Review: taking Diphenhydramine hydrochloride and Aspirin together


Summary

Drug interactions are reported among people who take Diphenhydramine hydrochloride and Aspirin together. This review analyzes the effectiveness and drug interactions between Diphenhydramine hydrochloride and Aspirin. It is created by eHealthMe based on reports of 5,842 people who take the same drugs from FDA and social media, and is updated regularly.

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Diphenhydramine Hydrochloride

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. (latest outcomes from Diphenhydramine hydrochloride 4,549 users)

Aspirin

Aspirin has active ingredients of aspirin. It is often used in preventive health care. (latest outcomes from Aspirin 272,197 users)

On Sep, 16, 2016

5,842 people who take Diphenhydramine Hydrochloride, Aspirin are studied.


Number of reports submitted per year:

Diphenhydramine hydrochloride and Aspirin drug interactions.

Drug effectiveness over time:

Diphenhydramine Hydrochloride:
  • < 1 month: 12.0% - (2 of 16 people)
  • 1 - 6 months: 0.0% - (0 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 44.0% - (4 of 9 people)
  • 2 - 5 years: 37.0% - (3 of 8 people)
  • 5 - 10 years: 44.0% - (4 of 9 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Aspirin:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 12.0% - (1 of 8 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 0.0% - (0 of 5 people)
  • 2 - 5 years: 46.0% - (6 of 13 people)
  • 5 - 10 years: 33.0% - (2 of 6 people)
  • 10+ years: 75.0% - (3 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Diphenhydramine Hydrochloride:
  • female: 28.0% - (6 of 21 people)
  • male: 29.0% - (10 of 34 people)
Aspirin:
  • female: 33.0% - (5 of 15 people)
  • male: 32.0% - (10 of 31 people)

Drug effectiveness by age:

Diphenhydramine Hydrochloride:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 25.0% - (3 of 12 people)
  • 50-59: 30.0% - (4 of 13 people)
  • 60+: 35.0% - (6 of 17 people)
Aspirin:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 40.0% - (4 of 10 people)
  • 50-59: 54.0% - (6 of 11 people)
  • 60+: 20.0% - (3 of 15 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • renal failure
  • anxiety
  • injury
  • fear
  • multi-organ failure
  • pneumonia
  • death
  • nausea
  • vomiting
1 - 6 months:
  • neuropathy peripheral
  • depression
  • pleural effusion
  • anaemia
  • anxiety
  • arthralgia
  • bronchitis
  • epistaxis
  • nausea
  • pneumonia
6 - 12 months:
  • abnormal dreams
  • urinary tract infection
  • abdominal pain
  • adrenal insufficiency
  • anxiety
  • confusional state
  • constipation
  • dizziness postural
  • dry mouth
  • dysuria
1 - 2 years:
  • cerebral haemorrhage
  • convulsion
  • heart pounding or racing
  • hyponatraemia
  • migraine
  • multiple injuries
  • palpitations
  • syncope
  • cardiac arrest
  • haemorrhage
2 - 5 years:
  • death
  • sinusitis
  • convulsion
  • haemorrhage
  • heart pounding or racing
  • palpitations
  • arthralgia
  • cardiac arrest
  • fall
  • nephrogenic systemic fibrosis
5 - 10 years:
  • anger
  • pain exacerbated
  • stress
  • febrile neutropenia
  • hyponatraemia
  • insomnia
  • pneumonia
  • agitation
  • chills
  • epistaxis
10+ years:
  • feeling jittery
  • depression
  • restlessness aggravated
  • vision blurred
  • abdominal discomfort
  • abdominal pain
  • abdominal pain upper
  • arthralgia
  • asthenia
  • blood pressure fluctuation
not specified:
  • pain
  • nausea
  • fatigue
  • dyspnoea
  • anxiety
  • diarrhoea
  • vomiting
  • headache
  • arthralgia
  • dizziness

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • fatigue
  • anxiety
  • dyspnoea
  • headache
  • diarrhoea
  • vomiting
  • arthralgia
  • fall
male:
  • dyspnoea
  • pain
  • fatigue
  • nausea
  • anxiety
  • pneumonia
  • diarrhoea
  • dizziness
  • vomiting
  • asthenia

Most common drug interactions by age *:

0-1:
  • cerebral vasoconstriction
  • hypertension
  • haemolytic anaemia
  • tachycardia
  • hypotension
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • bronchial hyperreactivity
  • candidiasis
  • central line infection
2-9:
  • hepatitis c
  • fatigue
  • hepatitis c antibody positive
  • infectious mononucleosis
  • lethargy
  • liver function tests nos abnormal
  • abnormal behaviour
  • headache
  • hypertension
  • migraine
10-19:
  • pyrexia
  • chills
  • vomiting
  • nausea
  • pain
  • dizziness
  • multiple drug overdose intentional
  • suicide attempt
  • somnolence
  • gastric haemorrhage
20-29:
  • headache
  • dyspnoea
  • nausea
  • pain
  • vomiting
  • abdominal pain upper
  • cardiac failure congestive
  • anxiety
  • back pain
  • bronchitis
30-39:
  • pain
  • vomiting
  • headache
  • nausea
  • fatigue
  • weight increased
  • chest pain
  • completed suicide
  • arthralgia
  • anaemia
40-49:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • vomiting
  • emotional distress
  • dizziness
  • fatigue
  • diarrhoea
  • injury
50-59:
  • pain
  • nausea
  • anxiety
  • fatigue
  • headache
  • arthralgia
  • depression
  • dyspnoea
  • fall
  • hypotension
60+:
  • dyspnoea
  • fatigue
  • pain
  • nausea
  • diarrhoea
  • asthenia
  • pneumonia
  • anxiety
  • anaemia
  • fall

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Diphenhydramine hydrochloride (diphenhydramine hydrochloride) is often used to treat insomnia. Aspirin (aspirin) is often used to treat preventive health care. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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