Review: taking Coumadin and Vesicare together


Summary

Drug interactions are reported among people who take Coumadin and Vesicare together. This review analyzes the effectiveness and drug interactions between Coumadin and Vesicare. It is created by eHealthMe based on reports of 454 people who take the same drugs from FDA and social media, and is updated regularly.

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Coumadin

Coumadin has active ingredients of warfarin sodium. It is often used in atrial fibrillation/flutter. (latest outcomes from Coumadin 80,735 users)

Vesicare

Vesicare has active ingredients of solifenacin succinate. It is often used in hypertonic bladder. (latest outcomes from Vesicare 10,561 users)

On Aug, 22, 2016

454 people who take Coumadin, Vesicare are studied.


Number of reports submitted per year:

Coumadin and Vesicare drug interactions.

Drug effectiveness over time:

Coumadin:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 100.0% - (1 of 1 people)
Vesicare:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Coumadin:
  • female: 50.0% - (2 of 4 people)
  • male: 100.0% - (4 of 4 people)
Vesicare:
  • female: 50.0% - (2 of 4 people)
  • male: 50.0% - (2 of 4 people)

Drug effectiveness by age:

Coumadin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 85.0% - (6 of 7 people)
Vesicare:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 0 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 57.0% - (4 of 7 people)

Most common drug interactions over time *:

< 1 month:
  • urinary retention
  • insomnia
  • drug ineffective
  • pruritus generalised
  • urticaria
  • acute myocardial infarction
  • angina unstable
  • anxiety
  • ascites
  • asthma
1 - 6 months:
  • dry mouth
  • atrial fibrillation
  • decubitus ulcer
  • dyspnoea
  • interstitial lung disease
  • purpura
  • pyrexia
  • vasculitis
  • arthralgia
  • arthritis
6 - 12 months:
  • cerebral infarction
  • confusional state
  • death
  • dizziness
  • dysphagia
  • fatigue
  • somnolence
1 - 2 years:
  • activities of daily living impaired
  • aortic valve disease
  • convulsion
  • coronary artery occlusion
  • death
  • dementia
  • dementia alzheimer's type
  • haematuria
  • haemorrhage
  • incontinence
2 - 5 years:
  • atrial fibrillation
  • dry mouth
  • haemorrhage
  • post procedural haemorrhage
  • postoperative thrombosis
  • stevens-johnson syndrome
  • thrombosis
5 - 10 years:
  • bladder pain
  • lung disorder
  • cardiac disorder
  • cardiovascular insufficiency
  • death
  • drug ineffective
  • dry eye
  • eye pain
  • headache
  • heart valve incompetence
10+ years:
  • facial edema
not specified:
  • pain
  • dyspnoea
  • fall
  • headache
  • pyrexia
  • urinary tract infection
  • pneumonia
  • diarrhoea
  • chest pain
  • chronic obstructive pulmonary disease

Most common drug interactions by gender *:

female:
  • urinary tract infection
  • fall
  • pain
  • atrial fibrillation
  • international normalised ratio increased
  • depression
  • dyspnoea
  • drug ineffective
  • fatigue
  • anaemia
male:
  • dyspnoea
  • neutropenia
  • pyrexia
  • chronic obstructive pulmonary disease
  • headache
  • hypotension
  • diarrhoea
  • erectile dysfunction
  • anxiety
  • chest pain

Most common drug interactions by age *:

20-29:
  • anxiety
  • bipolar disorder
  • drug ineffective
  • insomnia
  • depression
  • hypomania
  • international normalised ratio increased
  • mood swings
30-39:
  • fall
  • ligament sprain
  • nausea
  • osteopenia
  • pneumonia
  • arthralgia
  • abscess
  • activities of daily living impaired
  • agitation
  • anhedonia
40-49:
  • constipation
  • deep vein thrombosis
  • haemoglobin decreased
  • neutropenia
  • pain in extremity
  • thrombocytopenia
  • urinary tract infection
  • multiple myeloma
  • international normalised ratio increased
  • candidiasis
50-59:
  • pyrexia
  • dyspnoea
  • lymphadenopathy
  • back pain
  • bone marrow failure
  • diverticulum
  • neutropenia
  • pancytopenia
  • primary sequestrum
  • tooth abscess
60+:
  • atrial fibrillation
  • fall
  • urinary tract infection
  • dizziness
  • pain
  • international normalised ratio increased
  • dyspnoea
  • cardiac failure congestive
  • anaemia
  • multiple injuries

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Coumadin (warfarin sodium) is often used to treat atrial fibrillation/flutter. Vesicare (solifenacin succinate) is often used to treat hypertonic bladder. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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