Review: taking Dilantin and Isoniazid together


Summary

Drug interactions are reported among people who take Dilantin and Isoniazid together. This review analyzes the effectiveness and drug interactions between Dilantin and Isoniazid. It is created by eHealthMe based on reports of 62 people who take the same drugs from FDA and social media, and is updated regularly.

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Dilantin

Dilantin has active ingredients of phenytoin. It is often used in convulsion. (latest outcomes from Dilantin 20,084 users)

Isoniazid

Isoniazid has active ingredients of isoniazid. It is often used in tuberculosis. (latest outcomes from Isoniazid 7,596 users)

On Jul, 23, 2016

62 people who take Dilantin, Isoniazid are studied.


Number of reports submitted per year:

Dilantin and Isoniazid drug interactions.

Most common drug interactions over time *:

< 1 month:
  • stevens-johnson syndrome
  • multi-organ failure
  • pneumonia
  • post procedural complication
  • respiratory failure
  • sepsis
  • toxic epidermal necrolysis
  • cerebral haemorrhage
  • convulsion
  • septic shock
1 - 6 months:
  • meningioma
  • staphylococcal bacteraemia
  • anti-erythropoietin antibody positive
  • confusional state
  • stevens-johnson syndrome
  • therapeutic response decreased
  • anaemia
  • convulsion
  • aplasia pure red cell
  • blood iron abnormal
6 - 12 months:
  • stevens-johnson syndrome
  • convulsion
  • deafness
  • cerebral toxoplasmosis
  • deafness neurosensory
  • deafness bilateral
  • disseminated tuberculosis
  • hypoacusis
not specified:
  • optic neuritis
  • cytomegalovirus infection
  • idiopathic pneumonia syndrome
  • liver disorder
  • mucosal inflammation
  • pulmonary haemorrhage
  • pulmonary hypertension
  • renal impairment
  • respiratory failure
  • venoocclusive disease

Most common drug interactions by gender *:

female:
  • stevens-johnson syndrome
  • aplasia pure red cell
  • blood iron abnormal
  • cytomegalovirus infection
  • idiopathic pneumonia syndrome
  • liver disorder
  • meningioma
  • mucosal inflammation
  • pulmonary haemorrhage
  • pulmonary hypertension
male:
  • optic neuritis
  • convulsion
  • paradoxical drug reaction
  • blindness
  • deafness
  • pneumonia
  • septic shock
  • aids encephalopathy
  • anticonvulsant drug level decreased
  • c-reactive protein increased

Most common drug interactions by age *:

2-9:
  • optic neuritis
  • cytomegalovirus infection
  • idiopathic pneumonia syndrome
  • liver disorder
  • mucosal inflammation
  • pulmonary haemorrhage
  • pulmonary hypertension
  • renal impairment
  • respiratory failure
  • venoocclusive disease
10-19:
  • optic neuritis
  • vena cava thrombosis
30-39:
  • convulsion
  • deafness
  • cerebral toxoplasmosis
  • deafness neurosensory
  • blood alkaline phosphatase nos increased
  • cerebellar ataxia
  • deafness bilateral
  • depressed level of consciousness
  • disseminated tuberculosis
  • gamma-glutamyltransferase increased
40-49:
  • c-reactive protein increased
  • clavicle fracture
  • hypokalaemia
  • pneumonia
  • pruritus
  • rectal prolapse
  • altered state of consciousness
  • death
  • diabetes mellitus
  • diabetic neuropathy
50-59:
  • stevens-johnson syndrome
  • grand mal convulsion
  • atrial fibrillation
  • cerebral haemorrhage
  • drug ineffective
  • liver function tests nos abnormal
  • nausea
60+:
  • septic shock
  • aids encephalopathy
  • catheter related infection
  • hiv infection
  • pyrexia
  • staphylococcal infection
  • coma
  • fall
  • aspartate aminotransferase increased
  • cardiac failure congestive

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Dilantin (phenytoin) is often used to treat convulsion. Isoniazid (isoniazid) is often used to treat tuberculosis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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