Coumadin and Phenytoin drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Coumadin and Phenytoin together. This review analyzes the effectiveness and drug interactions between Coumadin and Phenytoin. It is created by eHealthMe based on reports of 1,817 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Coumadin and Phenytoin, find out what symptoms you could have in 1 year or longer.

You are not alone!

Join a support group for people who take Coumadin and Phenytoin

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA since 1977. Our tools are simple to use, anonymous and free. Start now >>>

Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in blood clots. (latest outcomes from Coumadin 103,655 users)

Phenytoin

Phenytoin has active ingredients of phenytoin. It is often used in epilepsy. (latest outcomes from Phenytoin 12,320 users)

On Feb, 14, 2017

1,817 people who take Coumadin, Phenytoin are studied.


Number of reports submitted per year:

Coumadin and Phenytoin drug interactions.

Most common drug interactions over time *:

< 1 month:
  • international normalised ratio increased
  • alanine aminotransferase increased
  • stevens-johnson syndrome
  • transaminases increased
  • convulsion
  • hereditary angioedema
  • pancreatitis
  • urinary tract infection
  • pancytopenia
  • pyrexia
1 - 6 months:
  • cardiomegaly
  • coma hepatic
  • hepatic failure
  • hepatorenal syndrome
  • hyperthyroidism
  • blindness unilateral
  • hypotension
  • international normalised ratio increased
  • stevens-johnson syndrome
  • delirium
6 - 12 months:
  • myelodysplastic syndrome
  • brain herniation
  • cholecystitis acute
  • cholelithiasis
  • drug level increased
  • fall
  • speech disorder
  • subdural haematoma
  • abdominal wall haematoma
  • blood creatinine increased
1 - 2 years:
  • fall
  • syncope
  • arthropathy
  • blood viscosity increased
  • deep vein thrombosis
  • dizziness (excl vertigo)
  • drug level increased
  • insomnia
  • laceration
  • lethargy
2 - 5 years:
  • fall
  • aphasia
  • cerebral artery embolism
  • cerebral haemorrhage
  • confusional state
  • convulsion
  • haemorrhagic stroke
  • headache
  • insomnia
  • akathisia
5 - 10 years:
  • international normalised ratio increased
  • anticonvulsant drug level decreased
  • convulsion
  • abdominal distension
  • abdominal pain lower
  • aphasia
  • bladder disorder
  • cardiac disorder
  • cardio-respiratory arrest
  • chest pain
10+ years:
  • dizziness
  • arthritis
  • cartilage injury
  • deafness unilateral
  • drug ineffective
  • dysuria
  • fatigue
  • foot fracture
  • herpes zoster
  • international normalised ratio increased
not specified:
  • convulsion
  • pain
  • international normalised ratio increased
  • fall
  • dyspnoea
  • asthenia
  • headache
  • fatigue
  • pneumonia
  • anxiety

Most common drug interactions by gender *:

female:
  • pain
  • headache
  • asthenia
  • convulsion
  • depression
  • fall
  • dyspnoea
  • pain in extremity
  • international normalised ratio increased
  • anxiety
male:
  • convulsion
  • international normalised ratio increased
  • fall
  • pain
  • dyspnoea
  • oedema peripheral
  • deep vein thrombosis
  • renal failure
  • fatigue
  • pneumonia

Most common drug interactions by age *:

0-1:
  • sedation
  • weakness
2-9:
  • mucosal haemorrhage
  • thrombocytopenia
  • anxiety
  • death
  • depression
  • fear
  • injury
  • multi-organ failure
  • pain
  • renal failure
10-19:
  • convulsion
  • international normalised ratio increased
  • family stress
  • renal tubular disorder
  • stevens-johnson syndrome
  • tardive dyskinesia
  • alopecia
  • arrhythmia
  • atrial fibrillation
  • bradycardia
20-29:
  • pain
  • nephrogenic systemic fibrosis
  • mobility decreased
  • peroneal nerve palsy
  • skin depigmentation
  • skin tightness
  • oedema
  • dry skin
  • headache
  • skin hyperpigmentation
30-39:
  • pain
  • oedema peripheral
  • nephrogenic systemic fibrosis
  • joint contracture
  • joint range of motion decreased
  • skin hypertrophy
  • skin tightness
  • pruritus
  • anxiety
  • drug ineffective
40-49:
  • deep vein thrombosis
  • urinary tract infection
  • anaemia
  • confusional state
  • oedema peripheral
  • convulsion
  • international normalised ratio increased
  • pancreatitis
  • hereditary angioedema
  • cytokine storm
50-59:
  • arthralgia
  • pain
  • international normalised ratio increased
  • anxiety
  • convulsion
  • pain in extremity
  • fall
  • oedema peripheral
  • back pain
  • bronchitis
60+:
  • convulsion
  • international normalised ratio increased
  • fall
  • pain
  • asthenia
  • depression
  • dyspnoea
  • headache
  • pneumonia
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Coumadin and Phenytoin?

Interactions between Coumadin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Phenytoin and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Phenytoin (phenytoin) is often used to treat convulsion. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

Can you answer these questions?

More questions for: Coumadin, Phenytoin

You may be interested in these reviews

More reviews for: Coumadin, Phenytoin