Review: taking Doxepin hydrochloride and Synthroid together


Summary

Drug interactions are reported among people who take Doxepin hydrochloride and Synthroid together. This review analyzes the effectiveness and drug interactions between Doxepin hydrochloride and Synthroid. It is created by eHealthMe based on reports of 789 people who take the same drugs from FDA and social media, and is updated regularly.

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Doxepin Hydrochloride

Doxepin hydrochloride has active ingredients of doxepin hydrochloride. It is often used in depression. (latest outcomes from Doxepin hydrochloride 708 users)

Synthroid

Synthroid has active ingredients of levothyroxine sodium. It is often used in hypothyroidism. (latest outcomes from Synthroid 92,449 users)

On Jul, 21, 2016

789 people who take Doxepin Hydrochloride, Synthroid are studied.


Number of reports submitted per year:

Doxepin hydrochloride and Synthroid drug interactions.

Drug effectiveness over time:

Doxepin Hydrochloride:
  • < 1 month: 33.0% - (1 of 3 people)
  • 1 - 6 months: 55.0% - (5 of 9 people)
  • 6 - 12 months: 100.0% - (2 of 2 people)
  • 1 - 2 years: 20.0% - (1 of 5 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (6 of 6 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 0.0% - (0 of 0 people)
Synthroid:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 50.0% - (2 of 4 people)
  • 2 - 5 years: 62.0% - (5 of 8 people)
  • 5 - 10 years: 60.0% - (3 of 5 people)
  • 10+ years: 75.0% - (9 of 12 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Doxepin Hydrochloride:
  • female: 59.0% - (16 of 27 people)
  • male: 66.0% - (6 of 9 people)
Synthroid:
  • female: 60.0% - (18 of 30 people)
  • male: 57.0% - (4 of 7 people)

Drug effectiveness by age:

Doxepin Hydrochloride:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 66.0% - (6 of 9 people)
  • 50-59: 33.0% - (2 of 6 people)
  • 60+: 70.0% - (12 of 17 people)
Synthroid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 60.0% - (3 of 5 people)
  • 40-49: 66.0% - (6 of 9 people)
  • 50-59: 71.0% - (5 of 7 people)
  • 60+: 46.0% - (7 of 15 people)

Most common drug interactions over time *:

< 1 month:
  • amnesia
  • convulsion
  • fatigue
  • malaise
  • oedema peripheral
  • somnolence
  • adverse reaction
  • aptyalism
  • aspartate aminotransferase increased
  • blood creatine phosphokinase increased
1 - 6 months:
  • anxiety disorder due to a general medical condition
  • fibromyalgia
  • hemochromatosis
  • high blood pressure
  • liver cirrhosis
  • low platelet count
  • cardiac failure
  • chronic obstructive pulmonary disease
  • dry eyes
  • high blood sugar
6 - 12 months:
  • affective disorder
  • amnesia
  • aura
  • bipolar ii disorder
  • confusional state
  • convulsion
  • fall
  • fatigue
  • loss of consciousness
  • memory impairment
1 - 2 years:
  • arthritis
  • dysarthria
  • intervertebral disc protrusion
  • lichen planus
  • limb discomfort
  • memory impairment
  • nervous system disorder
  • somnolence
  • accidental death
  • body height decreased
2 - 5 years:
  • anxiety disorder due to a general medical condition
  • dry mouth
  • fatigue
  • fibromyalgia
  • hemochromatosis
  • high blood pressure
  • liver cirrhosis
  • low platelet count
  • abnormal behaviour
  • aggression
5 - 10 years:
  • completed suicide
  • constipation aggravated
  • dry eyes
  • high blood sugar
  • lethargy
  • accidental death
  • agitated depression
  • anticipatory anxiety
  • cognitive deterioration
  • coma
10+ years:
  • dry mouth
  • fatigue
  • fatigue aggravated
  • death
  • shortness of breath
not specified:
  • nausea
  • anxiety
  • pain in extremity
  • back pain
  • chest pain
  • pain
  • fall
  • fatigue
  • osteonecrosis of jaw
  • vomiting

Most common drug interactions by gender *:

female:
  • nausea
  • fatigue
  • pain in extremity
  • anxiety
  • back pain
  • chest pain
  • diarrhoea
  • pain
  • vomiting
  • fall
male:
  • oedema peripheral
  • pyrexia
  • arthralgia
  • drug ineffective
  • cerebrovascular accident
  • fatigue
  • dyspnoea
  • anxiety
  • cardiac failure congestive
  • contusion

Most common drug interactions by age *:

20-29:
  • hepatic failure
  • suicide attempt
  • abdominal pain
  • aggression
  • computerised tomogram abnormal
  • difficulty in micturition
  • drug dependence
  • drug ineffective
  • drug toxicity
  • dry mouth
30-39:
  • nausea
  • depression
  • bipolar disorder
  • fatigue
  • blood glucose increased
  • hypothyroidism
  • paraesthesia
  • anxiety
  • injection site haematoma
  • injection site pain
40-49:
  • nausea
  • chest pain
  • vomiting
  • bronchitis
  • hypothyroidism
  • abdominal pain upper
  • hiatus hernia
  • pyrexia
  • amnesia
  • blood cholesterol increased
50-59:
  • nausea
  • pain in extremity
  • headache
  • back pain
  • chest pain
  • osteoarthritis
  • osteopenia
  • atelectasis
  • anxiety
  • arthralgia
60+:
  • fatigue
  • diarrhoea
  • dizziness
  • nausea
  • anxiety
  • pyrexia
  • dyspnoea
  • pain
  • back pain
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Doxepin hydrochloride (doxepin hydrochloride) is often used to treat depression. Synthroid (levothyroxine sodium) is often used to treat hypothyroidism. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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