Review: taking Crestor and Lyrica together


Summary

Drug interactions are reported among people who take Crestor and Lyrica together. This review analyzes the effectiveness and drug interactions between Crestor and Lyrica. It is created by eHealthMe based on reports of 1,292 people who take the same drugs from FDA and social media, and is updated regularly.

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Crestor

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Crestor 57,941 users)

Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 64,307 users)

On Jul, 20, 2016

1,292 people who take Crestor, Lyrica are studied.


Number of reports submitted per year:

Crestor and Lyrica drug interactions.

Drug effectiveness over time:

Crestor:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 85.0% - (6 of 7 people)
  • 2 - 5 years: 45.0% - (5 of 11 people)
  • 5 - 10 years: 58.0% - (10 of 17 people)
  • 10+ years: 100.0% - (3 of 3 people)
  • not specified: 0.0% - (0 of 0 people)
Lyrica:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 27.0% - (3 of 11 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 33.0% - (3 of 9 people)
  • 2 - 5 years: 63.0% - (7 of 11 people)
  • 5 - 10 years: 83.0% - (5 of 6 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Crestor:
  • female: 53.0% - (14 of 26 people)
  • male: 52.0% - (10 of 19 people)
Lyrica:
  • female: 38.0% - (10 of 26 people)
  • male: 58.0% - (10 of 17 people)

Drug effectiveness by age:

Crestor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 46.0% - (6 of 13 people)
  • 60+: 66.0% - (14 of 21 people)
Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 71.0% - (5 of 7 people)
  • 50-59: 64.0% - (9 of 14 people)
  • 60+: 26.0% - (5 of 19 people)

Most common drug interactions over time *:

< 1 month:
  • oedema peripheral
  • drug ineffective
  • weight increased
  • insomnia
  • agitation
  • blood pressure increased
  • palpitations
  • arrhythmia
  • heart rate increased
  • localised oedema
1 - 6 months:
  • dizziness
  • weight increased
  • dyspnoea
  • drug ineffective
  • headache
  • pain
  • renal failure acute
  • withdrawal syndrome
  • amnesia
  • pain in extremity
6 - 12 months:
  • oedema peripheral
  • asthenia
  • cystitis
  • enterocolitis infectious
  • erythema
  • gastric disorder
  • abdominal pain upper
  • confusional state
  • depressed level of consciousness
  • depression aggravated
1 - 2 years:
  • hepatitis cholestatic
  • blood creatine phosphokinase increased
  • drug ineffective
  • headache
  • myalgia
  • renal failure acute
  • somnolence
  • arthralgia
  • asthenia
  • bone loss
2 - 5 years:
  • nausea
  • vomiting
  • dizziness
  • headache
  • hypertensive crisis
  • pulmonary embolism
  • renal failure acute
  • abdominal pain upper
  • disability
  • dry mouth
5 - 10 years:
  • chest pain
  • edema - peripheral, peripheral edema
  • hyperhidrosis
  • muscle cramps
  • syncope vasovagal
  • abdominal pain upper
  • anger
  • anorgasmia
  • bipolar disorder
  • blood pressure increased
not specified:
  • pain
  • weight increased
  • dyspnoea
  • drug ineffective
  • asthenia
  • dizziness
  • renal failure acute
  • nausea
  • somnolence
  • headache

Most common drug interactions by gender *:

female:
  • pain
  • drug ineffective
  • weight increased
  • asthenia
  • oedema peripheral
  • dyspnoea
  • dizziness
  • somnolence
  • insomnia
  • headache
male:
  • renal failure acute
  • dyspnoea
  • dizziness
  • malaise
  • weight increased
  • hypertension
  • hypoaesthesia
  • asthenia
  • drug ineffective
  • pneumonia

Most common drug interactions by age *:

0-1:
  • blood urine present
  • dyspnoea
  • gout
  • iron deficiency anaemia
  • metabolic disorder
  • myopathy
  • renal failure acute
  • rhabdomyolysis
20-29:
  • infusion related reaction
  • back pain
  • diabetes mellitus inadequate control
  • diabetic ketoacidosis
  • diabetic neuropathy
  • disease progression
  • hypotension
  • intervertebral disc protrusion
  • migraine
  • pruritus
30-39:
  • abdominal pain upper
  • arthropathy
  • chest pain
  • cholecystitis chronic
  • cholelithiasis
  • coronary artery occlusion
  • dislocation of vertebra
  • facial bones fracture
  • gallbladder cholesterolosis
  • hypercholesterolaemia
40-49:
  • weight increased
  • arthralgia
  • dyspnoea
  • diarrhoea
  • somnolence
  • dizziness
  • nausea
  • headache
  • withdrawal syndrome
  • gait disturbance
50-59:
  • renal failure acute
  • pain
  • malaise
  • drug ineffective
  • gastrointestinal disorder
  • anxiety
  • pain in extremity
  • weight increased
  • nausea
  • dyspnoea
60+:
  • weight increased
  • pain
  • drug ineffective
  • asthenia
  • dyspnoea
  • dizziness
  • oedema peripheral
  • insomnia
  • diarrhoea
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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