Review: taking Cordarone and Lopressor together


Summary

Drug interactions are reported among people who take Cordarone and Lopressor together. This review analyzes the effectiveness and drug interactions between Cordarone and Lopressor. It is created by eHealthMe based on reports of 2,525 people who take the same drugs from FDA and social media, and is updated regularly.

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Cordarone

Cordarone has active ingredients of amiodarone hydrochloride. It is often used in atrial fibrillation/flutter. (latest outcomes from Cordarone 12,890 users)

Lopressor

Lopressor has active ingredients of metoprolol tartrate. It is often used in high blood pressure. (latest outcomes from Lopressor 19,899 users)

On Aug, 24, 2016

2,525 people who take Cordarone, Lopressor are studied.


Number of reports submitted per year:

Cordarone and Lopressor drug interactions.

Drug effectiveness over time:

Cordarone:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 66.0% - (2 of 3 people)
  • 1 - 2 years: 62.0% - (5 of 8 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 25.0% - (1 of 4 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 1 people)
Lopressor:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 20.0% - (1 of 5 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 16.0% - (1 of 6 people)
  • 2 - 5 years: 50.0% - (3 of 6 people)
  • 5 - 10 years: 25.0% - (1 of 4 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Cordarone:
  • female: 60.0% - (6 of 10 people)
  • male: 33.0% - (7 of 21 people)
Lopressor:
  • female: 50.0% - (5 of 10 people)
  • male: 27.0% - (6 of 22 people)

Drug effectiveness by age:

Cordarone:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 39.0% - (11 of 28 people)
Lopressor:
  • 0-1: 0.0% - (0 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 50.0% - (1 of 2 people)
  • 60+: 34.0% - (10 of 29 people)

Most common drug interactions over time *:

< 1 month:
  • renal failure
  • pain
  • injury
  • anxiety
  • emotional distress
  • fear
  • renal injury
  • death
  • multi-organ failure
  • anhedonia
1 - 6 months:
  • rhabdomyolysis
  • fatigue
  • urinary tract infection
  • dehydration
  • bradycardia
  • dizziness
  • dyspnoea
  • asthenia
  • atrial fibrillation
  • torsade de pointes
6 - 12 months:
  • alopecia
  • dyspnoea
  • anxiety
  • drug ineffective
  • eczema
  • insomnia
  • anhedonia
  • asthenia
  • body temperature increased
  • brugada syndrome
1 - 2 years:
  • lightheadedness - fainting
  • nervousness
  • shortness of breath
  • swelling of the ankles - feet - legs
  • asthenia
  • hypotension
  • bradycardia
  • pain
  • anxiety
  • coronary artery disease
2 - 5 years:
  • renal failure
  • bradycardia
  • dizziness
  • dyspnoea
  • erectile dysfunction
  • angina pectoris
  • aphasia
  • drug level increased
  • headache
  • hepatic failure
5 - 10 years:
  • erectile dysfunction
  • asthenia
  • atrioventricular block
  • blood ph decreased
  • blood ph increased
  • bradycardia
  • cardiac failure
  • concomitant disease progression
  • confusion
  • disseminated intravascular coagulation
10+ years:
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • dermatomyositis
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fungal infection
  • lack of strength, muscle weakness, weakness
  • lower blood pressure
  • muscle necrosis
  • rhabdomyolysis
  • acute respiratory failure
not specified:
  • pain
  • atrial fibrillation
  • renal failure
  • anxiety
  • injury
  • dyspnoea
  • cardiac failure congestive
  • nausea
  • asthenia
  • hypotension

Most common drug interactions by gender *:

female:
  • pain
  • atrial fibrillation
  • anxiety
  • cardiac failure congestive
  • dyspnoea
  • renal failure
  • asthenia
  • injury
  • nausea
  • renal failure acute
male:
  • pain
  • renal failure
  • atrial fibrillation
  • anxiety
  • injury
  • dyspnoea
  • hypotension
  • emotional distress
  • nausea
  • fear

Most common drug interactions by age *:

0-1:
  • atrial fibrillation
  • blood pressure decreased
  • dysphagia
  • glossodynia
  • lip swelling
  • pancytopenia
  • pharyngolaryngeal pain
  • white blood cell count decreased
2-9:
  • hypertension
  • abdominal distension
  • abdominal pain
  • abnormal behaviour
  • acrochordon
  • amnesia
  • anaemia
  • animal bite
  • anogenital warts
  • arrhythmia
10-19:
  • ascites
  • cataract
  • chest discomfort
  • clostridial infection
  • ear discomfort
  • eye haemorrhage
  • fall
  • gingival bleeding
  • haemorrhoidal haemorrhage
  • headache
20-29:
  • ventricular tachycardia
  • renal failure
  • ventricular extrasystoles
  • atrial fibrillation
  • dyspnoea
  • cardiac failure congestive
  • influenza like illness
  • injury
  • mass
  • multi-organ failure
30-39:
  • confusional state
  • cardiogenic shock
  • hypotension
  • renal failure
  • pain
  • cardiac arrest
  • dyspnoea
  • anxiety
  • stress
  • multiple drug overdose
40-49:
  • renal failure
  • pain
  • atrial fibrillation
  • arrhythmia
  • cardiac arrest
  • ventricular fibrillation
  • anxiety
  • hypertension
  • hypotension
  • injury
50-59:
  • pain
  • renal failure
  • anxiety
  • atrial fibrillation
  • injury
  • dyspnoea
  • nausea
  • oedema peripheral
  • asthenia
  • emotional distress
60+:
  • pain
  • atrial fibrillation
  • renal failure
  • anxiety
  • injury
  • dyspnoea
  • cardiac failure congestive
  • emotional distress
  • hypotension
  • nausea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Cordarone (amiodarone hydrochloride) is often used to treat atrial fibrillation/flutter. Lopressor (metoprolol tartrate) is often used to treat high blood pressure. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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