Review: taking Clonazepam and Zopiclone together


Summary

Drug interactions are reported among people who take Clonazepam and Zopiclone together. This review analyzes the effectiveness and drug interactions between Clonazepam and Zopiclone. It is created by eHealthMe based on reports of 1,053 people who take the same drugs from FDA and social media, and is updated regularly.

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Clonazepam

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. (latest outcomes from Clonazepam 39,945 users)

Zopiclone

Zopiclone has active ingredients of eszopiclone. It is often used in insomnia. (latest outcomes from Zopiclone 6,571 users)

On Jul, 27, 2016

1,053 people who take Clonazepam, Zopiclone are studied.


Number of reports submitted per year:

Clonazepam and Zopiclone drug interactions.

Drug effectiveness over time:

Clonazepam:
  • < 1 month: 30.0% - (4 of 13 people)
  • 1 - 6 months: 22.0% - (5 of 22 people)
  • 6 - 12 months: 46.0% - (6 of 13 people)
  • 1 - 2 years: 72.0% - (8 of 11 people)
  • 2 - 5 years: 42.0% - (8 of 19 people)
  • 5 - 10 years: 64.0% - (11 of 17 people)
  • 10+ years: 44.0% - (4 of 9 people)
  • not specified: 50.0% - (1 of 2 people)
Zopiclone:
  • < 1 month: 12.0% - (2 of 16 people)
  • 1 - 6 months: 38.0% - (10 of 26 people)
  • 6 - 12 months: 60.0% - (6 of 10 people)
  • 1 - 2 years: 64.0% - (9 of 14 people)
  • 2 - 5 years: 50.0% - (10 of 20 people)
  • 5 - 10 years: 38.0% - (5 of 13 people)
  • 10+ years: 33.0% - (1 of 3 people)
  • not specified: 50.0% - (1 of 2 people)

Drug effectiveness by gender:

Clonazepam:
  • female: 41.0% - (31 of 75 people)
  • male: 51.0% - (16 of 31 people)
Zopiclone:
  • female: 42.0% - (32 of 75 people)
  • male: 41.0% - (12 of 29 people)

Drug effectiveness by age:

Clonazepam:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 50.0% - (6 of 12 people)
  • 30-39: 47.0% - (11 of 23 people)
  • 40-49: 40.0% - (12 of 30 people)
  • 50-59: 51.0% - (15 of 29 people)
  • 60+: 27.0% - (3 of 11 people)
Zopiclone:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 54.0% - (6 of 11 people)
  • 30-39: 34.0% - (8 of 23 people)
  • 40-49: 34.0% - (10 of 29 people)
  • 50-59: 48.0% - (14 of 29 people)
  • 60+: 45.0% - (5 of 11 people)

Most common drug interactions over time *:

< 1 month:
  • insomnia
  • drug ineffective
  • dysgeusia
  • initial insomnia
  • middle insomnia
  • somnolence
  • headache
  • dizziness
  • anxiety
  • agitation
1 - 6 months:
  • drug ineffective
  • dysgeusia
  • insomnia
  • abnormal dreams
  • anxiety
  • aggression
  • alopecia
  • disturbance in attention
  • emotional disorder
  • initial insomnia
6 - 12 months:
  • insomnia
  • fatigue
  • initial insomnia
  • abnormal dreams
  • agoraphobia
  • anxiety aggravated
  • daydreaming
  • depressed mood
  • depression
  • drowsiness
1 - 2 years:
  • nausea
  • depression
  • insomnia
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • emotional distress
  • fatigue
  • headache
  • hypersexuality
  • joint pain
  • joint swelling
2 - 5 years:
  • migraine
  • nausea
  • cellulitis
  • gastric disorder
  • urinary retention
  • anxiety
  • anxiety aggravated
  • anxiety disorder
  • blood triglycerides increased
  • calculus ureteric
5 - 10 years:
  • dry mouth
  • fatigue
  • anxiety, apprehension, feeling uptight, jitters, stress, stress and anxiety, tension
  • depression post-operative
  • headache
  • insomnia
  • joint pain
  • joint swelling
  • nausea
  • constipation
10+ years:
  • abdominal pain
  • abdominal bloating
  • weight increased
  • cancer pain
  • cholelithiasis
  • gallbladder disorder
  • mental disorder
  • tiredness
not specified:
  • insomnia
  • drug ineffective
  • depression
  • anxiety
  • weight increased
  • headache
  • fatigue
  • diabetes mellitus
  • pain
  • dyspnoea

Most common drug interactions by gender *:

female:
  • insomnia
  • drug ineffective
  • anxiety
  • headache
  • fatigue
  • pain
  • dysgeusia
  • dyspnoea
  • dizziness
  • abdominal pain
male:
  • insomnia
  • drug ineffective
  • depression
  • suicidal ideation
  • weight increased
  • anxiety
  • type 2 diabetes mellitus
  • fall
  • somnolence
  • headache

Most common drug interactions by age *:

10-19:
  • anxiety
  • depression
  • insomnia
  • abdominal pain
  • alcohol use
  • apnoea
  • back pain
  • cholecystitis chronic
  • cholelithiasis
  • drug ineffective
20-29:
  • abdominal pain upper
  • abdominal pain
  • muscle spasms
  • drug abuse
  • joint sprain
  • suicidal ideation
  • vaginal discharge
  • chest discomfort
  • dyspnoea
  • asthenia
30-39:
  • drug ineffective
  • anxiety
  • weight increased
  • insomnia
  • dizziness
  • diabetes mellitus
  • overdose
  • decreased appetite
  • nausea
  • depression
40-49:
  • insomnia
  • drug ineffective
  • dysgeusia
  • weight increased
  • headache
  • fatigue
  • type 2 diabetes mellitus
  • chest pain
  • depression
  • diabetes mellitus
50-59:
  • insomnia
  • drug ineffective
  • fatigue
  • nausea
  • anxiety
  • dysgeusia
  • depression
  • dyspnoea
  • headache
  • agitation
60+:
  • insomnia
  • drug ineffective
  • middle insomnia
  • fatigue
  • pain
  • headache
  • pain in extremity
  • anxiety
  • dizziness
  • somnolence

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Clonazepam (clonazepam) is often used to treat stress and anxiety. Zopiclone (eszopiclone) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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