Review: taking Crestor and Cymbalta together


Summary

Drug interactions are reported among people who take Crestor and Cymbalta together. This review analyzes the effectiveness and drug interactions between Crestor and Cymbalta. It is created by eHealthMe based on reports of 2,271 people who take the same drugs from FDA and social media, and is updated regularly.

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Crestor

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Crestor 90,212 users)

Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 89,411 users)

On Sep, 18, 2016

2,271 people who take Crestor, Cymbalta are studied.


Number of reports submitted per year:

Crestor and Cymbalta drug interactions.

Drug effectiveness over time:

Crestor:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 57.0% - (4 of 7 people)
  • 6 - 12 months: 43.0% - (7 of 16 people)
  • 1 - 2 years: 57.0% - (8 of 14 people)
  • 2 - 5 years: 51.0% - (18 of 35 people)
  • 5 - 10 years: 91.0% - (11 of 12 people)
  • 10+ years: 80.0% - (4 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Cymbalta:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 17.0% - (3 of 17 people)
  • 6 - 12 months: 22.0% - (2 of 9 people)
  • 1 - 2 years: 10.0% - (2 of 20 people)
  • 2 - 5 years: 46.0% - (15 of 32 people)
  • 5 - 10 years: 53.0% - (7 of 13 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Crestor:
  • female: 56.0% - (37 of 65 people)
  • male: 60.0% - (15 of 25 people)
Cymbalta:
  • female: 35.0% - (25 of 70 people)
  • male: 25.0% - (7 of 27 people)

Drug effectiveness by age:

Crestor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 75.0% - (3 of 4 people)
  • 40-49: 53.0% - (8 of 15 people)
  • 50-59: 51.0% - (23 of 45 people)
  • 60+: 69.0% - (18 of 26 people)
Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 25.0% - (1 of 4 people)
  • 40-49: 29.0% - (5 of 17 people)
  • 50-59: 30.0% - (15 of 50 people)
  • 60+: 44.0% - (11 of 25 people)

Most common drug interactions over time *:

< 1 month:
  • insomnia
  • dizziness
  • constipation
  • tremor
  • depression
  • nausea
  • delirium
  • fibromyalgia
  • agitation
  • chest pain
1 - 6 months:
  • insomnia
  • constipation
  • nasal congestion
  • acne cystic
  • bad breath
  • chronic fatigue syndrome
  • chronic sinusitis
  • meniere's disease aggravated
  • overactive bladder
  • dizziness
6 - 12 months:
  • blood creatine phosphokinase increased
  • lichen planus
  • flushing
  • musculoskeletal chest pain
  • pulmonary hypertension
  • arthralgia
  • burning feet syndrome
  • cerebral infarction
  • dizziness
  • dry mouth
1 - 2 years:
  • fatigue
  • depression
  • insomnia
  • anxiety
  • disturbance in attention
  • mental status changes
  • somnolence
  • tremor
  • confusional state
  • delirium
2 - 5 years:
  • heat intolerance
  • constipation aggravated
  • insomnia
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fatigue
  • memory impairment
  • myocardial infarction
  • dry mouth
  • feeling abnormal
  • crying
5 - 10 years:
  • chronic depression
  • drooling
  • incontinence
  • lack of strength, muscle weakness, weakness
  • muscle aches
  • muscular weakness
  • musculoskeletal stiffness
  • myalgia
  • insomnia
  • pulmonary hypertension
10+ years:
  • chronic depression
  • drooling
  • fatigue
  • heart fibrillation
  • heart rate increased
  • incontinence
  • joint pain
  • lack of strength, muscle weakness, weakness
  • carpal tunnel syndrome
  • depression
not specified:
  • nausea
  • pain
  • drug ineffective
  • fatigue
  • dizziness
  • insomnia
  • pain in extremity
  • headache
  • anxiety
  • depression

Most common drug interactions by gender *:

female:
  • nausea
  • dizziness
  • pain
  • insomnia
  • fatigue
  • drug ineffective
  • pain in extremity
  • fall
  • anxiety
  • headache
male:
  • drug ineffective
  • depression
  • fatigue
  • anxiety
  • insomnia
  • arthralgia
  • dyspnoea
  • nausea
  • headache
  • somnolence

Most common drug interactions by age *:

0-1:
  • anomaly of external ear congenital
  • polydactyly
  • premature baby
  • blood cholesterol increased
  • blood creatine phosphokinase increased
  • gallbladder operation
  • musculoskeletal disorder
  • musculoskeletal pain
  • myoglobin blood increased
  • pain in extremity
10-19:
  • ear infection
  • nausea
  • abdominal pain upper
  • blood cholesterol increased
  • drug ineffective
  • gastrooesophageal reflux disease
  • pharyngitis
  • convulsion
  • depression
  • arthropathy
20-29:
  • headache
  • injury
  • pain
  • fatigue
  • amnesia
  • asthma
  • cerebrovascular accident
  • concussion
  • confusional state
  • critical illness polyneuropathy
30-39:
  • weight increased
  • renal failure
  • renal failure acute
  • anxiety
  • drug withdrawal syndrome
  • dyspnoea
  • depression
  • chest pain
  • diabetes mellitus
  • palpitations
40-49:
  • insomnia
  • dizziness
  • constipation
  • migraine
  • nasal congestion
  • chronic fatigue syndrome
  • acne cystic
  • bad breath
  • chronic sinusitis
  • meniere's disease aggravated
50-59:
  • drug ineffective
  • nausea
  • pain
  • fatigue
  • insomnia
  • arthralgia
  • weight decreased
  • pain in extremity
  • depression
  • myocardial infarction
60+:
  • nausea
  • fall
  • dizziness
  • drug ineffective
  • pain
  • malaise
  • fatigue
  • anxiety
  • diarrhoea
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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