Review: taking Chantix and Cymbalta together


Summary

Drug interactions are reported among people who take Chantix and Cymbalta together. This review analyzes the effectiveness and drug interactions between Chantix and Cymbalta. It is created by eHealthMe based on reports of 1,481 people who take the same drugs from FDA and social media, and is updated regularly.

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Chantix

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. (latest outcomes from Chantix 69,328 users)

Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 58,912 users)

On Aug, 26, 2016

1,481 people who take Chantix, Cymbalta are studied.


Number of reports submitted per year:

Chantix and Cymbalta drug interactions.

Drug effectiveness over time:

Chantix:
  • < 1 month: 31.0% - (5 of 16 people)
  • 1 - 6 months: 52.0% - (9 of 17 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Cymbalta:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 40.0% - (2 of 5 people)
  • 6 - 12 months: 54.0% - (6 of 11 people)
  • 1 - 2 years: 50.0% - (6 of 12 people)
  • 2 - 5 years: 44.0% - (4 of 9 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 0.0% - (0 of 3 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Chantix:
  • female: 46.0% - (13 of 28 people)
  • male: 12.0% - (1 of 8 people)
Cymbalta:
  • female: 38.0% - (14 of 36 people)
  • male: 66.0% - (6 of 9 people)

Drug effectiveness by age:

Chantix:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 37.0% - (3 of 8 people)
  • 40-49: 36.0% - (4 of 11 people)
  • 50-59: 54.0% - (6 of 11 people)
  • 60+: 50.0% - (1 of 2 people)
Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 50.0% - (5 of 10 people)
  • 40-49: 42.0% - (6 of 14 people)
  • 50-59: 53.0% - (7 of 13 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • depression
  • anxiety
  • insomnia
  • abnormal dreams
  • agitation
  • feeling abnormal
  • headache
  • vomiting
  • malaise
1 - 6 months:
  • depression
  • anxiety
  • suicide attempt
  • intentional overdose
  • suicidal ideation
  • abnormal dreams
  • aggression
  • nausea
  • insomnia
  • irritability
6 - 12 months:
  • depression
  • anxiety
  • abnormal dreams
  • suicidal ideation
  • nausea
  • insomnia
  • aggression
  • suicide attempt
  • amnesia
  • fatigue
1 - 2 years:
  • depression
  • anxiety
  • suicide attempt
  • intentional overdose
  • headache
  • aggression
  • anger
  • nausea
  • suicidal ideation
  • emotional distress
2 - 5 years:
  • depression
  • anxiety
  • suicide attempt
  • aggression
  • insomnia
  • mental disorder
  • abnormal behaviour
  • amnesia
  • convulsion
  • disturbance in attention
5 - 10 years:
  • depression
  • anxiety
  • suicidal ideation
  • suicide attempt
  • intentional overdose
  • insomnia
  • irritability
  • mental disorder
  • aggression
  • anger
not specified:
  • nausea
  • depression
  • anxiety
  • abnormal dreams
  • insomnia
  • headache
  • fatigue
  • vomiting
  • pain
  • feeling abnormal

Most common drug interactions by gender *:

female:
  • nausea
  • depression
  • anxiety
  • abnormal dreams
  • headache
  • insomnia
  • fatigue
  • vomiting
  • feeling abnormal
  • suicidal ideation
male:
  • depression
  • anxiety
  • insomnia
  • nausea
  • pain
  • drug ineffective
  • suicide attempt
  • abnormal dreams
  • vomiting
  • dyspnoea

Most common drug interactions by age *:

0-1:
  • blood cholesterol increased
  • gallbladder operation
  • sensation of foreign body
  • type 2 diabetes mellitus
2-9:
  • abasia
  • arthralgia
  • bursitis
  • femur fracture
  • pain in extremity
  • stress fracture
  • cardiac disorder
10-19:
  • cholelithiasis
  • injury
  • pain
20-29:
  • depression
  • anxiety
  • suicide attempt
  • suicidal ideation
  • convulsion
  • panic disorder
  • intentional overdose
  • nausea
  • deep vein thrombosis
  • insomnia
30-39:
  • depression
  • anxiety
  • suicide attempt
  • suicidal ideation
  • insomnia
  • nausea
  • aggression
  • irritability
  • intentional overdose
  • agitation
40-49:
  • nausea
  • depression
  • anxiety
  • abnormal dreams
  • headache
  • insomnia
  • suicidal ideation
  • fatigue
  • loss of consciousness
  • stress
50-59:
  • depression
  • nausea
  • anxiety
  • headache
  • fatigue
  • abnormal dreams
  • insomnia
  • vomiting
  • feeling abnormal
  • suicide attempt
60+:
  • nausea
  • depression
  • anxiety
  • abnormal dreams
  • insomnia
  • vomiting
  • chronic obstructive pulmonary disease
  • weight decreased
  • nervousness
  • dyspnoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Chantix (varenicline tartrate) is often used to treat quit smoking. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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