Review: taking Dilaudid and Methotrexate sodium together


Summary

Drug interactions are reported among people who take Dilaudid and Methotrexate sodium together. This review analyzes the effectiveness and drug interactions between Dilaudid and Methotrexate sodium. It is created by eHealthMe based on reports of 799 people who take the same drugs from FDA and social media, and is updated regularly.

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Dilaudid

Dilaudid has active ingredients of hydromorphone hydrochloride. It is often used in pain. (latest outcomes from Dilaudid 16,492 users)

Methotrexate Sodium

Methotrexate sodium has active ingredients of methotrexate sodium. It is often used in rheumatoid arthritis. (latest outcomes from Methotrexate sodium 11,931 users)

On Sep, 10, 2016

799 people who take Dilaudid, Methotrexate Sodium are studied.


Number of reports submitted per year:

Dilaudid and Methotrexate sodium drug interactions.

Drug effectiveness over time:

Dilaudid:
  • < 1 month: 100.0% - (1 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Methotrexate Sodium:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 50.0% - (1 of 2 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Dilaudid:
  • female: 100.0% - (1 of 1 people)
  • male: 50.0% - (1 of 2 people)
Methotrexate Sodium:
  • female: 0.0% - (0 of 0 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Dilaudid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 50.0% - (1 of 2 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 100.0% - (1 of 1 people)
Methotrexate Sodium:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 1 people)

Most common drug interactions over time *:

< 1 month:
  • nausea
  • headache
  • arthritis
  • constipation
  • pain
  • arthralgia
  • somnolence
  • vomiting
  • blood glucose increased
  • fall
1 - 6 months:
  • arthralgia
  • arthritis
  • fatigue
  • insomnia
  • nausea
  • urinary retention
  • vomiting
  • arachnoiditis
  • arthropathy
  • blood glucose increased
6 - 12 months:
  • metastatic gastric cancer
  • dysphagia
  • dysphonia
  • gastric cancer
  • aphagia
  • arthralgia
  • cachexia
  • cellulitis
  • cerebrovascular accident
  • citrobacter infection
1 - 2 years:
  • rheumatoid arthritis
  • bone marrow failure
  • hepatic encephalopathy
  • liver disorder
  • pancytopenia
  • rash
  • renal failure acute
  • stomatitis
  • urinary tract infection
  • vertigo
2 - 5 years:
  • metastatic gastric cancer
  • arthralgia
  • dysphagia
  • dysphonia
  • gastric cancer
  • neuropathic pain
  • abortion spontaneous
  • angina pectoris
  • anxiety postoperative
  • aphagia
5 - 10 years:
  • arthralgia
  • herpes zoster
  • peripheral swelling
  • pneumonia viral
  • anaemia
  • arthritis
  • blood cholesterol increased
  • drug ineffective
  • fibromyalgia
  • joint swelling
10+ years:
  • hypertensive emergency
  • aortic valve incompetence
  • cardiac failure congestive
  • diastolic dysfunction
  • mitral valve incompetence
  • pulmonary valve incompetence
  • tricuspid valve incompetence
  • ventricular hypertrophy
  • abscess limb
  • arthralgia
not specified:
  • pain
  • nausea
  • fatigue
  • pyrexia
  • dyspnoea
  • anaemia
  • anxiety
  • arthralgia
  • diarrhoea
  • vomiting

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • arthralgia
  • oedema peripheral
  • dyspnoea
  • anxiety
  • anaemia
  • pneumonia
  • pyrexia
male:
  • pyrexia
  • abdominal pain
  • nausea
  • vomiting
  • fatigue
  • renal failure acute
  • headache
  • pain
  • colitis
  • weight decreased

Most common drug interactions by age *:

2-9:
  • hyperaesthesia
  • allodynia
  • tachycardia
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • drug-induced liver injury
  • agitation
  • depressed level of consciousness
  • hypokalaemia
  • hypoxia
10-19:
  • acute respiratory distress syndrome
  • blood bilirubin increased
  • hypernatraemia
  • hypotension
  • pneumonia respiratory syncytial viral
  • pneumonitis
  • somnolence
  • asthenia
  • dysarthria
  • abdominal pain
20-29:
  • nausea
  • headache
  • pain in extremity
  • diabetic ketoacidosis
  • drug withdrawal syndrome
  • gastroenteritis
  • joint swelling
  • oedema peripheral
  • upper respiratory tract infection
  • weight decreased
30-39:
  • pain
  • crohn's disease
  • vomiting
  • chest pain
  • anal abscess
  • anal fistula
  • fatigue
  • headache
  • pulmonary embolism
  • confusional state
40-49:
  • nausea
  • dyspnoea
  • pain
  • pneumonia
  • fatigue
  • osteomyelitis
  • anxiety
  • osteonecrosis of jaw
  • general physical health deterioration
  • constipation
50-59:
  • pain
  • joint dislocation
  • diarrhoea
  • abdominal pain
  • dysphagia
  • pleural effusion
  • nausea
  • cellulitis
  • osteoarthritis
  • lung disorder
60+:
  • pain
  • nausea
  • arthralgia
  • constipation
  • anxiety
  • oedema peripheral
  • bone disorder
  • fatigue
  • pyrexia
  • emotional distress

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Dilaudid (hydromorphone hydrochloride) is often used to treat pain. Methotrexate sodium (methotrexate sodium) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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