Review: taking Diclofenac sodium and Tylenol together


Summary

Drug interactions are reported among people who take Diclofenac sodium and Tylenol together. This review analyzes the effectiveness and drug interactions between Diclofenac sodium and Tylenol. It is created by eHealthMe based on reports of 4,039 people who take the same drugs from FDA and social media, and is updated regularly.

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Diclofenac Sodium

Diclofenac sodium has active ingredients of diclofenac sodium. It is often used in rheumatoid arthritis. (latest outcomes from Diclofenac sodium 16,279 users)

Tylenol

Tylenol has active ingredients of acetaminophen. It is often used in pain. (latest outcomes from Tylenol 81,872 users)

On Sep, 17, 2016

4,039 people who take Diclofenac Sodium, Tylenol are studied.


Number of reports submitted per year:

Diclofenac sodium and Tylenol drug interactions.

Drug effectiveness over time:

Diclofenac Sodium:
  • < 1 month: 36.0% - (4 of 11 people)
  • 1 - 6 months: 0.0% - (0 of 7 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 25.0% - (1 of 4 people)
  • 5 - 10 years: 42.0% - (3 of 7 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 3 people)
Tylenol:
  • < 1 month: 18.0% - (2 of 11 people)
  • 1 - 6 months: 50.0% - (3 of 6 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 4 people)
  • 2 - 5 years: 25.0% - (1 of 4 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 42.0% - (3 of 7 people)
  • not specified: 50.0% - (1 of 2 people)

Drug effectiveness by gender:

Diclofenac Sodium:
  • female: 21.0% - (7 of 32 people)
  • male: 37.0% - (3 of 8 people)
Tylenol:
  • female: 32.0% - (10 of 31 people)
  • male: 22.0% - (2 of 9 people)

Drug effectiveness by age:

Diclofenac Sodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 0.0% - (0 of 4 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 0.0% - (0 of 11 people)
  • 50-59: 40.0% - (4 of 10 people)
  • 60+: 46.0% - (6 of 13 people)
Tylenol:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 9.0% - (1 of 11 people)
  • 50-59: 40.0% - (4 of 10 people)
  • 60+: 38.0% - (5 of 13 people)

Most common drug interactions over time *:

< 1 month:
  • pyrexia
  • nausea
  • vomiting
  • diarrhoea
  • renal failure acute
  • abdominal pain
  • anaemia
  • pneumonia
  • malaise
  • toxic epidermal necrolysis
1 - 6 months:
  • pulmonary embolism
  • nephrotic syndrome
  • malaise
  • deep vein thrombosis
  • constipation
  • nausea
  • renal failure
  • renal failure acute
  • vomiting
  • abdominal pain
6 - 12 months:
  • nausea
  • pyrexia
  • aplastic anaemia
  • asthenia
  • petechiae
  • vomiting
  • rhabdomyolysis
  • respiratory failure
  • hypotension
  • pneumonia
1 - 2 years:
  • aplastic anaemia
  • asthenia
  • oedema peripheral
  • petechiae
  • arthralgia
  • dehydration
  • diarrhoea
  • renal failure acute
  • urinary tract infection
  • depression
2 - 5 years:
  • gastrointestinal haemorrhage
  • anaemia
  • blood urea increased
  • faeces discoloured
  • haemoglobin decreased
  • blood count abnormal
  • vitamin b12 decreased
  • lower respiratory tract infection
  • paraesthesia
  • pseudomembranous colitis
5 - 10 years:
  • acute hepatic failure
  • conjunctival haemorrhage
  • hepatitis acute
  • liver function test abnormal
  • thrombosis
  • vomiting
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood albumin increased
  • blood alkaline phosphatase increased
10+ years:
  • hepatitis
  • alanine aminotransferase increased
  • drug administration error
  • fatigue
  • injection site erythema
  • injection site pruritus
  • multiple drug overdose
  • pancreatitis acute
  • swelling
  • weight increased
not specified:
  • nausea
  • pain
  • headache
  • arthralgia
  • diarrhoea
  • vomiting
  • pyrexia
  • dyspnoea
  • pain in extremity
  • fall

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • diarrhoea
  • vomiting
  • headache
  • pyrexia
  • arthralgia
  • fatigue
  • pain in extremity
  • fall
male:
  • nausea
  • pyrexia
  • renal failure acute
  • diarrhoea
  • dyspnoea
  • vomiting
  • anaemia
  • pain
  • arthralgia
  • hypotension

Most common drug interactions by age *:

0-1:
  • cardiac arrest
  • dyskinesia
  • oedema peripheral
  • respiratory arrest
  • vomiting
  • abdominal distension
  • flatulence
  • sudden death
  • developmental hip dysplasia
  • foetal exposure during pregnancy
2-9:
  • diarrhoea
  • renal failure acute
  • renal tubular necrosis
  • abdominal pain
  • accidental drug intake by child
  • skin discolouration
  • vomiting
  • cardiac arrest
  • chemical injury
  • blood pressure decreased
10-19:
  • vomiting
  • nausea
  • chest discomfort
  • malaise
  • intentional overdose
  • pallor
  • diarrhoea
  • syncope
  • blood glucose decreased
  • cyanosis
20-29:
  • vomiting
  • nausea
  • abdominal pain
  • tachycardia
  • convulsion
  • drug exposure during pregnancy
  • pyrexia
  • drug ineffective
  • loss of consciousness
  • dizziness
30-39:
  • nausea
  • diarrhoea
  • vomiting
  • pyrexia
  • arthralgia
  • dyspnoea
  • maternal exposure during pregnancy
  • abdominal pain
  • depression
  • pain
40-49:
  • pyrexia
  • nausea
  • headache
  • abdominal pain
  • chest pain
  • pain
  • diarrhoea
  • arthralgia
  • anxiety
  • cough
50-59:
  • headache
  • pain
  • nausea
  • arthralgia
  • diarrhoea
  • pain in extremity
  • pyrexia
  • vomiting
  • fatigue
  • back pain
60+:
  • nausea
  • pain
  • renal failure acute
  • dehydration
  • fall
  • dyspnoea
  • pyrexia
  • diarrhoea
  • confusional state
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Diclofenac sodium and Tylenol?

Can you answer these questions?

More questions for: Diclofenac sodium, Tylenol

You may be interested in these reviews

More reviews for: Diclofenac sodium, Tylenol

On eHealthMe, Diclofenac sodium (diclofenac sodium) is often used to treat rheumatoid arthritis. Tylenol (acetaminophen) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.