Review: taking Duloxetine and Gabapentin together


Summary

Drug interactions are reported among people who take Duloxetine and Gabapentin together. This review analyzes the effectiveness and drug interactions between Duloxetine and Gabapentin. It is created by eHealthMe based on reports of 4,776 people who take the same drugs from FDA and social media, and is updated regularly.

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Duloxetine

Duloxetine has active ingredients of duloxetine. It is often used in depression. (latest outcomes from Duloxetine 2,727 users)

Gabapentin

Gabapentin has active ingredients of gabapentin. It is often used in pain. (latest outcomes from Gabapentin 38,775 users)

On Jul, 19, 2016

4,776 people who take Duloxetine, Gabapentin are studied.


Number of reports submitted per year:

Duloxetine and Gabapentin drug interactions.

Drug effectiveness over time:

Duloxetine:
  • < 1 month: 9.0% - (4 of 42 people)
  • 1 - 6 months: 23.0% - (20 of 85 people)
  • 6 - 12 months: 31.0% - (18 of 58 people)
  • 1 - 2 years: 28.0% - (22 of 78 people)
  • 2 - 5 years: 38.0% - (41 of 106 people)
  • 5 - 10 years: 31.0% - (14 of 45 people)
  • 10+ years: 28.0% - (4 of 14 people)
  • not specified: 33.0% - (2 of 6 people)
Gabapentin:
  • < 1 month: 21.0% - (9 of 41 people)
  • 1 - 6 months: 23.0% - (15 of 65 people)
  • 6 - 12 months: 24.0% - (15 of 61 people)
  • 1 - 2 years: 22.0% - (19 of 86 people)
  • 2 - 5 years: 28.0% - (30 of 104 people)
  • 5 - 10 years: 26.0% - (16 of 61 people)
  • 10+ years: 33.0% - (7 of 21 people)
  • not specified: 20.0% - (1 of 5 people)

Drug effectiveness by gender:

Duloxetine:
  • female: 30.0% - (109 of 362 people)
  • male: 22.0% - (16 of 72 people)
Gabapentin:
  • female: 25.0% - (95 of 366 people)
  • male: 21.0% - (17 of 78 people)

Drug effectiveness by age:

Duloxetine:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 50.0% - (1 of 2 people)
  • 20-29: 18.0% - (6 of 32 people)
  • 30-39: 20.0% - (19 of 93 people)
  • 40-49: 33.0% - (41 of 123 people)
  • 50-59: 34.0% - (33 of 97 people)
  • 60+: 28.0% - (25 of 87 people)
Gabapentin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 1 people)
  • 20-29: 12.0% - (4 of 31 people)
  • 30-39: 23.0% - (23 of 98 people)
  • 40-49: 30.0% - (39 of 126 people)
  • 50-59: 24.0% - (24 of 97 people)
  • 60+: 24.0% - (22 of 91 people)

Most common drug interactions over time *:

< 1 month:
  • headache
  • nausea
  • dizziness
  • not breathing
  • pain - neck
  • abdominal pain upper
  • drug ineffective
  • somnolence
  • insomnia
  • pain
1 - 6 months:
  • dizziness
  • fall
  • drug ineffective
  • headache
  • pneumonia
  • abdominal pain
  • aspartate aminotransferase increased
  • loss of consciousness
  • alanine aminotransferase increased
  • convulsion
6 - 12 months:
  • anxiety
  • dizziness
  • drug ineffective
  • depression
  • pain
  • diarrhea
  • insomnia
  • nausea
  • tremor
  • disturbance in attention
1 - 2 years:
  • type 2 diabetes mellitus
  • fibromyalgia
  • nausea
  • tinnitus
  • erectile dysfunction
  • neuropathy peripheral
  • pain
  • anxiety
  • depression
  • disturbance in attention
2 - 5 years:
  • pain
  • depression
  • pancreatitis
  • sleep apnoea syndrome
  • tardive dyskinesia
  • suicidal ideation
  • convulsion
  • renal failure
  • road traffic accident
  • suicide attempt
5 - 10 years:
  • rash
  • open wound
  • swelling of the ankles - feet - legs
  • suicidal ideation
  • depression
  • diabetes mellitus
  • fatigue
  • high blood cholesterol
  • high blood sugar
  • sleep apnoea syndrome
10+ years:
  • swollen tongue
  • eczema eyelids
  • high blood cholesterol
  • high blood sugar
  • hyperkalaemia
  • swelling face
  • restless leg syndrome
  • anxiety
  • chf
  • deep vein thrombosis
not specified:
  • pain
  • nausea
  • fatigue
  • anxiety
  • depression
  • fall
  • headache
  • dizziness
  • pain in extremity
  • back pain

Most common drug interactions by gender *:

female:
  • pain
  • nausea
  • anxiety
  • fall
  • headache
  • fatigue
  • depression
  • dizziness
  • pain in extremity
  • insomnia
male:
  • pain
  • depression
  • fatigue
  • nausea
  • vomiting
  • anxiety
  • neuropathy peripheral
  • dizziness
  • anaemia
  • drug ineffective

Most common drug interactions by age *:

0-1:
  • blood cholesterol increased
  • gallbladder operation
  • sensation of foreign body
  • type 2 diabetes mellitus
  • agitation
  • diabetes mellitus inadequate control
  • ketoacidosis
  • pancreatitis acute
  • suicidal ideation
10-19:
  • pain
  • gallbladder disorder
  • suicidal ideation
  • cholecystitis chronic
  • pancreatitis
  • sphincter of oddi dysfunction
  • abdominal pain
  • alanine aminotransferase increased
  • aspartate aminotransferase increased
  • depression
20-29:
  • headache
  • vomiting
  • pain
  • insomnia
  • dyspnoea
  • nausea
  • suicidal ideation
  • dizziness
  • not breathing
  • pain - neck
30-39:
  • fatigue
  • headache
  • depression
  • dizziness
  • nausea
  • pain
  • cellulitis
  • type 2 diabetes mellitus
  • anxiety
  • paraesthesia
40-49:
  • pain
  • type 2 diabetes mellitus
  • nausea
  • neuropathy peripheral
  • headache
  • depression
  • anxiety
  • hypoaesthesia
  • chest pain
  • muscle spasms
50-59:
  • pain
  • nausea
  • anxiety
  • fall
  • dizziness
  • diarrhoea
  • arthralgia
  • depression
  • insomnia
  • pyrexia
60+:
  • pain
  • fall
  • nausea
  • fatigue
  • back pain
  • anxiety
  • anaemia
  • pain in extremity
  • dizziness
  • headache

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Duloxetine (duloxetine) is often used to treat depression. Gabapentin (gabapentin) is often used to treat pain. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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