Review: taking Clonidine and Sertraline together


Summary

Drug interactions are reported among people who take Clonidine and Sertraline together. This review analyzes the effectiveness and drug interactions between Clonidine and Sertraline. It is created by eHealthMe based on reports of 1,873 people who take the same drugs from FDA and social media, and is updated regularly.

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Clonidine

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. (latest outcomes from Clonidine 29,481 users)

Sertraline

Sertraline has active ingredients of sertraline hydrochloride. It is often used in depression. (latest outcomes from Sertraline 46,905 users)

On Sep, 17, 2016

1,873 people who take Clonidine, Sertraline are studied.


Number of reports submitted per year:

Clonidine and Sertraline drug interactions.

Drug effectiveness over time:

Clonidine:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 36.0% - (4 of 11 people)
  • 6 - 12 months: 33.0% - (3 of 9 people)
  • 1 - 2 years: 40.0% - (2 of 5 people)
  • 2 - 5 years: 12.0% - (1 of 8 people)
  • 5 - 10 years: 63.0% - (7 of 11 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 33.0% - (1 of 3 people)
Sertraline:
  • < 1 month: 0.0% - (0 of 4 people)
  • 1 - 6 months: 23.0% - (4 of 17 people)
  • 6 - 12 months: 0.0% - (0 of 8 people)
  • 1 - 2 years: 66.0% - (2 of 3 people)
  • 2 - 5 years: 35.0% - (5 of 14 people)
  • 5 - 10 years: 20.0% - (1 of 5 people)
  • 10+ years: 75.0% - (6 of 8 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Clonidine:
  • female: 38.0% - (13 of 34 people)
  • male: 38.0% - (8 of 21 people)
Sertraline:
  • female: 29.0% - (11 of 37 people)
  • male: 31.0% - (7 of 22 people)

Drug effectiveness by age:

Clonidine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 33.0% - (1 of 3 people)
  • 10-19: 28.0% - (6 of 21 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 71.0% - (5 of 7 people)
  • 50-59: 72.0% - (8 of 11 people)
  • 60+: 0.0% - (0 of 5 people)
Sertraline:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 33.0% - (1 of 3 people)
  • 10-19: 21.0% - (4 of 19 people)
  • 20-29: 20.0% - (1 of 5 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 50.0% - (4 of 8 people)
  • 50-59: 50.0% - (6 of 12 people)
  • 60+: 16.0% - (1 of 6 people)

Most common drug interactions over time *:

< 1 month:
  • vomiting
  • maternal exposure during pregnancy
  • somnolence
  • abortion spontaneous
  • anxiety
  • nausea
  • tremor
  • irritability
  • pallor
  • syncope
1 - 6 months:
  • somnolence
  • memory impairment
  • vomiting
  • anxiety aggravated
  • depression aggravated
  • dizziness aggravated
  • insomnia exacerbated
  • maternal exposure during pregnancy
  • night sweats
  • vertigo
6 - 12 months:
  • aggression aggravated
  • anxiety aggravated
  • blood cholesterol increased
  • cerebrovascular accident
  • fall
  • hyperlipidaemia
  • muscle twitching
  • obesity
  • simple partial seizures
  • type 2 diabetes mellitus
1 - 2 years:
  • nausea
  • drug ineffective
  • gynaecomastia
  • insomnia
  • mastitis
  • aggression
  • anxiety aggravated
  • blood glucose increased
  • constipation
  • depressed mood
2 - 5 years:
  • dizziness
  • breast cancer female
  • breast cyst
  • postoperative wound complication
  • anxiety aggravated
  • depression aggravated
  • dizziness aggravated
  • insomnia exacerbated
  • memory impairment
  • musculoskeletal discomfort
5 - 10 years:
  • deep vein thrombosis
  • coronary artery disease
  • drug ineffective
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • nipple discharge - abnormal
  • pulmonary embolism
  • simple partial seizures
  • acne cystic
  • allergies
  • angina pectoris
10+ years:
  • diabetes mellitus
  • diabetic ketoacidosis
  • pancreatitis
  • shock
  • tardive dyskinesia
  • affective disorder
  • autism spectrum disorder
  • constipation
  • convulsion
  • obsessive-compulsive disorder
not specified:
  • nausea
  • anxiety
  • pain
  • dyspnoea
  • depression
  • headache
  • vomiting
  • dizziness
  • fatigue
  • back pain

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • anxiety
  • depression
  • dyspnoea
  • headache
  • vomiting
  • arthralgia
  • injury
  • fall
male:
  • anxiety
  • dizziness
  • headache
  • pain
  • back pain
  • nausea
  • tremor
  • dyspnoea
  • diarrhoea
  • fatigue

Most common drug interactions by age *:

0-1:
  • anxiety
  • aortic valve disease mixed
  • attention deficit/hyperactivity disorder
  • cardiac murmur
  • deafness
  • depression
  • developmental delay
  • diabetes mellitus
  • diabetic ketoacidosis
  • foetal exposure during pregnancy
2-9:
  • weight increased
  • dyspnoea
  • aggression
  • dizziness
  • dysstasia
  • eye movement disorder
  • gastric dilatation
  • attention deficit/hyperactivity disorder
  • drug ineffective
  • enuresis
10-19:
  • aggression
  • anxiety
  • irritability
  • suicidal ideation
  • agitation
  • weight increased
  • diabetic ketoacidosis
  • abnormal behaviour
  • gynaecomastia
  • drug ineffective
20-29:
  • nausea
  • vomiting
  • malaise
  • anxiety
  • abdominal pain
  • dizziness
  • headache
  • cerebrovascular accident
  • renal failure acute
  • convulsion
30-39:
  • dyspnoea
  • anxiety
  • headache
  • back pain
  • hypertension
  • nausea
  • depression
  • abdominal pain
  • vomiting
  • diabetes mellitus
40-49:
  • pain
  • nausea
  • anxiety
  • depression
  • headache
  • back pain
  • diarrhoea
  • dyspnoea
  • arthralgia
  • injury
50-59:
  • pain
  • nausea
  • oedema peripheral
  • anxiety
  • depression
  • arthralgia
  • fall
  • dyspnoea
  • anaemia
  • fatigue
60+:
  • nausea
  • hypotension
  • hypertension
  • headache
  • diarrhoea
  • vomiting
  • pneumonia
  • dyspnoea
  • fall
  • pain

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Clonidine (clonidine) is often used to treat high blood pressure. Sertraline (sertraline hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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