Review: taking Diflucan and Valtrex together


Summary

Drug interactions are reported among people who take Diflucan and Valtrex together. This review analyzes the effectiveness and drug interactions between Diflucan and Valtrex. It is created by eHealthMe based on reports of 1,501 people who take the same drugs from FDA and social media, and is updated regularly.

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Diflucan

Diflucan has active ingredients of fluconazole. It is often used in fungal infection. (latest outcomes from Diflucan 17,595 users)

Valtrex

Valtrex has active ingredients of valacyclovir hydrochloride. It is often used in herpes zoster. (latest outcomes from Valtrex 16,238 users)

On Jul, 27, 2016

1,501 people who take Diflucan, Valtrex are studied.


Number of reports submitted per year:

Diflucan and Valtrex drug interactions.

Drug effectiveness over time:

Diflucan:
  • < 1 month: 33.0% - (2 of 6 people)
  • 1 - 6 months: 100.0% - (2 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 2 people)
  • not specified: 0.0% - (0 of 0 people)
Valtrex:
  • < 1 month: 50.0% - (2 of 4 people)
  • 1 - 6 months: 100.0% - (2 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (5 of 5 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Diflucan:
  • female: 40.0% - (4 of 10 people)
  • male: 100.0% - (2 of 2 people)
Valtrex:
  • female: 70.0% - (7 of 10 people)
  • male: 100.0% - (3 of 3 people)

Drug effectiveness by age:

Diflucan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (2 of 2 people)
  • 60+: 50.0% - (1 of 2 people)
Valtrex:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 100.0% - (1 of 1 people)
  • 20-29: 66.0% - (2 of 3 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 100.0% - (3 of 3 people)
  • 60+: 50.0% - (1 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • pneumonia
  • febrile neutropenia
  • renal failure acute
  • pyrexia
  • anaemia
  • rash
  • renal failure
  • sepsis
  • thrombocytopenia
  • acute graft versus host disease
1 - 6 months:
  • sepsis
  • thrombocytopenia
  • febrile neutropenia
  • pyrexia
  • white blood cell count decreased
  • haemoglobin decreased
  • inflammation
  • influenza
  • nausea
  • pneumonia viral
6 - 12 months:
  • pyrexia
  • graft versus host disease
  • blood alkaline phosphatase increased
  • gamma-glutamyltransferase increased
  • acute graft versus host disease
  • anxiety
  • cerebral toxoplasmosis
  • cholecystitis acute
  • cholelithiasis
  • depression
1 - 2 years:
  • hepatocellular injury
  • liver injury
  • drowsiness
2 - 5 years:
  • anaemia
  • anxiety
  • biliary dyskinesia
  • breath odour
  • cholecystitis chronic
  • dehydration
  • depression
  • gallbladder non-functioning
  • gambling
  • gastritis
5 - 10 years:
  • dehydration
  • drowsiness
  • gastritis
  • gastrooesophageal reflux disease
  • gerd
  • hepatic failure
  • herpes simplex
  • hiatus hernia
  • vomiting
  • weight decreased
10+ years:
  • abdominal distension
  • abdominal pain upper
  • depression
  • dizziness
  • drug ineffective
  • eating disorder
  • gastric disorder
  • hallucination, auditory
  • herpes zoster
  • insomnia
not specified:
  • pain
  • pyrexia
  • nausea
  • anxiety
  • vomiting
  • anaemia
  • diarrhoea
  • pneumonia
  • fatigue
  • osteonecrosis of jaw

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • anxiety
  • pyrexia
  • vomiting
  • diarrhoea
  • pneumonia
  • febrile neutropenia
  • anaemia
  • depression
male:
  • pyrexia
  • anaemia
  • pneumonia
  • fatigue
  • nausea
  • vomiting
  • febrile neutropenia
  • pain
  • thrombocytopenia
  • pancytopenia

Most common drug interactions by age *:

0-1:
  • back pain
  • blood cholesterol increased
  • blood triglycerides increased
  • bundle branch block right
  • cerumen impaction
  • chest pain
  • dizziness
  • fatigue
  • type 2 diabetes mellitus
2-9:
  • vomiting
  • diarrhoea
  • abdominal pain
  • abdominal tenderness
  • acidosis
  • blood amylase increased
  • blood creatinine increased
  • blood lactate dehydrogenase increased
  • bradycardia
  • cardiac arrest
10-19:
  • febrile neutropenia
  • blood bilirubin increased
  • platelet count decreased
  • renal failure acute
  • anxiety
  • blood creatinine increased
  • haemoglobin decreased
  • pneumonia
  • sepsis
  • diarrhoea
20-29:
  • nausea
  • diarrhoea
  • crohn's disease
  • chest pain
  • cholecystitis
  • abdominal pain
  • akinesia
  • gallbladder cholesterolosis
  • migraine
  • pineal gland cyst
30-39:
  • fatigue
  • anaemia
  • dehydration
  • dyspnoea
  • proctalgia
  • gastrointestinal haemorrhage
  • hyperglycaemia
  • multi-organ failure
  • neutropenia
  • haemoglobin decreased
40-49:
  • pain
  • pyrexia
  • anxiety
  • nausea
  • general physical health deterioration
  • osteonecrosis of jaw
  • anaemia
  • hypertension
  • vomiting
  • headache
50-59:
  • pyrexia
  • pain
  • anxiety
  • back pain
  • vomiting
  • neutropenia
  • pneumonia
  • anaemia
  • osteoarthritis
  • fatigue
60+:
  • pneumonia
  • pyrexia
  • febrile neutropenia
  • asthenia
  • nausea
  • thrombocytopenia
  • diarrhoea
  • hypokalaemia
  • fatigue
  • vomiting

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Diflucan (fluconazole) is often used to treat fungal infection. Valtrex (valacyclovir hydrochloride) is often used to treat herpes zoster. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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