Review: taking Dilantin and Isoniazid together


Summary

Drug interactions are reported among people who take Dilantin and Isoniazid together. This review analyzes the effectiveness and drug interactions between Dilantin and Isoniazid. It is created by eHealthMe based on reports of 105 people who take the same drugs from FDA and social media, and is updated regularly.

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Dilantin

Dilantin has active ingredients of phenytoin. It is often used in convulsion. (latest outcomes from Dilantin 4,823 users)

Isoniazid

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from Isoniazid 10,069 users)

On Sep, 27, 2016

105 people who take Dilantin, Isoniazid are studied.


Number of reports submitted per year:

Dilantin and Isoniazid drug interactions.

Most common drug interactions over time *:

< 1 month:
  • stevens-johnson syndrome
  • convulsion
  • acute graft versus host disease in intestine
  • acute graft versus host disease in liver
  • acute graft versus host disease in skin
  • altered state of consciousness
  • anaphylactoid reaction
  • blood lactate dehydrogenase increased
  • cardiac tamponade
  • constipation
1 - 6 months:
  • stevens-johnson syndrome
  • aplasia pure red cell
  • blood iron abnormal
  • meningioma
  • staphylococcal bacteraemia
  • anti-erythropoietin antibody positive
  • confusional state
  • therapeutic response decreased
  • anaemia
  • convulsion
6 - 12 months:
  • stevens-johnson syndrome
  • ankle fracture
  • convulsion
  • deafness
  • deep vein thrombosis
  • emotional disorder
  • mental disorder
  • oedema
  • pleurisy
  • sinus arrhythmia
not specified:
  • vomiting
  • renal impairment
  • cytomegalovirus infection
  • liver disorder
  • nystagmus
  • idiopathic pneumonia syndrome
  • mucosal inflammation
  • pulmonary haemorrhage
  • pulmonary hypertension
  • respiratory failure

Most common drug interactions by gender *:

female:
  • stevens-johnson syndrome
  • cytomegalovirus infection
  • liver disorder
  • renal impairment
  • idiopathic pneumonia syndrome
  • mucosal inflammation
  • pulmonary haemorrhage
  • pulmonary hypertension
  • respiratory failure
  • venoocclusive disease
male:
  • nystagmus
  • vomiting
  • ataxia
  • convulsion
  • optic neuritis
  • nausea
  • paradoxical drug reaction
  • confusional state
  • decreased appetite
  • dizziness

Most common drug interactions by age *:

2-9:
  • stevens-johnson syndrome
  • paradoxical drug reaction
  • cytomegalovirus infection
  • idiopathic pneumonia syndrome
  • liver disorder
  • mucosal inflammation
  • optic neuritis
  • pulmonary haemorrhage
  • pulmonary hypertension
  • renal impairment
10-19:
  • loss of consciousness
  • metabolic acidosis
  • suicide attempt
  • blood creatine phosphokinase increased
  • blood potassium decreased
  • coma
  • drug ineffective
  • dyskinesia
  • grand mal convulsion
  • haemodynamic instability
20-29:
  • vomiting
  • oedema
  • stevens-johnson syndrome
  • ataxia
  • gait disturbance
  • hepatitis
  • lip swelling
  • nystagmus
  • rash macular
  • swelling face
30-39:
  • convulsion
  • deafness
  • cerebral toxoplasmosis
  • deafness neurosensory
  • abortion spontaneous
  • bacterial sepsis
  • blood alkaline phosphatase nos increased
  • cerebellar ataxia
  • cytomegalovirus infection
  • deafness bilateral
40-49:
  • c-reactive protein increased
  • clavicle fracture
  • hepatic encephalopathy
  • hypokalaemia
  • pneumonia
  • pruritus
  • rectal prolapse
  • adenovirus infection
  • altered state of consciousness
  • bacterial sepsis
50-59:
  • stevens-johnson syndrome
  • grand mal convulsion
  • atrial fibrillation
  • cerebral haemorrhage
  • drug ineffective
  • liver function tests nos abnormal
  • nausea
60+:
  • confusional state
  • decreased appetite
  • dizziness
  • dysarthria
  • dysphagia
  • intention tremor
  • nausea
  • nystagmus
  • vomiting
  • ataxia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Dilantin (phenytoin) is often used to treat convulsion. Isoniazid (isoniazid) is often used to treat tuberculosis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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