Review: taking Celexa and Lamictal xr together


Summary

Drug interactions are reported among people who take Celexa and Lamictal xr together. This review analyzes the effectiveness and drug interactions between Celexa and Lamictal xr. It is created by eHealthMe based on reports of 1,693 people who take the same drugs from FDA and social media, and is updated regularly.

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Celexa

Celexa has active ingredients of citalopram hydrobromide. It is often used in depression. (latest outcomes from Celexa 30,304 users)

Lamictal Xr

Lamictal xr has active ingredients of lamotrigine. It is often used in epilepsy. (latest outcomes from Lamictal xr 418 users)

On Jul, 21, 2016

1,693 people who take Celexa, Lamictal Xr are studied.


Number of reports submitted per year:

Celexa and Lamictal xr drug interactions.

Drug effectiveness over time:

Celexa:
  • < 1 month: 18.0% - (3 of 16 people)
  • 1 - 6 months: 25.0% - (7 of 27 people)
  • 6 - 12 months: 25.0% - (9 of 36 people)
  • 1 - 2 years: 22.0% - (9 of 40 people)
  • 2 - 5 years: 43.0% - (34 of 79 people)
  • 5 - 10 years: 48.0% - (20 of 41 people)
  • 10+ years: 15.0% - (3 of 19 people)
  • not specified: 40.0% - (2 of 5 people)
Lamictal Xr:
  • < 1 month: 10.0% - (1 of 10 people)
  • 1 - 6 months: 34.0% - (17 of 49 people)
  • 6 - 12 months: 35.0% - (12 of 34 people)
  • 1 - 2 years: 44.0% - (22 of 49 people)
  • 2 - 5 years: 62.0% - (42 of 67 people)
  • 5 - 10 years: 69.0% - (29 of 42 people)
  • 10+ years: 91.0% - (21 of 23 people)
  • not specified: 100.0% - (3 of 3 people)

Drug effectiveness by gender:

Celexa:
  • female: 32.0% - (65 of 199 people)
  • male: 34.0% - (22 of 64 people)
Lamictal Xr:
  • female: 50.0% - (107 of 210 people)
  • male: 59.0% - (40 of 67 people)

Drug effectiveness by age:

Celexa:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 17.0% - (5 of 29 people)
  • 20-29: 30.0% - (9 of 30 people)
  • 30-39: 28.0% - (25 of 88 people)
  • 40-49: 39.0% - (21 of 53 people)
  • 50-59: 36.0% - (15 of 41 people)
  • 60+: 54.0% - (12 of 22 people)
Lamictal Xr:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 59.0% - (19 of 32 people)
  • 20-29: 48.0% - (16 of 33 people)
  • 30-39: 57.0% - (52 of 90 people)
  • 40-49: 47.0% - (26 of 55 people)
  • 50-59: 60.0% - (24 of 40 people)
  • 60+: 37.0% - (10 of 27 people)

Most common drug interactions over time *:

< 1 month:
  • drug rash with eosinophilia and systemic symptoms
  • pyrexia
  • platelet count decreased
  • haemoglobin decreased
  • neutropenic sepsis
  • rash erythematous
  • vomiting
  • nerve injury
  • neutrophil count decreased
  • somnolence
1 - 6 months:
  • rash
  • asthenia
  • fatigue
  • blood creatine phosphokinase increased
  • facial paresis
  • myopathy
  • headache
  • stevens-johnson syndrome
  • fall
  • pyrexia
6 - 12 months:
  • rash
  • general physical health deterioration
  • hypotension
  • tachycardia
  • weight decreased
  • antipsychotic drug level increased
  • cachexia
  • hallucination, auditory
  • mental impairment
  • social avoidant behaviour
1 - 2 years:
  • drug toxicity
  • encephalitis
  • malaise
  • thyroiditis
  • dizziness
  • angioedema
  • deep vein thrombosis
  • deformity
  • depression
  • palpitations
2 - 5 years:
  • diabetes mellitus
  • short-term memory loss
  • neuropathy peripheral
  • nausea
  • dry mouth
  • anxiety
  • folliculitis
  • heart attack
  • restlessness
  • weakness
5 - 10 years:
  • convulsion
  • dizziness
  • memory impairment
  • cognitive disorder
  • dementia
  • drug ineffective
  • fatigue
  • headache
  • hypoaesthesia
  • nausea
10+ years:
  • acanthosis nigricans
  • cerebral palsy
  • dystonia
  • long-term memory loss
  • muscle spasticity
  • short-term memory loss
  • psychotic disorder
  • hallucination, visual
  • dexamethasone suppression test positive
  • insomnia
not specified:
  • somnolence
  • dizziness
  • vomiting
  • tremor
  • rash
  • depression
  • nausea
  • headache
  • fall
  • convulsion

Most common drug interactions by gender *:

female:
  • dizziness
  • rash
  • headache
  • somnolence
  • tremor
  • vomiting
  • pyrexia
  • nausea
  • fall
  • depression
male:
  • diabetes mellitus
  • vomiting
  • somnolence
  • nausea
  • depression
  • convulsion
  • rash
  • completed suicide
  • pyrexia
  • dizziness

Most common drug interactions by age *:

0-1:
  • blood triglycerides increased
  • breast cancer
  • diabetes mellitus
  • pancreatitis
2-9:
  • rash generalised
  • abnormal behaviour
  • convulsion
  • disinhibition
  • ecchymosis
  • prescribed overdose
  • rash papular
  • stevens johnson syndrome
10-19:
  • acanthosis nigricans
  • cerebral palsy
  • dystonia
  • long-term memory loss
  • muscle spasticity
  • short-term memory loss
  • completed suicide
  • lymphadenopathy
  • non-accidental overdose
  • pyrexia
20-29:
  • tremor
  • agitation
  • vomiting
  • dizziness
  • depressed level of consciousness
  • electrocardiogram qrs complex prolonged
  • electrocardiogram qt prolonged
  • metabolic acidosis
  • multiple drug overdose intentional
  • nystagmus
30-39:
  • rash
  • headache
  • hypotension
  • drug toxicity
  • dizziness
  • nausea
  • vomiting
  • malaise
  • cardiac arrest
  • general physical health deterioration
40-49:
  • drug rash with eosinophilia and systemic symptoms
  • somnolence
  • nerve injury
  • vomiting
  • suicide attempt
  • nausea
  • activated partial thromboplastin time prolonged
  • diabetes mellitus
  • headache
  • stevens-johnson syndrome
50-59:
  • anxiety
  • rash
  • completed suicide
  • confusional state
  • depression
  • fatigue
  • diabetes mellitus
  • somnolence
  • fall
  • dizziness
60+:
  • fall
  • haemoglobin decreased
  • neutropenic sepsis
  • platelet count decreased
  • rash erythematous
  • convulsion
  • pyrexia
  • neutrophil count decreased
  • dizziness
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Celexa (citalopram hydrobromide) is often used to treat depression. Lamictal xr (lamotrigine) is often used to treat epilepsy. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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