Review: taking Crestor and Cymbalta together


Summary

Drug interactions are reported among people who take Crestor and Cymbalta together. This review analyzes the effectiveness and drug interactions between Crestor and Cymbalta. It is created by eHealthMe based on reports of 1,588 people who take the same drugs from FDA and social media, and is updated regularly.

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Crestor

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Crestor 72,220 users)

Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 58,912 users)

On Aug, 26, 2016

1,588 people who take Crestor, Cymbalta are studied.


Number of reports submitted per year:

Crestor and Cymbalta drug interactions.

Drug effectiveness over time:

Crestor:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 57.0% - (4 of 7 people)
  • 6 - 12 months: 43.0% - (7 of 16 people)
  • 1 - 2 years: 57.0% - (8 of 14 people)
  • 2 - 5 years: 51.0% - (18 of 35 people)
  • 5 - 10 years: 91.0% - (11 of 12 people)
  • 10+ years: 80.0% - (4 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Cymbalta:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 17.0% - (3 of 17 people)
  • 6 - 12 months: 22.0% - (2 of 9 people)
  • 1 - 2 years: 10.0% - (2 of 19 people)
  • 2 - 5 years: 45.0% - (15 of 33 people)
  • 5 - 10 years: 53.0% - (7 of 13 people)
  • 10+ years: 50.0% - (2 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Crestor:
  • female: 56.0% - (37 of 65 people)
  • male: 60.0% - (15 of 25 people)
Cymbalta:
  • female: 35.0% - (25 of 70 people)
  • male: 25.0% - (7 of 27 people)

Drug effectiveness by age:

Crestor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 75.0% - (3 of 4 people)
  • 40-49: 53.0% - (8 of 15 people)
  • 50-59: 51.0% - (23 of 45 people)
  • 60+: 69.0% - (18 of 26 people)
Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 25.0% - (1 of 4 people)
  • 40-49: 29.0% - (5 of 17 people)
  • 50-59: 30.0% - (15 of 50 people)
  • 60+: 44.0% - (11 of 25 people)

Most common drug interactions over time *:

< 1 month:
  • insomnia
  • tremor
  • constipation
  • delirium
  • fibromyalgia
  • irritability
  • acne cystic
  • agitation
  • appetite - decreased
  • bad breath
1 - 6 months:
  • insomnia
  • constipation
  • nasal congestion
  • acne cystic
  • bad breath
  • chronic fatigue syndrome
  • chronic sinusitis
  • meniere's disease aggravated
  • overactive bladder
  • dizziness
6 - 12 months:
  • blood creatine phosphokinase increased
  • lichen planus
  • flushing
  • pulmonary hypertension
  • burning feet syndrome
  • dizziness
  • dry mouth
  • erectile dysfunction
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • heat cramps
1 - 2 years:
  • fatigue
  • depression
  • insomnia
  • anxiety
  • disturbance in attention
  • mental status changes
  • somnolence
  • tremor
  • confusional state
  • delirium
2 - 5 years:
  • heat intolerance
  • constipation aggravated
  • insomnia
  • exhaustion, fatigue, lethargy, tiredness, weariness
  • fatigue
  • memory impairment
  • dry mouth
  • crying
  • feeling abnormal
  • groin pain
5 - 10 years:
  • chronic depression
  • drooling
  • incontinence
  • lack of strength, muscle weakness, weakness
  • muscle aches
  • pulmonary hypertension
  • syncope
  • diarrhea
  • diarrhoea
  • dizziness
10+ years:
  • chronic depression
  • drooling
  • fatigue
  • heart fibrillation
  • heart rate increased
  • incontinence
  • joint pain
  • lack of strength, muscle weakness, weakness
  • carpal tunnel syndrome
  • depression
not specified:
  • pain
  • nausea
  • dizziness
  • fatigue
  • headache
  • pain in extremity
  • dyspnoea
  • fall
  • depression
  • insomnia

Most common drug interactions by gender *:

female:
  • dizziness
  • pain
  • nausea
  • insomnia
  • fall
  • constipation
  • fatigue
  • anxiety
  • diarrhoea
  • pain in extremity
male:
  • drug ineffective
  • dyspnoea
  • arthralgia
  • insomnia
  • fatigue
  • anxiety
  • headache
  • depression
  • pain
  • blood glucose increased

Most common drug interactions by age *:

0-1:
  • anomaly of external ear congenital
  • polydactyly
  • premature baby
  • blood cholesterol increased
  • blood creatine phosphokinase increased
  • gallbladder operation
  • musculoskeletal disorder
  • musculoskeletal pain
  • myoglobin blood increased
  • pain in extremity
10-19:
  • ear infection
  • nausea
  • convulsion
  • depression
  • abdominal pain upper
  • asthenia
  • balance disorder
  • blood cholesterol increased
  • confusional state
  • decreased interest
20-29:
  • abdominal pain
  • abdominal pain upper
  • anaemia
  • diarrhoea
  • fatigue
  • headache
  • cardiac disorder
  • chest pain
  • diabetes mellitus
  • mitral valve incompetence
30-39:
  • renal failure
  • renal failure acute
  • weight increased
  • diabetes mellitus
  • cardiac disorder
  • cholelithiasis
  • depression
  • intervertebral disc protrusion
  • neuropathy peripheral
  • type 2 diabetes mellitus
40-49:
  • dizziness
  • constipation
  • insomnia
  • nasal congestion
  • acne cystic
  • bad breath
  • chronic fatigue syndrome
  • chronic sinusitis
  • meniere's disease aggravated
  • overactive bladder
50-59:
  • nausea
  • drug ineffective
  • fatigue
  • insomnia
  • arthralgia
  • pain
  • weight decreased
  • diarrhoea
  • headache
  • dizziness
60+:
  • fall
  • nausea
  • pain
  • dizziness
  • asthenia
  • headache
  • diarrhoea
  • anxiety
  • dyspnoea
  • malaise

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Cymbalta (duloxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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