Review: taking Coumadin and Melatonin together


Summary

Drug interactions are reported among people who take Coumadin and Melatonin together. This review analyzes the effectiveness and drug interactions between Coumadin and Melatonin. It is created by eHealthMe based on reports of 413 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 101,806 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 8,403 users)

On Sep, 16, 2016

413 people who take Coumadin, Melatonin are studied.


Number of reports submitted per year:

Coumadin and Melatonin drug interactions.

Drug effectiveness over time:

Coumadin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 100.0% - (2 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Melatonin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Coumadin:
  • female: 100.0% - (1 of 1 people)
  • male: 66.0% - (2 of 3 people)
Melatonin:
  • female: 50.0% - (1 of 2 people)
  • male: 0.0% - (0 of 3 people)

Drug effectiveness by age:

Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 100.0% - (3 of 3 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • abdominal discomfort
  • agitation
  • anxiety
  • cerebrovascular accident
  • cognitive deterioration
  • delusions, mixed
  • device related infection
  • dystonia
  • hallucination, visual
  • hypertension
1 - 6 months:
  • skin blushing/flushing
  • alopecia
  • asthenia
  • hypoglycaemia
  • vision blurred
6 - 12 months:
  • anaemia
  • diarrhoea
  • haematemesis
  • haemorrhage
  • impaired gastric emptying
1 - 2 years:
  • lower gastrointestinal haemorrhage
  • muscle spasms
  • septic shock
  • sputum culture positive
  • faeces discoloured
  • international normalised ratio increased
  • rectal haemorrhage
  • acute interstitial pneumonitis
  • device related infection
  • diffuse alveolar damage
2 - 5 years:
  • skin blushing/flushing
5 - 10 years:
  • fall
  • muscle spasms
  • traumatic intracranial haemorrhage
not specified:
  • pneumonia aspiration
  • somnolence
  • dyspnoea
  • pneumonia
  • gastrooesophageal reflux disease
  • coma
  • pain
  • urinary tract infection
  • asthenia
  • fatigue

Most common drug interactions by gender *:

female:
  • pneumonia aspiration
  • somnolence
  • coma
  • gastrooesophageal reflux disease
  • pneumonia
  • bronchitis
  • urinary tract infection
  • dyspnoea
  • pain
  • deep vein thrombosis
male:
  • asthenia
  • atrial fibrillation
  • fatigue
  • drug ineffective
  • dyspnoea
  • fall
  • pain
  • dizziness
  • nausea
  • confusional state

Most common drug interactions by age *:

0-1:
  • abdominal distension
  • malabsorption
  • vomiting
2-9:
  • chest discomfort
  • fatigue
  • pulmonary arterial hypertension
  • rhinovirus infection
  • streptococcal infection
  • streptococcus test positive
  • syncope
10-19:
  • conversion disorder
  • device expulsion
  • fatigue
  • menorrhagia
  • nausea
  • vaginal discharge
  • vulvovaginal mycotic infection
20-29:
  • cellulitis
  • pain
  • urinary tract infection
  • vomiting
  • weight decreased
  • respiratory failure
  • actinomyces test positive
  • acute psychosis
  • amnesia
  • asthenia
30-39:
  • headache
  • back pain
  • cardiac disorder
  • constipation
  • diarrhoea
  • discomfort
  • disease progression
  • dysgeusia
  • dyspnoea
  • emotional distress
40-49:
  • bronchitis
  • cystitis
  • cystitis haemorrhagic
  • hip arthroplasty
  • pneumonia
  • pneumonia aspiration
  • urinary bladder haemorrhage
  • bladder prolapse
  • intestinal prolapse
  • urinary tract infection
50-59:
  • arthralgia
  • pain
  • nausea
  • international normalised ratio increased
  • tremor
  • cellulitis
  • chest pain
  • diarrhoea
  • dyspnoea
  • joint injury
60+:
  • gastrooesophageal reflux disease
  • somnolence
  • pneumonia aspiration
  • coma
  • fall
  • fatigue
  • asthenia
  • diarrhoea
  • atrial fibrillation
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Coumadin and Melatonin?

Can you answer these questions?

More questions for: Coumadin, Melatonin

You may be interested in these reviews

More reviews for: Coumadin, Melatonin

On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.