Review: taking Cipro xr and Synthroid together


Summary

Drug interactions are reported among people who take Cipro xr and Synthroid together. This review analyzes the effectiveness and drug interactions between Cipro xr and Synthroid. It is created by eHealthMe based on reports of 295 people who take the same drugs from FDA and social media, and is updated regularly.

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Cipro Xr

Cipro xr has active ingredients of ciprofloxacin; ciprofloxacin hydrochloride.

Synthroid

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 92,389 users)

On Jul, 28, 2016

295 people who take Cipro Xr, Synthroid are studied.


Number of reports submitted per year:

Cipro xr and Synthroid drug interactions.

Drug effectiveness over time:

Cipro Xr:
  • < 1 month: 10.0% - (1 of 10 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Synthroid:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 50.0% - (1 of 2 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 75.0% - (3 of 4 people)
  • 10+ years: 100.0% - (3 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Cipro Xr:
  • female: 20.0% - (2 of 10 people)
  • male: 0.0% - (0 of 2 people)
Synthroid:
  • female: 66.0% - (8 of 12 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Cipro Xr:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 0.0% - (0 of 2 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 40.0% - (2 of 5 people)
Synthroid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 80.0% - (4 of 5 people)

Most common drug interactions over time *:

< 1 month:
  • urinary tract infection
  • international normalised ratio increased
  • jaundice
  • liver function test abnormal
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • confusional state
  • gamma-glutamyltransferase increased
  • pneumonia
  • blood alkaline phosphatase increased
1 - 6 months:
  • hypomagnesaemia
  • atrial fibrillation
  • diarrhoea
  • fall
  • hypothyroidism
  • subdural haematoma
6 - 12 months:
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood alkaline phosphatase increased
  • blood bilirubin increased
  • catheter related infection
  • diarrhoea
  • drug rash with eosinophilia and systemic symptoms
  • multi-organ failure
  • pseudomonas infection
  • renal failure acute
1 - 2 years:
  • feeling of despair
  • feelings of worthlessness
2 - 5 years:
  • feeling of despair
  • feelings of worthlessness
  • weakness
5 - 10 years:
  • anaemia
  • aortic valve stenosis
  • cardiac disorder
  • cerebrovascular accident
  • coarctation of the aorta
  • convulsion
  • coronary artery disease
  • dyspepsia
  • dysphagia
  • gastrointestinal disorder
not specified:
  • pain
  • nausea
  • arthralgia
  • anxiety
  • oedema peripheral
  • vomiting
  • injury
  • pyrexia
  • dizziness
  • fatigue

Most common drug interactions by gender *:

female:
  • pain
  • vomiting
  • arthralgia
  • oedema peripheral
  • anxiety
  • nausea
  • anaemia
  • dizziness
  • pain in extremity
  • dyspnoea
male:
  • international normalised ratio increased
  • urinary tract infection
  • nausea
  • arthralgia
  • jaundice
  • liver function test abnormal
  • fatigue
  • injury
  • oedema peripheral
  • pyrexia

Most common drug interactions by age *:

20-29:
  • deep vein thrombosis
  • oedema peripheral
  • thrombosis
  • pain
  • erythema
  • hypokalaemia
  • pain in extremity
  • post thrombotic syndrome
  • thrombophlebitis
  • adnexa uteri mass
30-39:
  • pain
  • gastroenteritis clostridial
  • nausea
  • vomiting
  • abdominal pain
  • abortion induced
  • anuria
  • c-reactive protein decreased
  • cholecystitis chronic
  • cholelithiasis
40-49:
  • arthralgia
  • nausea
  • pyrexia
  • vomiting
  • anxiety
  • headache
  • hypoaesthesia
  • muscular weakness
  • myalgia
  • pain
50-59:
  • dyspnoea
  • oedema peripheral
  • anxiety
  • nausea
  • arthralgia
  • pain
  • pyrexia
  • dizziness
  • vomiting
  • dysphagia
60+:
  • urinary tract infection
  • pain
  • fall
  • fatigue
  • vomiting
  • arthralgia
  • nausea
  • pneumonia
  • confusional state
  • oedema peripheral

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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