Depakote and Trazodone hydrochloride drug interactions - from FDA reports


Summary

Drug interactions are reported among people who take Depakote and Trazodone hydrochloride together. This review analyzes the effectiveness and drug interactions between Depakote and Trazodone hydrochloride. It is created by eHealthMe based on reports of 1,987 people who take the same drugs from FDA, and is updated regularly.

What to expect?

If you take Depakote and Trazodone hydrochloride, find out what symptoms you could have in 1 year or longer.

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Depakote

Depakote has active ingredients of divalproex sodium. It is often used in bipolar disorder. (latest outcomes from Depakote 39,085 users)

Trazodone Hydrochloride

Trazodone hydrochloride has active ingredients of trazodone hydrochloride. It is often used in insomnia. (latest outcomes from Trazodone hydrochloride 8,910 users)

On Feb, 10, 2017

1,987 people who take Depakote, Trazodone Hydrochloride are studied.


Number of reports submitted per year:

Depakote and Trazodone hydrochloride drug interactions.

Most common drug interactions over time *:

< 1 month:
  • blood cholesterol increased
  • blood triglycerides increased
  • haematocrit decreased
  • haemoglobin decreased
  • blood glucose increased
  • confusional state
  • granulocytopenia
  • overdose
  • chest pain
  • ammonia increased
1 - 6 months:
  • aggression
  • drug exposure during pregnancy
  • ventricular septal defect
  • atrial septal defect
  • pain
  • anaemia
  • anxiety
  • apnoea
  • foetal distress syndrome
  • respiratory distress
6 - 12 months:
  • type 2 diabetes mellitus
  • pain
  • diabetes mellitus
  • nausea
  • anxiety
  • back pain
  • cerebral infarction
  • emotional distress
  • gastrooesophageal reflux disease
  • general physical health deterioration
1 - 2 years:
  • back pain
  • type 2 diabetes mellitus
  • aggression
  • blood cholesterol increased
  • diabetic neuropathy
  • neuropathy peripheral
  • sleep disorder
  • affective disorder
  • appendicitis
  • blood triglycerides increased
2 - 5 years:
  • drug exposure during pregnancy
  • ventricular septal defect
  • atrial septal defect
  • type 2 diabetes mellitus
  • respiratory distress
  • anaemia
  • apnoea
  • diabetes mellitus
  • foetal distress syndrome
  • anxiety
5 - 10 years:
  • obesity
  • type 2 diabetes mellitus
  • back pain
  • diabetes mellitus
  • nausea
  • pancreatitis
  • adverse drug reaction
  • abdominal pain upper
  • hyperglycaemia
  • fatigue
10+ years:
  • weight increased
  • diabetes mellitus inadequate control
  • blood glucose increased
  • diabetic neuropathy
  • diabetic retinopathy
  • obesity
  • proteinuria
  • renal disorder
  • blood cholesterol increased
  • diabetic eye disease
not specified:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • nausea
  • weight increased
  • fatigue
  • depression
  • headache
  • dizziness
  • suicidal ideation
  • tremor

Most common drug interactions by gender *:

female:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • nausea
  • headache
  • weight increased
  • depression
  • anxiety
  • dizziness
  • pain
  • fatigue
male:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • fatigue
  • aggression
  • suicidal ideation
  • weight increased
  • agitation
  • tremor
  • nausea
  • chest pain

Most common drug interactions by age *:

0-1:
  • foetal exposure during pregnancy
  • aggression
  • convulsion
  • muscular weakness
  • tremor
  • cardiac tamponade
  • chronic kidney disease
  • chronic respiratory failure
  • congenital tracheomalacia
  • deep vein thrombosis
2-9:
  • aggression
  • intentional self-injury
  • screaming
  • suicidal behaviour
  • dyspnoea
  • agitation
  • bipolar disorder
  • bite
  • convulsion
  • depression
10-19:
  • aggression
  • affective disorder
  • agitation
  • suicidal ideation
  • sleep disorder
  • weight increased
  • neuroleptic malignant syndrome
  • compartment syndrome
  • drug administration error
  • extremity necrosis
20-29:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • weight increased
  • dizziness
  • blood cholesterol increased
  • headache
  • suicidal ideation
  • abdominal pain
  • anxiety
  • anger
30-39:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • nausea
  • obesity
  • weight increased
  • hypertension
  • pain
  • depression
  • vision blurred
  • blood cholesterol increased
40-49:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • nausea
  • neuropathy peripheral
  • fatigue
  • blood cholesterol increased
  • weight increased
  • chest pain
  • pain
  • blood triglycerides increased
50-59:
  • type 2 diabetes mellitus
  • diabetes mellitus
  • nausea
  • insomnia
  • dizziness
  • depression
  • overdose
  • obesity
  • neuropathy peripheral
  • tremor
60+:
  • nausea
  • fatigue
  • headache
  • fall
  • dizziness
  • tremor
  • vomiting
  • myocardial infarction
  • confusional state
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Depakote and Trazodone hydrochloride?

Interactions between Depakote and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

Interactions between Trazodone hydrochloride and drugs from A to Z

a b c d e f g h i j k l m n o p q r s t u v w x y z

On eHealthMe, Depakote (divalproex sodium) is often used to treat bipolar disorder. Trazodone hydrochloride (trazodone hydrochloride) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

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