Review: taking Coumadin and Neurontin together


Summary

Drug interactions are reported among people who take Coumadin and Neurontin together. This review analyzes the effectiveness and drug interactions between Coumadin and Neurontin. It is created by eHealthMe based on reports of 8,609 people who take the same drugs from FDA and social media, and is updated regularly.

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Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 101,806 users)

Neurontin

Neurontin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Neurontin 76,477 users)

On Sep, 20, 2016

8,609 people who take Coumadin, Neurontin are studied.


Number of reports submitted per year:

Coumadin and Neurontin drug interactions.

Drug effectiveness over time:

Coumadin:
  • < 1 month: 25.0% - (1 of 4 people)
  • 1 - 6 months: 50.0% - (4 of 8 people)
  • 6 - 12 months: 46.0% - (6 of 13 people)
  • 1 - 2 years: 55.0% - (5 of 9 people)
  • 2 - 5 years: 59.0% - (13 of 22 people)
  • 5 - 10 years: 72.0% - (8 of 11 people)
  • 10+ years: 78.0% - (11 of 14 people)
  • not specified: 100.0% - (2 of 2 people)
Neurontin:
  • < 1 month: 0.0% - (0 of 10 people)
  • 1 - 6 months: 21.0% - (3 of 14 people)
  • 6 - 12 months: 22.0% - (2 of 9 people)
  • 1 - 2 years: 28.0% - (4 of 14 people)
  • 2 - 5 years: 38.0% - (7 of 18 people)
  • 5 - 10 years: 29.0% - (5 of 17 people)
  • 10+ years: 0.0% - (0 of 5 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Coumadin:
  • female: 60.0% - (27 of 45 people)
  • male: 60.0% - (23 of 38 people)
Neurontin:
  • female: 25.0% - (12 of 48 people)
  • male: 22.0% - (9 of 40 people)

Drug effectiveness by age:

Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 75.0% - (3 of 4 people)
  • 40-49: 61.0% - (11 of 18 people)
  • 50-59: 64.0% - (11 of 17 people)
  • 60+: 56.0% - (23 of 41 people)
Neurontin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 50.0% - (2 of 4 people)
  • 40-49: 26.0% - (5 of 19 people)
  • 50-59: 15.0% - (3 of 19 people)
  • 60+: 25.0% - (11 of 43 people)

Most common drug interactions over time *:

< 1 month:
  • fall
  • confusional state
  • tremor
  • hallucination, visual
  • international normalised ratio increased
  • somnolence
  • thrombocytopenia
  • pneumonia
  • hallucination
  • deep vein thrombosis
1 - 6 months:
  • dyspnoea
  • oedema peripheral
  • cerebral infarction
  • chest pain
  • headache
  • cellulitis
  • anaemia
  • pain
  • international normalised ratio increased
  • bradycardia
6 - 12 months:
  • dyspnoea
  • atrial fibrillation
  • dizziness
  • anxiety
  • aortic valve sclerosis
  • atrial flutter
  • cough
  • diabetic retinopathy
  • flushing
  • myalgia
1 - 2 years:
  • nephrogenic systemic fibrosis
  • anxiety
  • pain in extremity
  • gangrene
  • pleural effusion
  • pneumonia
  • pulmonary hypertension
  • cellulitis
  • cough
  • impaired healing
2 - 5 years:
  • pain
  • anxiety
  • drug ineffective
  • atrial fibrillation
  • hypertension
  • peripheral sensory neuropathy
  • amnesia
  • pneumonia
  • depression
  • nephrogenic systemic fibrosis
5 - 10 years:
  • gastrointestinal haemorrhage
  • anaemia
  • cerebrovascular accident
  • depression
  • fall
  • international normalised ratio increased
  • myocardial infarction
  • cardiac disorder
  • dyspnoea
  • fatigue - chronic
10+ years:
  • hives
  • itching
  • rash generalised
  • renal impairment
  • urticaria
  • cerebral haemorrhage
  • subdural haematoma
  • cardiac failure
  • coagulation time prolonged
  • dementia
not specified:
  • pain
  • dyspnoea
  • anxiety
  • fatigue
  • nausea
  • fall
  • anaemia
  • oedema peripheral
  • pneumonia
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • dyspnoea
  • fall
  • fatigue
  • pain in extremity
  • oedema peripheral
  • pneumonia
  • back pain
male:
  • pain
  • dyspnoea
  • anaemia
  • anxiety
  • pneumonia
  • oedema peripheral
  • fatigue
  • fall
  • asthenia
  • injury

Most common drug interactions by age *:

0-1:
  • orthostatic hypotension
2-9:
  • abdominal pain
  • anaemia
  • abasia
  • arthralgia
  • bursitis
  • femur fracture
  • pain in extremity
  • stress fracture
  • actinic keratosis
  • appendicitis
10-19:
  • nausea
  • drug ineffective
  • anaemia
  • arteriosclerosis
  • constipation
  • dysphagia
  • dyspnoea
  • fatigue
  • gastrooesophageal reflux disease
  • headache
20-29:
  • dyspnoea
  • pain
  • headache
  • vomiting
  • nausea
  • oedema peripheral
  • pain in extremity
  • musculoskeletal pain
  • pneumonia
  • deep vein thrombosis
30-39:
  • anxiety
  • pain
  • fatigue
  • depression
  • pain in extremity
  • nausea
  • pyrexia
  • asthenia
  • headache
  • hypoaesthesia
40-49:
  • pain
  • anxiety
  • pain in extremity
  • nausea
  • dyspnoea
  • neuropathy peripheral
  • oedema peripheral
  • injury
  • osteonecrosis of jaw
  • abdominal pain
50-59:
  • pain
  • anxiety
  • fatigue
  • osteonecrosis of jaw
  • anaemia
  • dyspnoea
  • pneumonia
  • oedema peripheral
  • depression
  • nausea
60+:
  • pain
  • fall
  • dyspnoea
  • pneumonia
  • anaemia
  • fatigue
  • anxiety
  • oedema peripheral
  • nausea
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Neurontin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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