia
2-9:
  • tachypnoea
  • ascites
  • colitis
  • cystitis haemorrhagic
  • generalised oedema
  • hepatosplenomegaly
  • hyperglycaemia
  • hypoxia
  • lipase increased
  • lymphadenopathy
10-19:
  • abdominal pain
  • cholecystitis chronic
  • pain
  • biliary dyskinesia
  • diarrhoea
  • abdominal pain upper
  • vomiting
  • abdominal pain lower
  • alanine aminotransferase increased
  • ascites
20-29:
  • nausea
  • cholecystitis chronic
  • amenorrhoea
  • liver injury
  • anxiety
  • abdominal pain
  • biliary dyskinesia
  • pain
  • diarrhoea
  • weight decreased
30-39:
  • bronchitis
  • blood cholesterol increased
  • depression
  • blood alkaline phosphatase increased
  • abdominal pain upper
  • dizziness
  • cholelithiasis
  • nausea
  • pain in extremity
  • anaemia
40-49:
  • osteoporosis
  • arthritis
  • depression
  • pain
  • bone disorder
  • chest pain
  • nausea
  • back pain
  • fall
  • osteoarthritis
50-59:
  • gastrooesophageal reflux disease
  • drug ineffective
  • vomiting
  • pain
  • sinusitis
  • fatigue
  • headache
  • osteoporosis
  • diarrhoea
  • dyspnoea
60+:
  • pain
  • gastrooesophageal reflux disease
  • diarrhoea
  • nausea
  • vomiting
  • dyspnoea
  • hypotension
  • weight decreased
  • abdominal pain
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Carafate (sucralfate) is often used to treat gastrooesophageal reflux disease. Nexium (esomeprazole magnesium) is often used to treat gastrooesophageal reflux disease. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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