Review: taking Doxycycline and Folic acid together


Summary

Drug interactions are reported among people who take Doxycycline and Folic acid together. This review analyzes the effectiveness and drug interactions between Doxycycline and Folic acid. It is created by eHealthMe based on reports of 660 people who take the same drugs from FDA and social media, and is updated regularly.

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Doxycycline

Doxycycline has active ingredients of doxycycline hyclate. It is often used in acne. (latest outcomes from Doxycycline 15,796 users)

Folic Acid

Folic acid has active ingredients of folic acid. It is often used in vitamin supplementation. (latest outcomes from Folic acid 97,137 users)

On Aug, 22, 2016

660 people who take Doxycycline, Folic Acid are studied.


Number of reports submitted per year:

Doxycycline and Folic acid drug interactions.

Drug effectiveness over time:

Doxycycline:
  • < 1 month: 50.0% - (1 of 2 people)
  • 1 - 6 months: 50.0% - (1 of 2 people)
  • 6 - 12 months: 0.0% - (0 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 100.0% - (1 of 1 people)
  • 5 - 10 years: 100.0% - (2 of 2 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Folic Acid:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 2 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 66.0% - (2 of 3 people)
  • 5 - 10 years: 100.0% - (1 of 1 people)
  • 10+ years: 100.0% - (3 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Doxycycline:
  • female: 83.0% - (5 of 6 people)
  • male: 50.0% - (2 of 4 people)
Folic Acid:
  • female: 66.0% - (4 of 6 people)
  • male: 75.0% - (3 of 4 people)

Drug effectiveness by age:

Doxycycline:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 2 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 100.0% - (3 of 3 people)
  • 60+: 50.0% - (1 of 2 people)
Folic Acid:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 100.0% - (2 of 2 people)
  • 40-49: 100.0% - (1 of 1 people)
  • 50-59: 33.0% - (1 of 3 people)
  • 60+: 100.0% - (2 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • amnesia
  • dehydration
  • pain
  • diarrhoea
  • hepatic function abnormal
  • nausea
  • aggression
  • hyponatraemia
  • jaundice
  • renal failure
1 - 6 months:
  • abdominal pain
  • aortic valve incompetence
  • atrial fibrillation
  • chest pain
  • decreased appetite
  • diarrhoea
  • endocarditis
  • herpes oesophagitis
  • herpes virus infection
  • lethargy
6 - 12 months:
  • vitamin k
1 - 2 years:
  • anaemia
  • lower respiratory tract infection
2 - 5 years:
  • abdominal pain
  • acute sinusitis
  • alopecia
  • anaemia
  • arthropathy
  • asthma
  • blood alkaline phosphatase increased
  • blood creatine phosphokinase abnormal
  • breast mass
  • bronchitis
5 - 10 years:
  • colon cancer
  • injury
  • abdominal abscess
  • abdominal pain
  • adverse event
  • anxiety
  • conjunctivitis
  • deep vein thrombosis
  • emotional distress
  • general physical health deterioration
10+ years:
  • infected lymphocele
not specified:
  • pain
  • dyspnoea
  • nausea
  • anxiety
  • anaemia
  • chest pain
  • osteonecrosis of jaw
  • pain in jaw
  • pyrexia
  • diarrhoea

Most common drug interactions by gender *:

female:
  • nausea
  • pain
  • dyspnoea
  • diarrhoea
  • vomiting
  • abdominal pain
  • fall
  • pain in extremity
  • anxiety
  • pyrexia
male:
  • anaemia
  • anxiety
  • pain
  • dyspnoea
  • chest pain
  • osteonecrosis of jaw
  • bone disorder
  • pain in jaw
  • inflammation
  • purulent discharge

Most common drug interactions by age *:

0-1:
  • congenital osteodystrophy
  • emotional distress
  • meningomyelocele
  • neonatal tachypnoea
  • pyelocaliectasis
  • scoliosis
2-9:
  • arthralgia
  • diabetes mellitus
  • dry eye
  • erythema nodosum
  • eye infection
  • eye inflammation
  • eye irritation
  • eye pruritus
  • feeling abnormal
  • headache
10-19:
  • blister
  • corneal erosion
  • epidermal necrolysis
  • iritis
  • multi-organ failure
  • pyrexia
  • stevens johnson syndrome
  • abdominal pain
  • cholelithiasis
  • crohn's disease
20-29:
  • nausea
  • deep vein thrombosis
  • pain
  • abdominal pain
  • abdominal pain upper
  • biliary dyskinesia
  • cholecystitis chronic
  • vomiting
  • wegener's granulomatosis
  • diarrhoea
30-39:
  • palpitations
  • abortion spontaneous
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • blood bilirubin increased
  • blood sodium increased
  • bronchitis
  • deep vein thrombosis
  • gamma-glutamyltransferase increased
  • oedema lower limb
40-49:
  • anxiety
  • chest pain
  • pyrexia
  • pain
  • pseudomonas infection
  • rheumatoid arthritis
  • dehydration
  • depression
  • drug ineffective
  • dyspnoea
50-59:
  • nausea
  • diarrhoea
  • pain
  • anxiety
  • pyrexia
  • vomiting
  • injury
  • emotional distress
  • abdominal pain
  • fall
60+:
  • anaemia
  • dyspnoea
  • pain
  • nausea
  • pain in jaw
  • intervertebral disc degeneration
  • osteoarthritis
  • osteonecrosis of jaw
  • bone disorder
  • asthenia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Doxycycline (doxycycline hyclate) is often used to treat acne. Folic acid (folic acid) is often used to treat vitamin supplementation. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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