Review: taking Cymbalta and Gabapentin together


Summary

Drug interactions are reported among people who take Cymbalta and Gabapentin together. This review analyzes the effectiveness and drug interactions between Cymbalta and Gabapentin. It is created by eHealthMe based on reports of 6,449 people who take the same drugs from FDA and social media, and is updated regularly.

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Cymbalta

Cymbalta has active ingredients of duloxetine hydrochloride. It is often used in depression. (latest outcomes from Cymbalta 58,912 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 52,972 users)

On Aug, 26, 2016

6,449 people who take Cymbalta, Gabapentin are studied.


Number of reports submitted per year:

Cymbalta and Gabapentin drug interactions.

Drug effectiveness over time:

Cymbalta:
  • < 1 month: 11.0% - (2 of 18 people)
  • 1 - 6 months: 28.0% - (19 of 67 people)
  • 6 - 12 months: 33.0% - (18 of 53 people)
  • 1 - 2 years: 27.0% - (17 of 62 people)
  • 2 - 5 years: 44.0% - (34 of 76 people)
  • 5 - 10 years: 35.0% - (10 of 28 people)
  • 10+ years: 50.0% - (5 of 10 people)
  • not specified: 40.0% - (2 of 5 people)
Gabapentin:
  • < 1 month: 25.0% - (5 of 20 people)
  • 1 - 6 months: 22.0% - (13 of 57 people)
  • 6 - 12 months: 28.0% - (15 of 52 people)
  • 1 - 2 years: 24.0% - (16 of 65 people)
  • 2 - 5 years: 32.0% - (25 of 77 people)
  • 5 - 10 years: 31.0% - (12 of 38 people)
  • 10+ years: 26.0% - (4 of 15 people)
  • not specified: 25.0% - (1 of 4 people)

Drug effectiveness by gender:

Cymbalta:
  • female: 35.0% - (93 of 262 people)
  • male: 24.0% - (14 of 57 people)
Gabapentin:
  • female: 28.0% - (77 of 267 people)
  • male: 22.0% - (14 of 61 people)

Drug effectiveness by age:

Cymbalta:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 28.0% - (6 of 21 people)
  • 30-39: 26.0% - (19 of 72 people)
  • 40-49: 36.0% - (34 of 92 people)
  • 50-59: 38.0% - (27 of 71 people)
  • 60+: 32.0% - (20 of 61 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 20.0% - (4 of 20 people)
  • 30-39: 26.0% - (21 of 78 people)
  • 40-49: 29.0% - (28 of 94 people)
  • 50-59: 26.0% - (19 of 71 people)
  • 60+: 29.0% - (19 of 64 people)

Most common drug interactions over time *:

< 1 month:
  • headache
  • nausea
  • dizziness
  • drug ineffective
  • pain
  • somnolence
  • feeling abnormal
  • insomnia
  • not breathing
  • pain - neck
1 - 6 months:
  • dizziness
  • fall
  • drug ineffective
  • headache
  • loss of consciousness
  • pneumonia
  • abdominal pain
  • aspartate aminotransferase increased
  • alanine aminotransferase increased
  • fatigue
6 - 12 months:
  • drug ineffective
  • anxiety
  • dizziness
  • disturbance in attention
  • erectile dysfunction
  • fine motor delay
  • tooth disorder
  • depression
  • insomnia
  • pain
1 - 2 years:
  • drug ineffective
  • type 2 diabetes mellitus
  • fibromyalgia
  • erectile dysfunction
  • nausea
  • tinnitus
  • anxiety
  • pain
  • disturbance in attention
  • neuropathy peripheral
2 - 5 years:
  • pain
  • depression
  • pancreatitis
  • sleep apnoea syndrome
  • tardive dyskinesia
  • suicidal ideation
  • convulsion
  • insomnia
  • renal failure
  • road traffic accident
5 - 10 years:
  • rash
  • open wound
  • swelling of the ankles - feet - legs
  • suicidal ideation
  • depression
  • diabetes mellitus
  • fatigue
  • drug ineffective
  • high blood cholesterol
  • high blood sugar
10+ years:
  • swollen tongue
  • eczema eyelids
  • high blood cholesterol
  • high blood sugar
  • hyperkalaemia
  • swelling face
  • restless leg syndrome
  • anxiety
  • chf
  • deep vein thrombosis
not specified:
  • pain
  • nausea
  • fatigue
  • depression
  • drug ineffective
  • fall
  • anxiety
  • headache
  • dizziness
  • pain in extremity

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fall
  • fatigue
  • anxiety
  • drug ineffective
  • headache
  • depression
  • pain in extremity
  • dizziness
male:
  • pain
  • fatigue
  • depression
  • nausea
  • drug ineffective
  • vomiting
  • anxiety
  • dizziness
  • headache
  • neuropathy peripheral

Most common drug interactions by age *:

0-1:
  • blood cholesterol increased
  • gallbladder operation
  • sensation of foreign body
  • type 2 diabetes mellitus
  • agitation
  • cardiac arrest
  • diabetes mellitus inadequate control
  • hypertension
  • ketoacidosis
  • pancreatitis acute
2-9:
  • abasia
  • arthralgia
  • bursitis
  • femur fracture
  • pain in extremity
  • stress fracture
  • cardiac disorder
10-19:
  • pain
  • gallbladder disorder
  • depression
  • suicidal ideation
  • cholecystitis chronic
  • pancreatitis
  • sphincter of oddi dysfunction
  • abdominal pain
  • alanine aminotransferase increased
  • arthralgia
20-29:
  • headache
  • vomiting
  • nausea
  • pain
  • dizziness
  • dyspnoea
  • fatigue
  • insomnia
  • deep vein thrombosis
  • confusional state
30-39:
  • fatigue
  • nausea
  • headache
  • pain
  • depression
  • dizziness
  • anxiety
  • drug ineffective
  • abdominal pain
  • weight increased
40-49:
  • pain
  • nausea
  • headache
  • fatigue
  • depression
  • type 2 diabetes mellitus
  • drug ineffective
  • anxiety
  • neuropathy peripheral
  • hypoaesthesia
50-59:
  • pain
  • nausea
  • anxiety
  • fall
  • arthralgia
  • drug ineffective
  • fatigue
  • diarrhoea
  • dizziness
  • depression
60+:
  • pain
  • fall
  • nausea
  • fatigue
  • pain in extremity
  • anxiety
  • back pain
  • dizziness
  • headache
  • depression

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Cymbalta (duloxetine hydrochloride) is often used to treat depression. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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