Review: taking Celebrex and Cymbalta together


Summary

Drug interactions are reported among people who take Celebrex and Cymbalta together. This review analyzes the effectiveness and drug interactions between Celebrex and Cymbalta. It is created by eHealthMe based on reports of 1,523 people who take the same drugs from FDA and social media, and is updated regularly.

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Celebrex

Celebrex has active ingredients of celecoxib. It is often used in arthritis. (latest outcomes from Celebrex 73,546 users)

Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 48,467 users)

On Jul, 27, 2016

1,523 people who take Celebrex, Cymbalta are studied.


Number of reports submitted per year:

Celebrex and Cymbalta drug interactions.

Drug effectiveness over time:

Celebrex:
  • < 1 month: 14.0% - (1 of 7 people)
  • 1 - 6 months: 7.0% - (1 of 14 people)
  • 6 - 12 months: 33.0% - (6 of 18 people)
  • 1 - 2 years: 11.0% - (4 of 36 people)
  • 2 - 5 years: 33.0% - (9 of 27 people)
  • 5 - 10 years: 50.0% - (12 of 24 people)
  • 10+ years: 66.0% - (4 of 6 people)
  • not specified: 100.0% - (1 of 1 people)
Cymbalta:
  • < 1 month: 0.0% - (0 of 4 people)
  • 1 - 6 months: 22.0% - (4 of 18 people)
  • 6 - 12 months: 51.0% - (17 of 33 people)
  • 1 - 2 years: 18.0% - (4 of 22 people)
  • 2 - 5 years: 14.0% - (5 of 34 people)
  • 5 - 10 years: 55.0% - (5 of 9 people)
  • 10+ years: 80.0% - (4 of 5 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Celebrex:
  • female: 27.0% - (29 of 107 people)
  • male: 34.0% - (9 of 26 people)
Cymbalta:
  • female: 36.0% - (37 of 101 people)
  • male: 12.0% - (3 of 25 people)

Drug effectiveness by age:

Celebrex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 4 people)
  • 30-39: 9.0% - (1 of 11 people)
  • 40-49: 23.0% - (9 of 39 people)
  • 50-59: 34.0% - (16 of 47 people)
  • 60+: 37.0% - (12 of 32 people)
Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 10.0% - (1 of 10 people)
  • 40-49: 54.0% - (20 of 37 people)
  • 50-59: 25.0% - (12 of 48 people)
  • 60+: 18.0% - (5 of 27 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • anxiety
  • abdominal pain upper
  • diarrhoea
  • fall
  • muscular weakness
  • fatigue
  • pain
  • pyrexia
  • arthritis
1 - 6 months:
  • hepatic necrosis
  • hepatitis
  • pain
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • constipation
  • drug dependence
  • fall
  • pneumonia
  • depression
6 - 12 months:
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • drug dependence
  • hepatic necrosis
  • pneumonia
  • back pain
  • constipation
  • red face
  • drug withdrawal syndrome
  • pulmonary oedema
1 - 2 years:
  • red face
  • back pain
  • drug withdrawal syndrome
  • atrial fibrillation
  • coronary artery disease
  • thrombophlebitis
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • constipation
  • drug dependence
2 - 5 years:
  • diarrhea
  • gas - belching
  • kidney stones
  • vomiting
  • fall
  • fatigue
  • feeling abnormal
  • memory impairment
  • muscle twitching
  • swelling
5 - 10 years:
  • anxiety
  • depression
  • arthropathy
  • cerebral cyst
  • oral herpes
  • osteonecrosis
  • temporomandibular joint syndrome
  • vertigo
  • wound
  • aphthous stomatitis
10+ years:
  • carbohydrate craving
  • diabetes mellitus
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • heat cramps
  • itching scar
  • joint sprain
  • panic attack
  • petechiae
  • short-term memory loss
  • skin injury
not specified:
  • pain
  • nausea
  • anxiety
  • fall
  • depression
  • headache
  • fatigue
  • diarrhoea
  • anaemia
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • fall
  • diarrhoea
  • depression
  • headache
  • fatigue
  • constipation
  • anaemia
male:
  • pain
  • fall
  • back pain
  • chest pain
  • dyspnoea
  • depression
  • drug ineffective
  • anxiety
  • nausea
  • loss of consciousness

Most common drug interactions by age *:

0-1:
  • blood cholesterol increased
  • gallbladder operation
  • sensation of foreign body
  • type 2 diabetes mellitus
10-19:
  • headache
  • pain
  • aggression
  • agitation
  • anger
  • arthralgia
  • arthropathy
  • bone infarction
  • bone pain
  • colour blindness acquired
20-29:
  • anxiety
  • stupor
  • accidental death
  • arrhythmia
  • completed suicide
  • feeling abnormal
  • deep vein thrombosis
  • dyspnoea
  • obsessive thoughts
  • pain
30-39:
  • constipation
  • pneumonia
  • drug dependence
  • acute respiratory distress syndrome
  • coeliac artery compression syndrome
  • hepatic necrosis
  • nausea
  • weight increased
  • chest pain
  • drug withdrawal syndrome
40-49:
  • back pain
  • pain
  • fall
  • chest pain
  • dyspnoea
  • anxiety
  • fatigue
  • abdominal pain upper
  • diarrhoea
  • oedema peripheral
50-59:
  • pain
  • anxiety
  • nausea
  • diarrhoea
  • fall
  • anhedonia
  • osteonecrosis of jaw
  • anaemia
  • depression
  • spinal osteoarthritis
60+:
  • pain
  • nausea
  • anxiety
  • fatigue
  • depression
  • fall
  • headache
  • arthralgia
  • anaemia
  • constipation

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Celebrex (celecoxib) is often used to treat arthritis. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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