Review: taking Crestor and Metformin together


Summary

Drug interactions are reported among people who take Crestor and Metformin together. This review analyzes the effectiveness and drug interactions between Crestor and Metformin. It is created by eHealthMe based on reports of 5,504 people who take the same drugs from FDA and social media, and is updated regularly.

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Crestor

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Crestor 57,941 users)

Metformin

Metformin has active ingredients of metformin. It is often used in diabetes. (latest outcomes from Metformin 99,379 users)

On Jul, 20, 2016

5,504 people who take Crestor, Metformin are studied.


Number of reports submitted per year:

Crestor and Metformin drug interactions.

Drug effectiveness over time:

Crestor:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 23.0% - (6 of 26 people)
  • 6 - 12 months: 57.0% - (16 of 28 people)
  • 1 - 2 years: 58.0% - (33 of 56 people)
  • 2 - 5 years: 79.0% - (88 of 111 people)
  • 5 - 10 years: 59.0% - (35 of 59 people)
  • 10+ years: 88.0% - (8 of 9 people)
  • not specified: 100.0% - (1 of 1 people)
Metformin:
  • < 1 month: 40.0% - (4 of 10 people)
  • 1 - 6 months: 8.0% - (2 of 25 people)
  • 6 - 12 months: 47.0% - (8 of 17 people)
  • 1 - 2 years: 34.0% - (25 of 72 people)
  • 2 - 5 years: 42.0% - (38 of 90 people)
  • 5 - 10 years: 50.0% - (30 of 59 people)
  • 10+ years: 41.0% - (17 of 41 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Crestor:
  • female: 66.0% - (91 of 136 people)
  • male: 61.0% - (96 of 157 people)
Metformin:
  • female: 46.0% - (71 of 152 people)
  • male: 32.0% - (53 of 163 people)

Drug effectiveness by age:

Crestor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 4 people)
  • 40-49: 55.0% - (30 of 54 people)
  • 50-59: 68.0% - (74 of 108 people)
  • 60+: 65.0% - (83 of 127 people)
Metformin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 42.0% - (27 of 63 people)
  • 50-59: 36.0% - (41 of 113 people)
  • 60+: 41.0% - (55 of 131 people)

Most common drug interactions over time *:

< 1 month:
  • myalgia
  • renal failure acute
  • headache
  • muscle spasms
  • arthralgia
  • feeling abnormal
  • hepatic failure
  • rhabdomyolysis
  • blood creatine phosphokinase increased
  • dyspnoea
1 - 6 months:
  • myalgia
  • optic neuritis
  • dizziness
  • blood creatine phosphokinase increased
  • diabetes mellitus
  • nausea
  • rhabdomyolysis
  • blood cholesterol increased
  • renal impairment
  • vomiting
6 - 12 months:
  • liver injury
  • myalgia
  • pain in extremity
  • dizziness
  • abdominal pain
  • cytolytic hepatitis
  • fatigue
  • vomiting
  • asthenia
  • autoimmune hepatitis
1 - 2 years:
  • myalgia
  • high density lipoprotein decreased
  • liver injury
  • leukocytoclastic vasculitis
  • elevated mood
  • fatigue
  • dizziness
  • gamma-glutamyltransferase increased
  • headache
  • hepatic function abnormal
2 - 5 years:
  • memory impairment
  • chest pain
  • dizziness
  • alopecia
  • myocardial infarction
  • renal failure acute
  • arterial occlusive disease
  • fatigue
  • thrombocytopenia
  • cardiac disorder
5 - 10 years:
  • lactic acidosis
  • renal failure acute
  • hepatic failure
  • myocardial ischaemia
  • hypoglycaemia
  • cardiac failure congestive
  • ascites
  • cardiogenic shock
  • malignant neoplasm progression
  • muscle cramps
10+ years:
  • erectile dysfunction
  • impotence
  • intracranial pressure increased
  • migraine
  • pulmonary hypertension
  • diabetes
  • diarrhea associated with medications
  • dizziness
  • fibromuscular dysplasia
  • hot flashes
not specified:
  • nausea
  • blood glucose increased
  • dyspnoea
  • weight decreased
  • fatigue
  • pain
  • pain in extremity
  • renal failure acute
  • myalgia
  • diarrhoea

Most common drug interactions by gender *:

female:
  • nausea
  • myalgia
  • pain in extremity
  • weight decreased
  • pain
  • diarrhoea
  • blood glucose increased
  • dyspnoea
  • fatigue
  • renal failure acute
male:
  • blood glucose increased
  • myocardial infarction
  • nausea
  • dyspnoea
  • fatigue
  • weight decreased
  • flushing
  • renal failure acute
  • dizziness
  • headache

Most common drug interactions by age *:

0-1:
  • abdominal pain
  • cytolytic hepatitis
  • diffuse alveolar damage
  • ejaculation failure
  • myalgia
  • abasia
  • anomaly of external ear congenital
  • asthenia
  • autoimmune hepatitis
  • blood cholesterol increased
2-9:
  • adrenal mass
10-19:
  • abdominal pain
  • diabetes mellitus inadequate control
  • type 2 diabetes mellitus
  • upper respiratory tract infection
  • urinary tract infection
20-29:
  • diabetes mellitus
  • chest pain
  • dizziness
  • cardiac arrest
  • diarrhoea
  • drug exposure during pregnancy
  • fatigue
  • fungal infection
  • headache
  • hypertension
30-39:
  • type 2 diabetes mellitus
  • weight decreased
  • fatigue
  • muscle spasms
  • pain
  • dyskinesia
  • convulsion
  • dysphagia
  • gastrooesophageal reflux disease
  • injury
40-49:
  • nausea
  • diarrhoea
  • pain
  • myocardial infarction
  • chest pain
  • diabetes mellitus
  • arthralgia
  • blood glucose increased
  • weight increased
  • dizziness
50-59:
  • renal failure acute
  • nausea
  • myocardial infarction
  • weight decreased
  • headache
  • blood glucose increased
  • fatigue
  • weight increased
  • myalgia
  • vomiting
60+:
  • blood glucose increased
  • dyspnoea
  • nausea
  • myalgia
  • renal failure acute
  • asthenia
  • fatigue
  • weight decreased
  • dizziness
  • pain in extremity

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Metformin (metformin) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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