Review: taking Claritin and Zyrtec together


Summary

Drug interactions are reported among people who take Claritin and Zyrtec together. This review analyzes the effectiveness and drug interactions between Claritin and Zyrtec. It is created by eHealthMe based on reports of 2,046 people who take the same drugs from FDA and social media, and is updated regularly.

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Claritin

Claritin has active ingredients of loratadine. It is often used in hypersensitivity. (latest outcomes from Claritin 38,014 users)

Zyrtec

Zyrtec has active ingredients of cetirizine hydrochloride. It is often used in hypersensitivity. (latest outcomes from Zyrtec 46,713 users)

On Sep, 12, 2016

2,046 people who take Claritin, Zyrtec are studied.


Number of reports submitted per year:

Claritin and Zyrtec drug interactions.

Drug effectiveness over time:

Claritin:
  • < 1 month: 27.0% - (5 of 18 people)
  • 1 - 6 months: 14.0% - (1 of 7 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 22.0% - (2 of 9 people)
  • 5 - 10 years: 25.0% - (1 of 4 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)
Zyrtec:
  • < 1 month: 16.0% - (2 of 12 people)
  • 1 - 6 months: 20.0% - (2 of 10 people)
  • 6 - 12 months: 57.0% - (4 of 7 people)
  • 1 - 2 years: 50.0% - (2 of 4 people)
  • 2 - 5 years: 50.0% - (3 of 6 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Claritin:
  • female: 27.0% - (8 of 29 people)
  • male: 21.0% - (4 of 19 people)
Zyrtec:
  • female: 37.0% - (10 of 27 people)
  • male: 29.0% - (5 of 17 people)

Drug effectiveness by age:

Claritin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 5 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 12.0% - (1 of 8 people)
  • 30-39: 20.0% - (2 of 10 people)
  • 40-49: 41.0% - (7 of 17 people)
  • 50-59: 66.0% - (2 of 3 people)
  • 60+: 0.0% - (0 of 3 people)
Zyrtec:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 20.0% - (1 of 5 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 28.0% - (2 of 7 people)
  • 30-39: 20.0% - (2 of 10 people)
  • 40-49: 53.0% - (8 of 15 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 33.0% - (1 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • loss of consciousness
  • drug ineffective
  • urticaria
  • abnormal behaviour
  • blood pressure increased
  • mental disorder
  • hallucination
  • headache
  • fatigue
1 - 6 months:
  • hypertension
  • liver disorder
  • dehydration
  • electrocardiogram qt prolonged
  • fatigue
  • insomnia
  • lacunar infarction
  • rash
  • reflux oesophagitis
  • small intestine carcinoma
6 - 12 months:
  • constipation
  • pain
  • haemorrhoids
  • fatigue
  • lacunar infarction
  • liver disorder
  • reflux oesophagitis
  • gastrooesophageal reflux disease
  • hypokalaemia
  • renal failure chronic
1 - 2 years:
  • anxiety
  • muscle pain
  • pain - joints
  • tic
  • adverse event
  • constipation
  • deep vein thrombosis
  • depression
  • fatigue
  • femur fracture
2 - 5 years:
  • anxiety
  • back pain
  • biliary dyskinesia
  • deep vein thrombosis
  • dehydration
  • depression
  • drug effect increased
  • gait disturbance
  • mental disorder
  • pain
5 - 10 years:
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • frequent headaches
  • nausea
  • pain - joints
  • stomach pain
  • tennis elbow
  • upset stomach
  • anxiety
  • arthralgia
  • biopsy breast abnormal
10+ years:
  • abnormal behaviour
  • aggression
  • amnesia
  • anxiety
  • delusion
  • depression
  • hallucination
  • insomnia
  • irritability
  • paranoia
not specified:
  • drug ineffective
  • pain
  • fatigue
  • anxiety
  • nausea
  • depression
  • dyspnoea
  • diarrhoea
  • headache
  • arthralgia

Most common drug interactions by gender *:

female:
  • pain
  • drug ineffective
  • nausea
  • fatigue
  • anxiety
  • depression
  • sinusitis
  • dyspnoea
  • arthralgia
  • headache
male:
  • drug ineffective
  • fatigue
  • dizziness
  • depression
  • dyspnoea
  • anxiety
  • asthenia
  • pain
  • diarrhoea
  • back pain

Most common drug interactions by age *:

0-1:
  • alopecia
  • blood pressure increased
  • congenital oral malformation
  • fall
  • foetal exposure during pregnancy
  • photosensitivity reaction
  • psychomotor hyperactivity
  • syncope
2-9:
  • drug ineffective
  • somnolence
  • anxiety
  • epistaxis
  • muscle pain
  • pain - joints
  • tic
  • feeling abnormal
  • drug hypersensitivity
  • epstein-barr virus associated lymphoproliferative disorder
10-19:
  • pain
  • fatigue
  • somnolence
  • suicidal ideation
  • mental disorder
  • nausea
  • anxiety
  • depression
  • headache
  • rash
20-29:
  • cholelithiasis
  • pain
  • anxiety
  • depression
  • loss of consciousness
  • pulmonary embolism
  • headache
  • cholecystitis
  • cholecystitis chronic
  • injury
30-39:
  • fatigue
  • bronchitis
  • abdominal pain
  • fall
  • arthralgia
  • blood cholesterol increased
  • contusion
  • depression
  • pain in extremity
  • pruritus
40-49:
  • back pain
  • pain
  • depression
  • dyspnoea
  • drug ineffective
  • sinusitis
  • cough
  • pain in extremity
  • headache
  • fatigue
50-59:
  • nausea
  • fatigue
  • anxiety
  • depression
  • diarrhoea
  • pyrexia
  • arthralgia
  • vomiting
  • constipation
  • pain
60+:
  • nausea
  • diarrhoea
  • pain
  • dizziness
  • drug ineffective
  • anxiety
  • vomiting
  • dyspnoea
  • fatigue
  • cardiac failure congestive

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Claritin (loratadine) is often used to treat hypersensitivity. Zyrtec (cetirizine hydrochloride) is often used to treat hypersensitivity. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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