Coumadin and Metformin drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Coumadin and Metformin together. This review analyzes the effectiveness and drug interactions between Coumadin and Metformin. It is created by eHealthMe based on reports of 9,190 people who take the same drugs from FDA, and is updated regularly.

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Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from Coumadin 103,655 users)

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 183,350 users)

On Jan, 23, 2017

9,190 people who take Coumadin, Metformin are studied.


Number of reports submitted per year:

Coumadin and Metformin drug interactions.

Most common drug interactions over time *:

< 1 month:
  • international normalised ratio increased
  • dyspnoea
  • blood creatine phosphokinase increased
  • muscular weakness
  • myositis
  • anaemia
  • diarrhoea
  • nausea
  • myocardial infarction
  • thrombocytopenia
1 - 6 months:
  • confusional state
  • cerebral infarction
  • sedation
  • pyrexia
  • headache
  • international normalised ratio increased
  • vomiting
  • fatigue
  • bradycardia
  • amnesia
6 - 12 months:
  • atrial fibrillation
  • renal failure acute
  • dyspnoea
  • metabolic acidosis
  • aortic valve sclerosis
  • atrial flutter
  • cough
  • diabetic retinopathy
  • dizziness
  • flushing
1 - 2 years:
  • lactic acidosis
  • renal failure
  • anaemia
  • pain
  • dyspnoea
  • deep vein thrombosis
  • hypoglycaemia
  • rectal haemorrhage
  • asthenia
  • atrial fibrillation
2 - 5 years:
  • international normalised ratio increased
  • anaemia
  • lactic acidosis
  • myocardial infarction
  • renal failure acute
  • cerebral haemorrhage
  • atrial fibrillation
  • diarrhoea
  • fall
  • dehydration
5 - 10 years:
  • cardiac failure congestive
  • anaemia
  • cerebrovascular accident
  • depression
  • dizziness
  • thrombocytopenia
  • chest pain
  • coronary artery disease
  • diabetes mellitus
  • fall
10+ years:
  • renal failure acute
  • bradycardia
  • mental status changes
  • anuria
  • cardiogenic shock
  • coagulopathy
  • coma
  • international normalised ratio increased
  • lactic acidosis
  • metabolic acidosis
not specified:
  • dyspnoea
  • nausea
  • atrial fibrillation
  • fatigue
  • international normalised ratio increased
  • pain
  • cardiac failure congestive
  • dizziness
  • asthenia
  • diarrhoea

Most common drug interactions by gender *:

female:
  • dyspnoea
  • nausea
  • international normalised ratio increased
  • pain
  • fatigue
  • atrial fibrillation
  • fall
  • asthenia
  • cardiac failure congestive
  • dizziness
male:
  • dyspnoea
  • atrial fibrillation
  • international normalised ratio increased
  • cardiac failure congestive
  • fatigue
  • dizziness
  • pain
  • nausea
  • asthenia
  • diarrhoea

Most common drug interactions by age *:

0-1:
  • muscular weakness
  • tremor
  • atrial fibrillation
  • cerebrovascular accident
  • neoplasm malignant
  • thrombophlebitis superficial
10-19:
  • deep vein thrombosis
  • pain
  • pain in extremity
  • pulmonary embolism
  • chest pain
  • activities of daily living impaired
  • cholelithiasis
  • dizziness
  • hypercoagulation
  • injury
20-29:
  • drug ineffective
  • liver injury
  • deep vein thrombosis
  • pain
  • pulmonary embolism
  • epilepsy
  • hypoglycaemia
  • injury
  • lip injury
  • pain in extremity
30-39:
  • pain
  • anxiety
  • deep vein thrombosis
  • malaise
  • pulmonary embolism
  • type 2 diabetes mellitus
  • urinary tract infection
  • sinus tachycardia
  • convulsion
  • dysphagia
40-49:
  • dyspnoea
  • nausea
  • fatigue
  • pain
  • diabetes mellitus
  • myocardial infarction
  • vomiting
  • headache
  • diarrhoea
  • anxiety
50-59:
  • nausea
  • dyspnoea
  • atrial fibrillation
  • cardiac failure congestive
  • myocardial infarction
  • oedema peripheral
  • fatigue
  • pain
  • diarrhoea
  • international normalised ratio increased
60+:
  • dyspnoea
  • international normalised ratio increased
  • atrial fibrillation
  • nausea
  • cardiac failure congestive
  • dizziness
  • fatigue
  • asthenia
  • fall
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Coumadin and Metformin?

Interactions between Coumadin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Metformin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

Can you answer these questions?

More questions for: Coumadin, Metformin

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