Review: taking Coumadin and Cipro together


Summary

Drug interactions are reported among people who take Coumadin and Cipro together. This review analyzes the effectiveness and drug interactions between Coumadin and Cipro. It is created by eHealthMe based on reports of 1,099 people who take the same drugs from FDA and social media, and is updated regularly.

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Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 80,735 users)

Cipro

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. (latest outcomes from Cipro 15,916 users)

On Aug, 19, 2016

1,099 people who take Coumadin, Cipro are studied.


Number of reports submitted per year:

Coumadin and Cipro drug interactions.

Drug effectiveness over time:

Coumadin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 33.0% - (1 of 3 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (2 of 2 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (3 of 3 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Cipro:
  • < 1 month: 40.0% - (2 of 5 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Coumadin:
  • female: 80.0% - (4 of 5 people)
  • male: 60.0% - (3 of 5 people)
Cipro:
  • female: 50.0% - (2 of 4 people)
  • male: 25.0% - (1 of 4 people)

Drug effectiveness by age:

Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 2 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 83.0% - (5 of 6 people)
Cipro:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 37.0% - (3 of 8 people)

Most common drug interactions over time *:

< 1 month:
  • international normalised ratio increased
  • hypotension
  • constipation
  • haemorrhage
  • dysuria
  • nausea
  • deep vein thrombosis
  • diverticular perforation
  • duodenal ulcer perforation
  • haemoglobin decreased
1 - 6 months:
  • atherosclerosis
  • hypertension
  • ischaemic stroke
  • type 2 diabetes mellitus
  • erythema
  • dry skin
  • gait disturbance
  • hypokinesia
  • joint range of motion decreased
  • muscle contracture
6 - 12 months:
  • shortness of breath
  • pain
  • pain in extremity
  • oedema peripheral
  • deep vein thrombosis
  • pulmonary embolism
  • muscular weakness
  • abasia
  • burning sensation
  • deformity
1 - 2 years:
  • shortness of breath
  • atherosclerosis
  • hypertension
  • ischaemic stroke
  • type 2 diabetes mellitus
  • international normalised ratio increased
  • epistaxis
  • haematoma
  • haemoptysis
2 - 5 years:
  • acute myeloid leukaemia
  • cardiac failure
  • myelodysplastic syndrome
  • nephrogenic systemic fibrosis
  • basal cell carcinoma
  • bleeding time abnormal
  • blood pressure systolic increased
  • cerebrovascular disorder
  • fatigue
  • international normalised ratio increased
5 - 10 years:
  • confusional state
  • disorientation
  • fatigue
  • fever
  • lethargy
  • pupil fixed
  • sleepiness
  • acute respiratory distress syndrome
  • thrombocytopenia
not specified:
  • pain
  • anxiety
  • dyspnoea
  • anaemia
  • injury
  • osteonecrosis of jaw
  • nausea
  • fatigue
  • back pain
  • atrial fibrillation

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • osteonecrosis of jaw
  • injury
  • dyspnoea
  • nausea
  • anaemia
  • hypokalaemia
  • asthenia
  • back pain
male:
  • pain
  • anaemia
  • anxiety
  • oedema peripheral
  • dyspnoea
  • fatigue
  • international normalised ratio increased
  • atrial fibrillation
  • back pain
  • injury

Most common drug interactions by age *:

10-19:
  • alopecia
  • anaemia
  • ataxia
  • cellulitis
  • constipation
  • dysphagia
  • fatigue
  • gait disturbance
  • intervertebral disc degeneration
  • osteomyelitis
20-29:
  • pain
  • pain in extremity
  • deep vein thrombosis
  • pulmonary embolism
  • anxiety
  • injury
  • oedema peripheral
  • anhedonia
  • back pain
  • bone erosion
30-39:
  • nausea
  • pulmonary embolism
  • chest pain
  • pain
  • back pain
  • dyspnoea
  • sepsis
  • thrombocytopenia
  • anxiety
  • dizziness
40-49:
  • pain
  • dyspnoea
  • anxiety
  • pyrexia
  • nausea
  • injury
  • back pain
  • chest pain
  • compression fracture
  • osteonecrosis of jaw
50-59:
  • pain
  • anxiety
  • depression
  • osteonecrosis of jaw
  • anaemia
  • injury
  • cardiac failure congestive
  • coronary artery disease
  • abdominal pain
  • hypokalaemia
60+:
  • atrial fibrillation
  • anaemia
  • pain
  • anxiety
  • dyspnoea
  • international normalised ratio increased
  • asthenia
  • injury
  • fatigue
  • oedema peripheral

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Cipro (ciprofloxacin hydrochloride) is often used to treat urinary tract infection. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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