Review: taking Crestor and Metformin together


Summary

Drug interactions are reported among people who take Crestor and Metformin together. This review analyzes the effectiveness and drug interactions between Crestor and Metformin. It is created by eHealthMe based on reports of 9,341 people who take the same drugs from FDA and social media, and is updated regularly.

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Crestor

Crestor has active ingredients of rosuvastatin calcium. It is often used in high blood cholesterol. (latest outcomes from Crestor 90,212 users)

Metformin

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. (latest outcomes from Metformin 174,670 users)

On Sep, 17, 2016

9,341 people who take Crestor, Metformin are studied.


Number of reports submitted per year:

Crestor and Metformin drug interactions.

Drug effectiveness over time:

Crestor:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 24.0% - (6 of 25 people)
  • 6 - 12 months: 52.0% - (11 of 21 people)
  • 1 - 2 years: 60.0% - (25 of 41 people)
  • 2 - 5 years: 68.0% - (50 of 73 people)
  • 5 - 10 years: 59.0% - (26 of 44 people)
  • 10+ years: 85.0% - (6 of 7 people)
  • not specified: 100.0% - (1 of 1 people)
Metformin:
  • < 1 month: 44.0% - (4 of 9 people)
  • 1 - 6 months: 4.0% - (1 of 23 people)
  • 6 - 12 months: 38.0% - (5 of 13 people)
  • 1 - 2 years: 34.0% - (16 of 47 people)
  • 2 - 5 years: 39.0% - (26 of 66 people)
  • 5 - 10 years: 46.0% - (21 of 45 people)
  • 10+ years: 34.0% - (9 of 26 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Crestor:
  • female: 61.0% - (59 of 96 people)
  • male: 55.0% - (66 of 119 people)
Metformin:
  • female: 41.0% - (44 of 106 people)
  • male: 30.0% - (38 of 124 people)

Drug effectiveness by age:

Crestor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 4 people)
  • 40-49: 48.0% - (21 of 43 people)
  • 50-59: 65.0% - (51 of 78 people)
  • 60+: 58.0% - (53 of 90 people)
Metformin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 34.0% - (16 of 47 people)
  • 50-59: 37.0% - (31 of 82 people)
  • 60+: 36.0% - (34 of 93 people)

Most common drug interactions over time *:

< 1 month:
  • myalgia
  • renal failure acute
  • headache
  • muscle spasms
  • nausea
  • dyspnoea
  • arthralgia
  • diabetes mellitus
  • feeling abnormal
  • pain
1 - 6 months:
  • myalgia
  • nausea
  • rhabdomyolysis
  • diabetes mellitus
  • dizziness
  • blood creatine phosphokinase increased
  • optic neuritis
  • blood cholesterol increased
  • vomiting
  • drug ineffective
6 - 12 months:
  • myalgia
  • liver injury
  • nausea
  • pain in extremity
  • fatigue
  • vomiting
  • abdominal pain
  • headache
  • dizziness
  • diarrhoea
1 - 2 years:
  • myalgia
  • liver injury
  • high density lipoprotein decreased
  • fatigue
  • leukocytoclastic vasculitis
  • elevated mood
  • memory impairment
  • pain
  • blood cholesterol increased
  • dizziness
2 - 5 years:
  • chest pain
  • fatigue
  • myocardial infarction
  • dizziness
  • memory impairment
  • muscle spasms
  • renal failure acute
  • weight decreased
  • diarrhoea
  • alopecia
5 - 10 years:
  • hypoglycaemia
  • fatigue
  • dizziness
  • renal failure acute
  • cardiac failure congestive
  • diarrhoea
  • adverse event
  • lactic acidosis
  • myalgia
  • weight decreased
10+ years:
  • erectile dysfunction
  • impotence
  • pain
  • intracranial pressure increased
  • abdominal pain upper
  • blood triglycerides increased
  • fall
  • gastric disorder
  • gastric ulcer
  • hyperglycaemia
not specified:
  • nausea
  • fatigue
  • blood glucose increased
  • weight decreased
  • dyspnoea
  • drug ineffective
  • diarrhoea
  • pain
  • dizziness
  • fall

Most common drug interactions by gender *:

female:
  • nausea
  • weight decreased
  • fatigue
  • pain
  • blood glucose increased
  • myalgia
  • diarrhoea
  • drug ineffective
  • dyspnoea
  • fall
male:
  • nausea
  • blood glucose increased
  • fatigue
  • weight decreased
  • dyspnoea
  • drug ineffective
  • myocardial infarction
  • dizziness
  • diarrhoea
  • headache

Most common drug interactions by age *:

0-1:
  • abdominal pain
  • cytolytic hepatitis
  • diffuse alveolar damage
  • ejaculation failure
  • myalgia
  • abasia
  • anomaly of external ear congenital
  • asthenia
  • autoimmune hepatitis
  • blood cholesterol increased
2-9:
  • adrenal mass
  • diabetes mellitus inadequate control
  • disorientation
  • erythema multiforme
  • foot fracture
  • hyperlipidaemia
  • hypertension
  • hypothyroidism
  • joint swelling
  • musculoskeletal pain
10-19:
  • drug ineffective
  • nausea
  • abdominal pain upper
  • blood cholesterol increased
  • ear infection
  • gastrooesophageal reflux disease
  • pharyngitis
  • arthritis
  • syncope
  • type 2 diabetes mellitus
20-29:
  • dyspnoea
  • drug ineffective
  • dizziness
  • headache
  • nausea
  • fall
  • fatigue
  • gait disturbance
  • liver injury
  • pain
30-39:
  • type 2 diabetes mellitus
  • weight decreased
  • malaise
  • fatigue
  • pain
  • gastrooesophageal reflux disease
  • convulsion
  • sinus tachycardia
  • injury
  • muscle spasms
40-49:
  • nausea
  • pain
  • diabetes mellitus
  • diarrhoea
  • chest pain
  • type 2 diabetes mellitus
  • myocardial infarction
  • headache
  • blood glucose increased
  • dyspnoea
50-59:
  • nausea
  • myocardial infarction
  • blood glucose increased
  • weight decreased
  • headache
  • fatigue
  • drug ineffective
  • renal failure acute
  • diarrhoea
  • vomiting
60+:
  • fatigue
  • nausea
  • dyspnoea
  • blood glucose increased
  • weight decreased
  • diarrhoea
  • myalgia
  • asthenia
  • dizziness
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Crestor (rosuvastatin calcium) is often used to treat high blood cholesterol. Metformin (metformin hydrochloride) is often used to treat diabetes. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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