Review: taking Doxepin hydrochloride and Simvastatin together


Summary

Drug interactions are reported among people who take Doxepin hydrochloride and Simvastatin together. This review analyzes the effectiveness and drug interactions between Doxepin hydrochloride and Simvastatin. It is created by eHealthMe based on reports of 559 people who take the same drugs from FDA and social media, and is updated regularly.

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Doxepin Hydrochloride

Doxepin hydrochloride has active ingredients of doxepin hydrochloride. It is often used in depression. (latest outcomes from Doxepin hydrochloride 883 users)

Simvastatin

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 131,417 users)

On Sep, 05, 2016

559 people who take Doxepin Hydrochloride, Simvastatin are studied.


Number of reports submitted per year:

Doxepin hydrochloride and Simvastatin drug interactions.

Drug effectiveness over time:

Doxepin Hydrochloride:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Simvastatin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 4 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Doxepin Hydrochloride:
  • female: 40.0% - (2 of 5 people)
  • male: 33.0% - (2 of 6 people)
Simvastatin:
  • female: 0.0% - (0 of 5 people)
  • male: 50.0% - (3 of 6 people)

Drug effectiveness by age:

Doxepin Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 20.0% - (1 of 5 people)
Simvastatin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • constipation
  • electrocardiogram qt prolonged
  • multiple drug overdose intentional
  • myopathy
  • somnolence
  • asthenia
  • chronic inflammatory demyelinating polyradiculoneuropathy
  • drug dependence
  • dysstasia
  • gait disturbance
1 - 6 months:
  • anxiety
  • cholelithiasis
  • emotional distress
  • general physical health deterioration
  • hepatobiliary scan abnormal
  • pain
  • colitis collagenous
  • cholecystitis chronic
  • idiopathic thrombocytopenic purpura
  • abdominal pain
6 - 12 months:
  • rhabdomyolysis
  • influenza
  • ascites
  • biliary tract disorder
  • cholangitis sclerosing
  • drug-induced liver injury
  • hepatic enzyme abnormal
  • hepatitis cholestatic
  • myocardial infarction
  • pharyngolaryngeal pain
1 - 2 years:
  • ascites
  • balance disorder
  • biliary tract disorder
  • cholangitis sclerosing
  • drug-induced liver injury
  • hepatic enzyme abnormal
  • hepatitis cholestatic
  • pseudoporphyria
  • renal failure
  • syncope
2 - 5 years:
  • constipation
  • arrhythmia
  • arteriosclerosis coronary artery
  • cardio-respiratory arrest
  • dyspnoea
  • fatigue
  • hip fracture
  • muscular weakness
  • myocardial infarction
  • pain in extremity
5 - 10 years:
  • asthenia
  • fatigue
  • cerebrovascular accident
  • cholelithiasis
  • cholestasis
  • disorientation
  • dyspnoea
  • fall
  • splenomegaly
  • failure to thrive
10+ years:
  • breast cancer female
not specified:
  • nausea
  • depression
  • fall
  • dyspnoea
  • pain
  • chest pain
  • blood cholesterol increased
  • pain in extremity
  • anxiety
  • back pain

Most common drug interactions by gender *:

female:
  • dyspnoea
  • nausea
  • blood cholesterol increased
  • dizziness
  • type 2 diabetes mellitus
  • fall
  • headache
  • vomiting
  • pain in extremity
  • depression
male:
  • depression
  • nausea
  • fatigue
  • arthralgia
  • myalgia
  • vision blurred
  • back pain
  • chest pain
  • pain
  • weight decreased

Most common drug interactions by age *:

20-29:
  • anxiety
  • cholelithiasis
  • emotional distress
  • general physical health deterioration
  • hepatobiliary scan abnormal
  • pain
  • cholecystitis chronic
30-39:
  • depression
  • abdominal pain
  • back pain
  • nausea
  • pain
  • bone disorder
  • chronic obstructive pulmonary disease
  • dizziness
  • fall
  • osteoporosis
40-49:
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • hyperlipidaemia
  • headache
  • urinary tract infection
  • somnolence
  • dehydration
  • diabetes mellitus inadequate control
  • pancreatitis
  • diabetic retinopathy
50-59:
  • arthralgia
  • fatigue
  • gait disturbance
  • insomnia
  • nausea
  • type 2 diabetes mellitus
  • balance disorder
  • blood cholesterol increased
  • chest pain
  • completed suicide
60+:
  • nausea
  • dyspnoea
  • oedema peripheral
  • asthenia
  • fall
  • diarrhoea
  • fatigue
  • pain
  • pain in extremity
  • dizziness

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Doxepin hydrochloride (doxepin hydrochloride) is often used to treat depression. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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