Review: taking Cefuroxime axetil and Methotrexate together


Drug interactions are reported among people who take Cefuroxime axetil and Methotrexate together. This review analyzes the effectiveness and drug interactions between Cefuroxime axetil and Methotrexate. It is created by eHealthMe based on reports of 81 people who take the same drugs from FDA and social media, and is updated regularly.

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Cefuroxime Axetil

Cefuroxime axetil has active ingredients of cefuroxime axetil. It is often used in sinusitis. (latest outcomes from Cefuroxime axetil 1,233 users)


Methotrexate has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate 212,463 users)

On Oct, 20, 2016

81 people who take Cefuroxime Axetil, Methotrexate are studied.

Number of reports submitted per year:

Cefuroxime axetil and Methotrexate drug interactions.

Most common drug interactions over time *:

< 1 month:
  • drug hypersensitivity
1 - 6 months:
  • swollen tongue
  • aphthous ulcer
  • dry mouth
  • femur fracture
  • lip ulceration
  • neuralgia
  • stomatitis
2 - 5 years:
  • bronchitis
  • intracranial aneurysm
  • lung neoplasm malignant
  • sinusitis
not specified:
  • sinusitis
  • oedema peripheral
  • diarrhoea
  • anaemia
  • pleural effusion
  • gastrooesophageal reflux disease
  • pain
  • abdominal pain
  • bone pain
  • pain in jaw

Most common drug interactions by gender *:

  • diarrhoea
  • sinusitis
  • oedema peripheral
  • pleural effusion
  • gastrooesophageal reflux disease
  • pain
  • abdominal pain
  • bone pain
  • pain in jaw
  • swelling
  • fall
  • oedema peripheral
  • abscess soft tissue
  • anxiety
  • comminuted fracture
  • dysstasia
  • femur fracture
  • fibula fracture
  • fracture nonunion
  • joint crepitation

Most common drug interactions by age *:

  • abdominal discomfort
  • abdominal pain
  • abdominal pain upper
  • biliary dyskinesia
  • cholecystitis chronic
  • cholesterosis
  • deep vein thrombosis
  • diarrhoea
  • faeces discoloured
  • hypokalaemia
  • atelectasis
  • acute prerenal failure
  • acute respiratory distress syndrome
  • cardiomegaly
  • dehydration
  • headache
  • interstitial lung disease
  • psoriasis
  • pulmonary oedema
  • rib fracture
  • oedema peripheral
  • sinusitis
  • bone pain
  • gastrooesophageal reflux disease
  • pain
  • pain in jaw
  • pleural effusion
  • tricuspid valve incompetence
  • appendicitis
  • aptyalism
  • nausea
  • sinusitis
  • back pain
  • oropharyngeal pain
  • vomiting
  • arthralgia
  • arthritis
  • cough
  • fall
  • femur fracture

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Cefuroxime axetil (cefuroxime axetil) is often used to treat sinusitis. Methotrexate (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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