Review: taking Doxycycline hyclate and Hydroxyzine together


Summary

Drug interactions are reported among people who take Doxycycline hyclate and Hydroxyzine together. This review analyzes the effectiveness and drug interactions between Doxycycline hyclate and Hydroxyzine. It is created by eHealthMe based on reports of 265 people who take the same drugs from FDA and social media, and is updated regularly.

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Doxycycline Hyclate

Doxycycline hyclate has active ingredients of doxycycline hyclate. It is often used in acne. (latest outcomes from Doxycycline hyclate 2,887 users)

Hydroxyzine

Hydroxyzine has active ingredients of hydroxyzine hydrochloride. It is often used in itching. (latest outcomes from Hydroxyzine 9,779 users)

On Aug, 26, 2016

265 people who take Doxycycline Hyclate, Hydroxyzine are studied.


Number of reports submitted per year:

Doxycycline hyclate and Hydroxyzine drug interactions.

Drug effectiveness over time:

Doxycycline Hyclate:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)
Hydroxyzine:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 3 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Doxycycline Hyclate:
  • female: 50.0% - (2 of 4 people)
  • male: 0.0% - (0 of 1 people)
Hydroxyzine:
  • female: 0.0% - (0 of 4 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Doxycycline Hyclate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 100.0% - (1 of 1 people)
  • 30-39: 33.0% - (1 of 3 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)
Hydroxyzine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 0.0% - (0 of 3 people)
  • 40-49: 0.0% - (0 of 1 people)
  • 50-59: 0.0% - (0 of 0 people)
  • 60+: 0.0% - (0 of 0 people)

Most common drug interactions over time *:

< 1 month:
  • toxic epidermal necrolysis
  • dizziness
  • depressed mood
  • drug ineffective
  • dyspnoea
  • hypersensitivity
  • hypoxia
  • insomnia
  • loss of appetite
  • oedema
1 - 6 months:
  • toxic epidermal necrolysis
  • death
  • bladder pain
  • cardiac arrest
  • cytolytic hepatitis
  • febrile bone marrow aplasia
  • muscle spasms
  • neuropathy peripheral
  • vulvovaginal burning sensation
6 - 12 months:
  • death
  • cardiac arrest
1 - 2 years:
  • acne
  • bladder pain
  • petechiae
  • vulvovaginal burning sensation
  • weight gain - unintentional
2 - 5 years:
  • abdominal pain
  • acute sinusitis
  • alopecia
  • anaemia
  • arthropathy
  • asthma
  • blood alkaline phosphatase increased
  • blood creatine phosphokinase abnormal
  • breast mass
  • bronchitis
5 - 10 years:
  • deep vein thrombosis
  • injury
  • pain
  • pulmonary embolism
  • anxiety
  • convulsion
  • discomfort
  • fractured coccyx
  • fractured sacrum
  • loss of consciousness
not specified:
  • fatigue
  • dizziness
  • asthenia
  • anxiety
  • rash
  • pain
  • nausea
  • skin lesion
  • vomiting
  • pyrexia

Most common drug interactions by gender *:

female:
  • fatigue
  • dizziness
  • asthenia
  • rash
  • myalgia
  • alopecia
  • hepatomegaly
  • rhinitis allergic
  • vaginal haemorrhage
  • hodgkin's disease
male:
  • anxiety
  • weight decreased
  • diarrhoea
  • pain
  • injury
  • depression
  • dyspnoea
  • nausea
  • vomiting
  • back pain

Most common drug interactions by age *:

20-29:
  • asthenia
  • vaginal haemorrhage
  • alopecia
  • hepatomegaly
  • hodgkin's disease
  • keloid scar
  • laryngocele
  • pneumothorax
  • dizziness
  • eczema
30-39:
  • weight decreased
  • anxiety
  • panic attack
  • gastritis
  • skin lesion
  • depression
  • nausea
  • dyspnoea
  • fatigue
  • vomiting
40-49:
  • pyrexia
  • depression
  • rheumatoid arthritis
  • anxiety
  • drug dependence
  • drug ineffective
  • drug withdrawal syndrome
  • dyspnoea
  • sickle cell anaemia with crisis
  • synovitis
50-59:
  • dizziness
  • nausea
  • pyrexia
  • gastrooesophageal reflux disease
  • neck pain
  • type 2 diabetes mellitus
  • chronic obstructive pulmonary disease
  • diabetes mellitus inadequate control
  • anxiety
  • renal failure chronic
60+:
  • dizziness
  • asthenia
  • pain
  • diarrhoea
  • dyspnoea
  • anxiety
  • rash
  • vomiting
  • fatigue
  • nausea

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Doxycycline hyclate (doxycycline hyclate) is often used to treat acne. Hydroxyzine (hydroxyzine hydrochloride) is often used to treat itching. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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