Review: taking Coumadin and Lunesta together


Summary

Drug interactions are reported among people who take Coumadin and Lunesta together. This review analyzes the effectiveness and drug interactions between Coumadin and Lunesta. It is created by eHealthMe based on reports of 989 people who take the same drugs from FDA and social media, and is updated regularly.

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Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 101,806 users)

Lunesta

Lunesta has active ingredients of eszopiclone. It is often used in insomnia. (latest outcomes from Lunesta 18,765 users)

On Sep, 21, 2016

989 people who take Coumadin, Lunesta are studied.


Number of reports submitted per year:

Coumadin and Lunesta drug interactions.

Drug effectiveness over time:

Coumadin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 100.0% - (2 of 2 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Lunesta:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 33.0% - (1 of 3 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Coumadin:
  • female: 80.0% - (4 of 5 people)
  • male: 50.0% - (1 of 2 people)
Lunesta:
  • female: 50.0% - (3 of 6 people)
  • male: 0.0% - (0 of 3 people)

Drug effectiveness by age:

Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 50.0% - (1 of 2 people)
  • 60+: 66.0% - (2 of 3 people)
Lunesta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 0.0% - (0 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • somnolence
  • blood pressure decreased
  • drug ineffective
  • dysphagia
  • general physical health deterioration
  • injection site haemorrhage
  • lower respiratory tract infection
  • urinary tract infection
  • subcutaneous haematoma
  • anticoagulation drug level above therapeutic
1 - 6 months:
  • drug effect decreased
  • international normalised ratio increased
  • diarrhoea
  • dizziness
  • dysgeusia
  • blood pressure systolic decreased
  • bronchitis
  • cardiac output decreased
  • depression
  • drug ineffective
6 - 12 months:
  • hypersensitivity pneumonitis
  • interstitial lung disease
  • dizziness
  • fall
  • drug ineffective
  • dyspnoea
  • hypovolaemia
  • laceration
  • syncope
  • crohn's disease
1 - 2 years:
  • hypersensitivity pneumonitis
  • interstitial lung disease
  • acute myeloid leukaemia
  • amnesia
  • angina pectoris
  • confusional state
  • drug ineffective
  • dysgeusia
  • initial insomnia
  • insomnia
2 - 5 years:
  • blood pressure increased
  • chest pain
  • diarrhoea
  • dysuria
  • eczema
  • eosinophilic pneumonia
  • eye pruritus
  • laryngeal oedema
  • neutropenic sepsis
  • parotid gland enlargement
5 - 10 years:
  • chest pain
  • neutropenic sepsis
10+ years:
  • cardiac failure
  • grand mal convulsion
  • hypoxic-ischaemic encephalopathy
  • migraine
  • pain
  • respiratory failure
  • unresponsive to stimuli
  • withdrawal syndrome
  • cardiac arrest
  • epistaxis
not specified:
  • dyspnoea
  • pain
  • nausea
  • fall
  • fatigue
  • weight decreased
  • insomnia
  • dizziness
  • arthralgia
  • chest pain

Most common drug interactions by gender *:

female:
  • dyspnoea
  • pain
  • somnolence
  • gastrooesophageal reflux disease
  • dysphagia
  • constipation
  • general physical health deterioration
  • nausea
  • international normalised ratio increased
  • urinary tract infection
male:
  • drug ineffective
  • dyspnoea
  • nausea
  • dizziness
  • atrial fibrillation
  • insomnia
  • fatigue
  • fall
  • pain
  • hypotension

Most common drug interactions by age *:

10-19:
  • optic ischaemic neuropathy
  • visual acuity reduced
20-29:
  • back pain
  • deep vein thrombosis
  • erythema
  • hypoaesthesia
  • iliac artery embolism
  • joint swelling
  • oedema peripheral
  • pain in extremity
  • sciatica
  • spider vein
30-39:
  • nausea
  • chest pain
  • renal failure
  • vomiting
  • atrial fibrillation
  • atrioventricular block complete
  • endocarditis
  • pain
  • dyspnoea
  • sepsis
40-49:
  • weight decreased
  • cholecystitis acute
  • dizziness
  • atrial fibrillation
  • mitral valve incompetence
  • fatigue
  • aortic valve calcification
  • cardiac failure
  • hypokalaemia
  • pyrexia
50-59:
  • dyspnoea
  • pain
  • nausea
  • pain in extremity
  • anxiety
  • neuropathy peripheral
  • paraesthesia
  • pyrexia
  • fall
  • hypoaesthesia
60+:
  • somnolence
  • drug ineffective
  • insomnia
  • dyspnoea
  • international normalised ratio increased
  • fall
  • gastrooesophageal reflux disease
  • nausea
  • fatigue
  • urinary tract infection

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Lunesta (eszopiclone) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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