Review: taking Diphenhydramine hydrochloride and Aspirin together


Summary

Drug interactions are reported among people who take Diphenhydramine hydrochloride and Aspirin together. This review analyzes the effectiveness and drug interactions between Diphenhydramine hydrochloride and Aspirin. It is created by eHealthMe based on reports of 3,607 people who take the same drugs from FDA and social media, and is updated regularly.

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Diphenhydramine Hydrochloride

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. (latest outcomes from Diphenhydramine hydrochloride 3,172 users)

Aspirin

Aspirin has active ingredients of aspirin. It is often used in preventive health care. (latest outcomes from Aspirin 184,887 users)

On Aug, 21, 2016

3,607 people who take Diphenhydramine Hydrochloride, Aspirin are studied.


Number of reports submitted per year:

Diphenhydramine hydrochloride and Aspirin drug interactions.

Drug effectiveness over time:

Diphenhydramine Hydrochloride:
  • < 1 month: 12.0% - (2 of 16 people)
  • 1 - 6 months: 0.0% - (0 of 5 people)
  • 6 - 12 months: 0.0% - (0 of 3 people)
  • 1 - 2 years: 44.0% - (4 of 9 people)
  • 2 - 5 years: 37.0% - (3 of 8 people)
  • 5 - 10 years: 44.0% - (4 of 9 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 0 people)
Aspirin:
  • < 1 month: 16.0% - (1 of 6 people)
  • 1 - 6 months: 12.0% - (1 of 8 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 0.0% - (0 of 5 people)
  • 2 - 5 years: 46.0% - (6 of 13 people)
  • 5 - 10 years: 33.0% - (2 of 6 people)
  • 10+ years: 75.0% - (3 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Diphenhydramine Hydrochloride:
  • female: 28.0% - (6 of 21 people)
  • male: 29.0% - (10 of 34 people)
Aspirin:
  • female: 33.0% - (5 of 15 people)
  • male: 32.0% - (10 of 31 people)

Drug effectiveness by age:

Diphenhydramine Hydrochloride:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 25.0% - (3 of 12 people)
  • 50-59: 30.0% - (4 of 13 people)
  • 60+: 35.0% - (6 of 17 people)
Aspirin:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 16.0% - (1 of 6 people)
  • 40-49: 40.0% - (4 of 10 people)
  • 50-59: 54.0% - (6 of 11 people)
  • 60+: 20.0% - (3 of 15 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • renal failure
  • anxiety
  • injury
  • fear
  • renal injury
  • anhedonia
  • multi-organ failure
  • emotional distress
  • stress
1 - 6 months:
  • depression
  • neuropathy peripheral
  • arthralgia
  • pleural effusion
  • antepartum haemorrhage
  • bronchitis
  • fall
  • feeling jittery
  • nausea
  • premature separation of placenta
6 - 12 months:
  • abdominal pain
  • abnormal dreams
  • adrenal insufficiency
  • anxiety
  • confusional state
  • constipation
  • dizziness postural
  • dry mouth
  • dysuria
  • excoriation
1 - 2 years:
  • convulsion
  • heart pounding or racing
  • hyponatraemia
  • palpitations
  • syncope
  • cardiac arrest
  • haemorrhage
  • aspartate aminotransferase increased
  • blood potassium increased
  • c-reactive protein increased
2 - 5 years:
  • death
  • sinusitis
  • convulsion
  • heart pounding or racing
  • palpitations
  • cardiac arrest
  • haemorrhage
  • nephrogenic systemic fibrosis
  • blood pressure increased
  • drowsiness
5 - 10 years:
  • anger
  • pain exacerbated
  • stress
  • febrile neutropenia
  • hyponatraemia
  • insomnia
  • pneumonia
  • chills
  • itching
  • benign positional vertigo
10+ years:
  • feeling jittery
  • depression
  • restlessness aggravated
  • dizziness aggravated
  • night sweats
  • pruritus aggravated
  • restless leg syndrome
  • weight above normal
  • hematospermia
  • lethargy
not specified:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • fatigue
  • diarrhoea
  • vomiting
  • anaemia
  • headache
  • dizziness

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • fatigue
  • diarrhoea
  • vomiting
  • fall
  • anaemia
  • headache
male:
  • dyspnoea
  • pain
  • anxiety
  • fatigue
  • nausea
  • injury
  • dizziness
  • pneumonia
  • asthenia
  • depression

Most common drug interactions by age *:

0-1:
  • cerebral vasoconstriction
  • hypertension
  • hypotension
  • tachycardia
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • bronchial hyperreactivity
  • candidiasis
  • central line infection
  • contrast media allergy
2-9:
  • hepatitis c
  • fatigue
  • hepatitis c antibody positive
  • infectious mononucleosis
  • lethargy
  • liver function tests nos abnormal
10-19:
  • chills
  • pyrexia
  • vomiting
  • nausea
  • dizziness
  • multiple drug overdose intentional
  • suicide attempt
  • pain
  • somnolence
  • headache
20-29:
  • nausea
  • dyspnoea
  • vomiting
  • headache
  • abdominal pain upper
  • convulsion
  • insomnia
  • pain
  • cardiac failure congestive
  • anxiety
30-39:
  • pain
  • weight increased
  • completed suicide
  • vomiting
  • nausea
  • anaemia
  • arthralgia
  • fatigue
  • headache
  • neck pain
40-49:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • emotional distress
  • injury
  • vomiting
  • depression
  • cardiac failure congestive
  • diarrhoea
50-59:
  • pain
  • anxiety
  • nausea
  • injury
  • headache
  • depression
  • fatigue
  • fall
  • diarrhoea
  • dyspnoea
60+:
  • pain
  • dyspnoea
  • anxiety
  • diarrhoea
  • fatigue
  • nausea
  • anaemia
  • asthenia
  • fall
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Diphenhydramine hydrochloride (diphenhydramine hydrochloride) is often used to treat insomnia. Aspirin (aspirin) is often used to treat preventive health care. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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