Review: taking Claritin and Coumadin together


Summary

Drug interactions are reported among people who take Claritin and Coumadin together. This review analyzes the effectiveness and drug interactions between Claritin and Coumadin. It is created by eHealthMe based on reports of 1,408 people who take the same drugs from FDA and social media, and is updated regularly.

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Claritin

Claritin has active ingredients of loratadine. It is often used in hypersensitivity. (latest outcomes from Claritin 22,301 users)

Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 73,270 users)

On Jul, 22, 2016

1,408 people who take Claritin, Coumadin are studied.


Number of reports submitted per year:

Claritin and Coumadin drug interactions.

Drug effectiveness over time:

Claritin:
  • < 1 month: 60.0% - (6 of 10 people)
  • 1 - 6 months: 33.0% - (1 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 25.0% - (1 of 4 people)
  • 2 - 5 years: 50.0% - (3 of 6 people)
  • 5 - 10 years: 40.0% - (2 of 5 people)
  • 10+ years: 71.0% - (5 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Coumadin:
  • < 1 month: 100.0% - (2 of 2 people)
  • 1 - 6 months: 50.0% - (4 of 8 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 60.0% - (3 of 5 people)
  • 2 - 5 years: 50.0% - (4 of 8 people)
  • 5 - 10 years: 100.0% - (5 of 5 people)
  • 10+ years: 100.0% - (6 of 6 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Claritin:
  • female: 60.0% - (14 of 23 people)
  • male: 33.0% - (4 of 12 people)
Coumadin:
  • female: 70.0% - (17 of 24 people)
  • male: 66.0% - (8 of 12 people)

Drug effectiveness by age:

Claritin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 33.0% - (3 of 9 people)
  • 50-59: 80.0% - (4 of 5 people)
  • 60+: 47.0% - (9 of 19 people)
Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 60.0% - (6 of 10 people)
  • 50-59: 60.0% - (3 of 5 people)
  • 60+: 78.0% - (15 of 19 people)

Most common drug interactions over time *:

< 1 month:
  • international normalised ratio increased
  • renal failure
  • infection
  • neutropenia
  • thrombocytopenia
  • tumour lysis syndrome
  • epistaxis
  • haemorrhage
  • somnolence
  • blood urine
1 - 6 months:
  • fatigue
  • oedema peripheral
  • drug ineffective
  • chest pain
  • erythema
  • febrile neutropenia
  • glossodynia
  • headache
  • hypoaesthesia oral
  • international normalised ratio decreased
6 - 12 months:
  • anxiety
  • diabetes mellitus
  • hepatitis c
  • hepatotoxicity
  • pain
  • gastrointestinal haemorrhage
  • malaise
  • blister
  • chills
  • dermatitis exfoliative
1 - 2 years:
  • diarrhoea
  • elevated mood
  • gallbladder cancer
  • hallucination
  • hypersomnia
2 - 5 years:
  • gallbladder disorder
  • mental disorder
  • pain
  • cholecystitis
  • cholecystitis chronic
  • elevated mood
  • haematuria
  • hypersomnia
  • skin - dry
5 - 10 years:
  • arthralgia
  • atrial fibrillation
  • blood urine
  • hallucination
  • headache
  • international normalised ratio increased
  • thrombosis
10+ years:
  • hives
  • itching
  • rash generalised
  • urticaria
  • gingival bleeding
  • haemoglobin decreased
  • international normalised ratio increased
  • occult blood positive
  • dizziness
  • abdominal discomfort
not specified:
  • pain
  • dyspnoea
  • anxiety
  • fatigue
  • nausea
  • depression
  • arthralgia
  • asthenia
  • dizziness
  • oedema peripheral

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • depression
  • dyspnoea
  • arthralgia
  • oedema peripheral
  • asthenia
  • cough
  • fatigue
  • osteonecrosis of jaw
male:
  • pain
  • dyspnoea
  • fatigue
  • nausea
  • anxiety
  • dizziness
  • asthenia
  • arthralgia
  • depression
  • international normalised ratio increased

Most common drug interactions by age *:

2-9:
  • anxiety
  • death
  • depression
  • fear
  • injury
  • multi-organ failure
  • pain
  • renal failure
10-19:
  • arthralgia
  • decreased appetite
  • dry skin
  • erythema
  • fatigue
  • headache
  • hypokalaemia
  • oral discomfort
  • pain of skin
  • paraesthesia oral
20-29:
  • drug ineffective
  • red cell aplasia
  • cardiac disorder
  • migraine
  • pain
  • type 1 diabetes mellitus
  • gallbladder disorder
  • mental disorder
  • cardiac failure congestive
  • diabetes mellitus
30-39:
  • dyskinesia
  • anxiety
  • depression
  • pain
  • dysphagia
  • anhedonia
  • fatigue
  • speech disorder
  • type 2 diabetes mellitus
  • alanine aminotransferase increased
40-49:
  • pain
  • depression
  • left ventricular hypertrophy
  • cataract
  • cough
  • arthralgia
  • pain in extremity
  • back pain
  • musculoskeletal chest pain
  • vitreous floaters
50-59:
  • pain
  • anxiety
  • arthralgia
  • depression
  • osteonecrosis of jaw
  • oedema peripheral
  • neuropathy peripheral
  • deformity
  • dental caries
  • emotional distress
60+:
  • dyspnoea
  • anxiety
  • dizziness
  • atrial fibrillation
  • asthenia
  • pain
  • fatigue
  • nausea
  • cardiac failure congestive
  • international normalised ratio increased

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Claritin (loratadine) is often used to treat hypersensitivity. Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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