Review: taking Crestor and Lyrica together


Summary

Drug interactions are reported among people who take Crestor and Lyrica together. This review analyzes the effectiveness and drug interactions between Crestor and Lyrica. It is created by eHealthMe based on reports of 2,634 people who take the same drugs from FDA and social media, and is updated regularly.

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Crestor

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Crestor 90,212 users)

Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 121,583 users)

On Sep, 17, 2016

2,634 people who take Crestor, Lyrica are studied.


Number of reports submitted per year:

Crestor and Lyrica drug interactions.

Drug effectiveness over time:

Crestor:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 85.0% - (6 of 7 people)
  • 2 - 5 years: 50.0% - (5 of 10 people)
  • 5 - 10 years: 56.0% - (9 of 16 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Lyrica:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 30.0% - (3 of 10 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 37.0% - (3 of 8 people)
  • 2 - 5 years: 63.0% - (7 of 11 people)
  • 5 - 10 years: 80.0% - (4 of 5 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Crestor:
  • female: 56.0% - (14 of 25 people)
  • male: 47.0% - (8 of 17 people)
Lyrica:
  • female: 40.0% - (10 of 25 people)
  • male: 60.0% - (9 of 15 people)

Drug effectiveness by age:

Crestor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 41.0% - (5 of 12 people)
  • 60+: 68.0% - (13 of 19 people)
Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 71.0% - (5 of 7 people)
  • 50-59: 61.0% - (8 of 13 people)
  • 60+: 29.0% - (5 of 17 people)

Most common drug interactions over time *:

< 1 month:
  • oedema peripheral
  • weight increased
  • drug ineffective
  • insomnia
  • agitation
  • blood pressure increased
  • palpitations
  • arrhythmia
  • heart rate increased
  • localised oedema
1 - 6 months:
  • dizziness
  • weight increased
  • drug ineffective
  • fall
  • headache
  • nausea
  • pain
  • diarrhoea
  • dyspnoea
  • insomnia
6 - 12 months:
  • dizziness
  • fall
  • somnolence
  • liver disorder
  • oedema peripheral
  • depression
  • pain in extremity
  • asthenia
  • pain
  • amnesia
1 - 2 years:
  • hepatitis cholestatic
  • pain
  • asthenia
  • drug ineffective
  • gait disturbance
  • muscular weakness
  • pain in extremity
  • activities of daily living impaired
  • headache
  • hepatic enzyme increased
2 - 5 years:
  • pain
  • cardiac failure congestive
  • drug ineffective
  • neuropathy peripheral
  • feeling abnormal
  • bladder cancer
  • dyspnoea
  • hyperglycaemia
  • oral candidiasis
  • platelet count decreased
5 - 10 years:
  • pain
  • carpal tunnel syndrome
  • dyspepsia
  • dyspnoea
  • fall
  • general physical health deterioration
  • nerve injury
  • trigger finger
  • insomnia
  • nausea
10+ years:
  • cough
  • dizziness
  • chills
  • cold sweat
  • hypotension
  • nausea
  • pain
  • anaemia
  • eye disorder
  • fibromyalgia
not specified:
  • pain
  • drug ineffective
  • nausea
  • dyspnoea
  • malaise
  • headache
  • dizziness
  • pain in extremity
  • fall
  • weight increased

Most common drug interactions by gender *:

female:
  • pain
  • drug ineffective
  • weight increased
  • pain in extremity
  • nausea
  • headache
  • fall
  • dizziness
  • insomnia
  • malaise
male:
  • pain
  • drug ineffective
  • dizziness
  • dyspnoea
  • nausea
  • malaise
  • weight increased
  • fall
  • headache
  • pain in extremity

Most common drug interactions by age *:

0-1:
  • blood urine present
  • dyspnoea
  • gout
  • iron deficiency anaemia
  • metabolic disorder
  • myopathy
  • renal failure acute
  • rhabdomyolysis
10-19:
  • arthropathy
  • bone disorder
  • bone pain
  • cataract
  • convulsion
  • depression
  • fracture delayed union
  • humerus fracture
  • osteoporosis
  • squamous cell carcinoma
20-29:
  • drug ineffective
  • liver injury
  • procedural pain
  • infusion related reaction
  • migraine
  • agoraphobia
  • anhedonia
  • anxiety
  • back pain
  • brachial plexus injury
30-39:
  • intervertebral disc protrusion
  • dyspnoea
  • pain
  • cholecystitis acute
  • cystitis
  • dyspnoea exertional
  • hyponatraemia
  • lumbar spinal stenosis
  • venous thrombosis
  • diarrhoea
40-49:
  • pain
  • dizziness
  • weight increased
  • somnolence
  • drug ineffective
  • dyspnoea
  • headache
  • nausea
  • arthralgia
  • diarrhoea
50-59:
  • pain
  • drug ineffective
  • malaise
  • headache
  • pain in extremity
  • dyspnoea
  • nausea
  • vomiting
  • anxiety
  • weight increased
60+:
  • pain
  • drug ineffective
  • fall
  • dizziness
  • weight increased
  • asthenia
  • headache
  • insomnia
  • dyspnoea
  • pain in extremity

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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