Review: taking Crestor and Lyrica together


Summary

Drug interactions are reported among people who take Crestor and Lyrica together. This review analyzes the effectiveness and drug interactions between Crestor and Lyrica. It is created by eHealthMe based on reports of 1,775 people who take the same drugs from FDA and social media, and is updated regularly.

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Crestor

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Crestor 69,690 users)

Lyrica

Lyrica has active ingredients of pregabalin. It is often used in fibromyalgia. (latest outcomes from Lyrica 82,030 users)

On Aug, 19, 2016

1,775 people who take Crestor, Lyrica are studied.


Number of reports submitted per year:

Crestor and Lyrica drug interactions.

Drug effectiveness over time:

Crestor:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 85.0% - (6 of 7 people)
  • 2 - 5 years: 50.0% - (5 of 10 people)
  • 5 - 10 years: 56.0% - (9 of 16 people)
  • 10+ years: 100.0% - (2 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Lyrica:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 30.0% - (3 of 10 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 37.0% - (3 of 8 people)
  • 2 - 5 years: 63.0% - (7 of 11 people)
  • 5 - 10 years: 80.0% - (4 of 5 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Crestor:
  • female: 56.0% - (14 of 25 people)
  • male: 47.0% - (8 of 17 people)
Lyrica:
  • female: 40.0% - (10 of 25 people)
  • male: 60.0% - (9 of 15 people)

Drug effectiveness by age:

Crestor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 37.0% - (3 of 8 people)
  • 50-59: 41.0% - (5 of 12 people)
  • 60+: 68.0% - (13 of 19 people)
Lyrica:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 71.0% - (5 of 7 people)
  • 50-59: 61.0% - (8 of 13 people)
  • 60+: 29.0% - (5 of 17 people)

Most common drug interactions over time *:

< 1 month:
  • oedema peripheral
  • drug ineffective
  • weight increased
  • insomnia
  • agitation
  • blood pressure increased
  • palpitations
  • arrhythmia
  • heart rate increased
  • localised oedema
1 - 6 months:
  • dizziness
  • headache
  • weight increased
  • drug ineffective
  • dyspnoea
  • pain
  • renal failure acute
  • diarrhoea
  • rhabdomyolysis
  • withdrawal syndrome
6 - 12 months:
  • oedema peripheral
  • depression
  • fall
  • arthralgia
  • arthritis
  • asthenia
  • bone disorder
  • osteoarthritis
  • amnesia
  • anxiety
1 - 2 years:
  • hepatitis cholestatic
  • asthenia
  • drug ineffective
  • pain
  • headache
  • hepatic enzyme increased
  • muscular weakness
  • activities of daily living impaired
  • gait disturbance
  • migraine
2 - 5 years:
  • pain
  • headache
  • drug ineffective
  • hypoaesthesia
  • nausea
  • vomiting
  • arthralgia
  • dizziness
  • fall
  • feeling abnormal
5 - 10 years:
  • insomnia
  • chest pain
  • drug ineffective
  • edema - peripheral, peripheral edema
  • headache
  • hyperhidrosis
  • muscle cramps
  • muscle spasms
  • pain
  • syncope vasovagal
10+ years:
  • chills
  • cold sweat
  • cough
  • dizziness
  • hypotension
  • nausea
  • anaemia
  • abdominal pain upper
  • body height decreased
  • cataract
not specified:
  • pain
  • drug ineffective
  • dyspnoea
  • dizziness
  • asthenia
  • nausea
  • weight increased
  • headache
  • pain in extremity
  • fall

Most common drug interactions by gender *:

female:
  • pain
  • drug ineffective
  • weight increased
  • headache
  • asthenia
  • fall
  • dyspnoea
  • pain in extremity
  • oedema peripheral
  • dizziness
male:
  • dyspnoea
  • dizziness
  • pain
  • renal failure acute
  • drug ineffective
  • nausea
  • weight increased
  • asthenia
  • malaise
  • headache

Most common drug interactions by age *:

0-1:
  • blood urine present
  • dyspnoea
  • gout
  • iron deficiency anaemia
  • metabolic disorder
  • myopathy
  • renal failure acute
  • rhabdomyolysis
10-19:
  • fall
  • gingival bleeding
  • soft tissue necrosis
  • weight increased
  • arthropathy
  • bone disorder
  • bone pain
  • cataract
  • convulsion
  • depression
20-29:
  • infusion related reaction
  • drug ineffective
  • liver injury
  • procedural pain
  • anhedonia
  • anxiety
  • back pain
  • cerebrovascular accident
  • diabetes mellitus inadequate control
  • diabetic ketoacidosis
30-39:
  • pain
  • injury
  • intervertebral disc protrusion
  • abdominal pain upper
  • chest pain
  • dyspnoea
  • anxiety
  • arthropathy
  • asthenia
  • cholecystitis chronic
40-49:
  • weight increased
  • pain
  • arthralgia
  • dizziness
  • diarrhoea
  • dyspnoea
  • somnolence
  • headache
  • nausea
  • withdrawal syndrome
50-59:
  • pain
  • drug ineffective
  • renal failure acute
  • malaise
  • pain in extremity
  • anxiety
  • nausea
  • dyspnoea
  • weight increased
  • dizziness
60+:
  • pain
  • drug ineffective
  • weight increased
  • asthenia
  • dyspnoea
  • fall
  • dizziness
  • diarrhoea
  • headache
  • insomnia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Lyrica (pregabalin) is often used to treat fibromyalgia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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