Review: taking Diphenhydramine hydrochloride and Aspirin together


Summary

Drug interactions are reported among people who take Diphenhydramine hydrochloride and Aspirin together. This review analyzes the effectiveness and drug interactions between Diphenhydramine hydrochloride and Aspirin. It is created by eHealthMe based on reports of 2,603 people who take the same drugs from FDA and social media, and is updated regularly.

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Diphenhydramine Hydrochloride

Diphenhydramine hydrochloride has active ingredients of diphenhydramine hydrochloride. It is often used in insomnia. (latest outcomes from Diphenhydramine hydrochloride 2,651 users)

Aspirin

Aspirin has active ingredients of aspirin. It is often used in preventive health care. (latest outcomes from Aspirin 160,694 users)

On Jul, 22, 2016

2,603 people who take Diphenhydramine Hydrochloride, Aspirin are studied.


Number of reports submitted per year:

Diphenhydramine hydrochloride and Aspirin drug interactions.

Drug effectiveness over time:

Diphenhydramine Hydrochloride:
  • < 1 month: 11.0% - (2 of 17 people)
  • 1 - 6 months: 0.0% - (0 of 10 people)
  • 6 - 12 months: 0.0% - (0 of 4 people)
  • 1 - 2 years: 33.0% - (4 of 12 people)
  • 2 - 5 years: 50.0% - (6 of 12 people)
  • 5 - 10 years: 33.0% - (4 of 12 people)
  • 10+ years: 37.0% - (3 of 8 people)
  • not specified: 0.0% - (0 of 0 people)
Aspirin:
  • < 1 month: 14.0% - (1 of 7 people)
  • 1 - 6 months: 11.0% - (1 of 9 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 0.0% - (0 of 8 people)
  • 2 - 5 years: 53.0% - (8 of 15 people)
  • 5 - 10 years: 22.0% - (2 of 9 people)
  • 10+ years: 80.0% - (4 of 5 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Diphenhydramine Hydrochloride:
  • female: 27.0% - (9 of 33 people)
  • male: 23.0% - (10 of 42 people)
Aspirin:
  • female: 30.0% - (6 of 20 people)
  • male: 32.0% - (12 of 37 people)

Drug effectiveness by age:

Diphenhydramine Hydrochloride:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 25.0% - (1 of 4 people)
  • 30-39: 12.0% - (1 of 8 people)
  • 40-49: 14.0% - (3 of 21 people)
  • 50-59: 23.0% - (4 of 17 people)
  • 60+: 37.0% - (9 of 24 people)
Aspirin:
  • 0-1: 100.0% - (1 of 1 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 3 people)
  • 30-39: 14.0% - (1 of 7 people)
  • 40-49: 50.0% - (7 of 14 people)
  • 50-59: 42.0% - (6 of 14 people)
  • 60+: 16.0% - (3 of 18 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • renal failure
  • injury
  • anxiety
  • fear
  • anhedonia
  • renal injury
  • multi-organ failure
  • emotional distress
  • death
1 - 6 months:
  • depression
  • neuropathy peripheral
  • pleural effusion
  • antepartum haemorrhage
  • arthralgia
  • bronchitis
  • fall
  • feeling jittery
  • premature separation of placenta
  • renal failure acute
6 - 12 months:
  • abdominal pain
  • abnormal dreams
  • adrenal insufficiency
  • anxiety
  • confusional state
  • constipation
  • dizziness postural
  • dry mouth
  • dysuria
  • excoriation
1 - 2 years:
  • convulsion
  • heart pounding or racing
  • hyponatraemia
  • palpitations
  • syncope
  • cardiac arrest
  • haemorrhage
  • aspartate aminotransferase increased
  • blood potassium increased
  • c-reactive protein increased
2 - 5 years:
  • death
  • convulsion
  • heart pounding or racing
  • palpitations
  • cardiac arrest
  • haemorrhage
  • sinusitis
  • blood pressure increased
  • drowsiness
  • hair loss
5 - 10 years:
  • anger
  • pain exacerbated
  • stress
  • febrile neutropenia
  • hyponatraemia
  • insomnia
  • pneumonia
  • chills
  • itching
  • benign positional vertigo
10+ years:
  • feeling jittery
  • depression
  • restlessness aggravated
  • dizziness aggravated
  • night sweats
  • pruritus aggravated
  • restless leg syndrome
  • weight above normal
  • hematospermia
  • lethargy
not specified:
  • pain
  • anxiety
  • dyspnoea
  • nausea
  • fatigue
  • vomiting
  • injury
  • diarrhoea
  • anaemia
  • dizziness

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • dyspnoea
  • vomiting
  • fatigue
  • diarrhoea
  • anaemia
  • fall
  • injury
male:
  • dyspnoea
  • pain
  • anxiety
  • injury
  • fatigue
  • renal failure
  • dizziness
  • depression
  • pneumonia
  • nausea

Most common drug interactions by age *:

0-1:
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • bronchial hyperreactivity
  • candidiasis
  • central line infection
  • eosinophilia
  • hypotension
  • orthostatic hypotension
  • renal failure acute
  • respiratory syncytial virus infection
2-9:
  • hepatitis c
  • fatigue
  • hepatitis c antibody positive
  • infectious mononucleosis
  • lethargy
  • liver function tests nos abnormal
10-19:
  • pyrexia
  • multiple drug overdose intentional
  • dizziness
  • somnolence
  • suicide attempt
  • vomiting
  • chills
  • pain
  • blood potassium decreased
  • catheter related infection
20-29:
  • nausea
  • vomiting
  • abdominal pain upper
  • headache
  • convulsion
  • dyspnoea
  • pericardial effusion
  • bronchitis
  • insomnia
  • presyncope
30-39:
  • pain
  • completed suicide
  • weight increased
  • neck pain
  • vomiting
  • anxiety
  • arthralgia
  • anaemia
  • nausea
  • biopsy breast abnormal
40-49:
  • anxiety
  • pain
  • emotional distress
  • dyspnoea
  • injury
  • nausea
  • depression
  • cardiac failure congestive
  • vomiting
  • chest pain
50-59:
  • anxiety
  • pain
  • nausea
  • injury
  • depression
  • headache
  • dyspnoea
  • vomiting
  • anaemia
  • renal failure acute
60+:
  • pain
  • dyspnoea
  • anxiety
  • fatigue
  • nausea
  • diarrhoea
  • asthenia
  • anaemia
  • renal failure
  • hypotension

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Diphenhydramine hydrochloride (diphenhydramine hydrochloride) is often used to treat insomnia. Aspirin (aspirin) is often used to treat preventive health care. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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