Review: taking Doxepin hydrochloride and Simvastatin together


Summary

Drug interactions are reported among people who take Doxepin hydrochloride and Simvastatin together. This review analyzes the effectiveness and drug interactions between Doxepin hydrochloride and Simvastatin. It is created by eHealthMe based on reports of 494 people who take the same drugs from FDA and social media, and is updated regularly.

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Doxepin Hydrochloride

Doxepin hydrochloride has active ingredients of doxepin hydrochloride. It is often used in depression. (latest outcomes from Doxepin hydrochloride 782 users)

Simvastatin

Simvastatin has active ingredients of simvastatin. It is often used in high blood cholesterol. (latest outcomes from Simvastatin 94,390 users)

On Aug, 23, 2016

494 people who take Doxepin Hydrochloride, Simvastatin are studied.


Number of reports submitted per year:

Doxepin hydrochloride and Simvastatin drug interactions.

Drug effectiveness over time:

Doxepin Hydrochloride:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Simvastatin:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 4 people)
  • 2 - 5 years: 33.0% - (1 of 3 people)
  • 5 - 10 years: 0.0% - (0 of 2 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 100.0% - (1 of 1 people)

Drug effectiveness by gender:

Doxepin Hydrochloride:
  • female: 40.0% - (2 of 5 people)
  • male: 33.0% - (2 of 6 people)
Simvastatin:
  • female: 0.0% - (0 of 5 people)
  • male: 50.0% - (3 of 6 people)

Drug effectiveness by age:

Doxepin Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 100.0% - (1 of 1 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 20.0% - (1 of 5 people)
Simvastatin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 1 people)
  • 40-49: 66.0% - (2 of 3 people)
  • 50-59: 0.0% - (0 of 2 people)
  • 60+: 25.0% - (1 of 4 people)

Most common drug interactions over time *:

< 1 month:
  • constipation
  • multiple drug overdose intentional
  • myopathy
  • somnolence
  • asthenia
  • chronic inflammatory demyelinating polyradiculoneuropathy
  • drug dependence
  • dysstasia
  • gait disturbance
  • hallucination, visual
1 - 6 months:
  • anxiety
  • cholelithiasis
  • emotional distress
  • general physical health deterioration
  • hepatobiliary scan abnormal
  • pain
  • colitis collagenous
  • cholecystitis chronic
  • idiopathic thrombocytopenic purpura
  • abdominal pain
6 - 12 months:
  • rhabdomyolysis
  • influenza
  • ascites
  • biliary tract disorder
  • cholangitis sclerosing
  • drug-induced liver injury
  • hepatic enzyme abnormal
  • hepatitis cholestatic
  • myocardial infarction
  • pharyngolaryngeal pain
1 - 2 years:
  • ascites
  • balance disorder
  • biliary tract disorder
  • cholangitis sclerosing
  • drug-induced liver injury
  • hepatic enzyme abnormal
  • hepatitis cholestatic
  • pseudoporphyria
  • renal failure
  • syncope
2 - 5 years:
  • constipation
  • dyspnoea
  • fatigue
  • hip fracture
  • muscular weakness
  • pain in extremity
  • blood cholesterol increased
  • blood triglycerides increased
  • diabetic retinopathy
  • dizziness
5 - 10 years:
  • asthenia
  • fatigue
  • cerebrovascular accident
  • cholelithiasis
  • cholestasis
  • disorientation
  • dyspnoea
  • fall
  • splenomegaly
  • failure to thrive
10+ years:
  • breast cancer female
not specified:
  • nausea
  • depression
  • fall
  • blood cholesterol increased
  • pain in extremity
  • dyspnoea
  • pain
  • chest pain
  • anxiety
  • back pain

Most common drug interactions by gender *:

female:
  • dyspnoea
  • nausea
  • blood cholesterol increased
  • type 2 diabetes mellitus
  • dizziness
  • headache
  • pain in extremity
  • fall
  • vomiting
  • hyperlipidaemia
male:
  • nausea
  • depression
  • fatigue
  • arthralgia
  • myalgia
  • vision blurred
  • chest pain
  • pain
  • weight decreased
  • asthenia

Most common drug interactions by age *:

20-29:
  • anxiety
  • cholelithiasis
  • emotional distress
  • general physical health deterioration
  • hepatobiliary scan abnormal
  • pain
  • cholecystitis chronic
30-39:
  • depression
  • abdominal pain
  • anxiety
  • back pain
  • bronchitis
  • chest pain
  • decreased appetite
  • dehydration
  • dyspnoea
  • headache
40-49:
  • type 2 diabetes mellitus
  • blood cholesterol increased
  • hyperlipidaemia
  • headache
  • urinary tract infection
  • somnolence
  • dehydration
  • diabetes mellitus inadequate control
  • pancreatitis
  • diabetic retinopathy
50-59:
  • fatigue
  • insomnia
  • nausea
  • type 2 diabetes mellitus
  • arthralgia
  • blood cholesterol increased
  • confusional state
  • dyspnoea
  • muscle spasms
  • pain in extremity
60+:
  • nausea
  • oedema peripheral
  • dyspnoea
  • asthenia
  • fall
  • pain in extremity
  • dizziness
  • fatigue
  • pain
  • diarrhoea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Doxepin hydrochloride (doxepin hydrochloride) is often used to treat depression. Simvastatin (simvastatin) is often used to treat high blood cholesterol. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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