Review: taking Coumadin and Sudafed together


Summary

Drug interactions are reported among people who take Coumadin and Sudafed together. This review analyzes the effectiveness and drug interactions between Coumadin and Sudafed. It is created by eHealthMe based on reports of 187 people who take the same drugs from FDA and social media, and is updated regularly.

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Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 101,806 users)

Sudafed

Sudafed has active ingredients of pseudoephedrine hydrochloride. It is often used in sinus congestion. (latest outcomes from Sudafed 7,064 users)

On Sep, 18, 2016

187 people who take Coumadin, Sudafed are studied.


Number of reports submitted per year:

Coumadin and Sudafed drug interactions.

Drug effectiveness over time:

Coumadin:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 50.0% - (2 of 4 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Sudafed:
  • < 1 month: 50.0% - (4 of 8 people)
  • 1 - 6 months: 100.0% - (1 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 33.0% - (1 of 3 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Coumadin:
  • female: 71.0% - (5 of 7 people)
  • male: 50.0% - (3 of 6 people)
Sudafed:
  • female: 62.0% - (5 of 8 people)
  • male: 28.0% - (2 of 7 people)

Drug effectiveness by age:

Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 60.0% - (3 of 5 people)
  • 50-59: 50.0% - (1 of 2 people)
  • 60+: 66.0% - (2 of 3 people)
Sudafed:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 50.0% - (1 of 2 people)
  • 40-49: 66.0% - (4 of 6 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 0.0% - (0 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • cerebrovascular accident
  • insomnia
  • accidental overdose
  • anxiety
  • arthralgia
  • bladder disorder
  • catheter related infection
  • cystitis
  • decreased appetite
  • delusional perception
1 - 6 months:
  • headache
  • abscess intestinal
  • atelectasis
  • cardiolipin antibody positive
  • cervical cyst
  • cholecystitis chronic
  • cholelithiasis
  • coagulation factor ix level decreased
  • coagulopathy
  • constipation
6 - 12 months:
  • arthralgia
  • decreased appetite
  • dizziness aggravated
  • dry skin
  • erythema
  • fatigue
  • headache
  • hypokalaemia
  • hyponatraemia
  • oral discomfort
2 - 5 years:
  • international normalised ratio increased
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • headaches
  • non-cardiac chest pain
  • weight gain - unintentional
10+ years:
  • anaemia
  • cardiac failure congestive
  • concomitant disease progression
  • dizziness
  • dyspnoea
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fluid retention
  • haematuria
  • headaches
  • herpes zoster
not specified:
  • sinusitis
  • oedema peripheral
  • pain
  • back pain
  • abscess
  • depression
  • computerised tomogram abnormal
  • fistula
  • inflammation
  • tooth disorder

Most common drug interactions by gender *:

female:
  • sinusitis
  • pain
  • back pain
  • depression
  • abscess
  • computerised tomogram abnormal
  • fistula
  • inflammation
  • tooth disorder
  • arthralgia
male:
  • oedema peripheral
  • deep vein thrombosis
  • dyspnoea
  • renal failure
  • hyperglycaemia
  • respiratory failure
  • atrial fibrillation
  • cardiac failure congestive
  • chest pain
  • international normalised ratio increased

Most common drug interactions by age *:

10-19:
  • arthralgia
  • decreased appetite
  • dry skin
  • erythema
  • fatigue
  • headache
  • hypokalaemia
  • oral discomfort
  • pain of skin
  • paraesthesia oral
20-29:
  • abdominal abscess
  • adrenal insufficiency
  • atrial fibrillation
  • cardiac tamponade
  • delusion
  • depression
  • enterococcal infection
  • escherichia infection
  • fall
  • fungal infection
30-39:
  • urinary tract infection
  • vomiting
  • thrombosis
  • insomnia
  • intracardiac thrombus
  • nasopharyngitis
  • nausea
  • pulmonary thrombosis
  • sinusitis
  • constipation
40-49:
  • abdominal pain
  • abdominal pain upper
  • abscess
  • back pain
  • basal cell carcinoma
  • bone disorder
  • carotid artery stenosis
  • cataract
  • cholelithiasis
  • computerised tomogram abnormal
50-59:
  • sinusitis
  • cough
  • insomnia
  • anorexia
  • back pain
  • dysgeusia
  • flank pain
  • osteonecrosis
  • pyrexia
  • sinus congestion
60+:
  • asthenia
  • fatigue
  • oedema peripheral
  • depression
  • neck pain
  • pain
  • urinary tract infection
  • anaemia
  • anxiety
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Sudafed (pseudoephedrine hydrochloride) is often used to treat sinus congestion. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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