Review: taking Effexor and Melatonin together


Summary

Drug interactions are reported among people who take Effexor and Melatonin together. This review analyzes the effectiveness and drug interactions between Effexor and Melatonin. It is created by eHealthMe based on reports of 112 people who take the same drugs from FDA and social media, and is updated regularly.

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Effexor

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. (latest outcomes from Effexor 54,461 users)

Melatonin

Melatonin has active ingredients of melatonin. It is often used in insomnia. (latest outcomes from Melatonin 3,072 users)

On Jul, 27, 2016

112 people who take Effexor, Melatonin are studied.


Number of reports submitted per year:

Effexor and Melatonin drug interactions.

Drug effectiveness over time:

Effexor:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 4 people)
  • 6 - 12 months: 50.0% - (2 of 4 people)
  • 1 - 2 years: 50.0% - (2 of 4 people)
  • 2 - 5 years: 100.0% - (3 of 3 people)
  • 5 - 10 years: 75.0% - (3 of 4 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 100.0% - (1 of 1 people)
Melatonin:
  • < 1 month: 0.0% - (0 of 3 people)
  • 1 - 6 months: 75.0% - (3 of 4 people)
  • 6 - 12 months: 100.0% - (1 of 1 people)
  • 1 - 2 years: 100.0% - (1 of 1 people)
  • 2 - 5 years: 75.0% - (3 of 4 people)
  • 5 - 10 years: 60.0% - (3 of 5 people)
  • 10+ years: 60.0% - (3 of 5 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Effexor:
  • female: 54.0% - (13 of 24 people)
  • male: 60.0% - (3 of 5 people)
Melatonin:
  • female: 47.0% - (9 of 19 people)
  • male: 100.0% - (5 of 5 people)

Drug effectiveness by age:

Effexor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 5 people)
  • 30-39: 85.0% - (6 of 7 people)
  • 40-49: 20.0% - (1 of 5 people)
  • 50-59: 66.0% - (4 of 6 people)
  • 60+: 83.0% - (5 of 6 people)
Melatonin:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (2 of 4 people)
  • 30-39: 60.0% - (3 of 5 people)
  • 40-49: 80.0% - (4 of 5 people)
  • 50-59: 50.0% - (2 of 4 people)
  • 60+: 50.0% - (3 of 6 people)

Most common drug interactions over time *:

< 1 month:
  • feeling abnormal
  • nausea
  • anger
  • dizziness
  • irritability
  • myalgia
  • suicidal ideation
  • suicide attempt
  • aggression
  • agitation
1 - 6 months:
  • nausea
  • suicidal ideation
  • suicide attempt
  • agitation
  • dizziness
  • loss of appetite
  • major depressive disorder
  • psychomotor hyperactivity
  • somnolence
  • aggression
6 - 12 months:
  • aggression
  • agitation
  • anger
  • belligerence
  • disinhibition
  • disturbance in social behaviour
  • eating disorder
  • euphoric mood
  • feeling abnormal
  • feeling jittery
1 - 2 years:
  • abnormal weight gain
  • appetite increased
  • bone pain
  • decreased activity
  • decreased interest
  • exercise tolerance decreased
  • fall
  • heat intolerance
  • increased tendency to bruise
  • livedo reticularis
2 - 5 years:
  • bone loss
  • drowsiness
  • dry mouth
  • fatigue
  • headache
  • heartburn - chronic
  • increased tendency to bruise
  • insomnia
  • itching
  • malaise
5 - 10 years:
  • anxiety
  • appetite increased
  • bone pain
  • cerebrovascular accident
  • cholecystitis chronic
  • decreased activity
  • decreased interest
  • deep vein thrombosis
  • abnormal weight gain
  • anhedonia
10+ years:
  • diarrhea
  • fatigue
  • memory impairment
  • noises or buzzing in the ears
  • weight increased
  • deja vu
  • drug withdrawal syndrome
  • tinnitus
not specified:
  • anxiety
  • depression
  • dyspnoea
  • fatigue
  • pain
  • back pain
  • chronic obstructive pulmonary disease
  • hot flush
  • mouth ulceration
  • arthralgia

Most common drug interactions by gender *:

female:
  • nausea
  • suicidal ideation
  • dizziness
  • weight increased
  • malaise
  • myalgia
  • agitation
  • feeling abnormal
  • sleep disorder
  • somnolence
male:
  • diarrhea
  • agitation
  • akathisia
  • anxiety
  • dependence
  • drug ineffective
  • fatigue
  • insomnia
  • psychomotor hyperactivity
  • restless legs syndrome

Most common drug interactions by age *:

10-19:
  • aggression
  • agitation
  • anger
  • belligerence
  • disinhibition
  • disturbance in social behaviour
  • eating disorder
  • euphoric mood
  • feeling abnormal
  • feeling jittery
20-29:
  • nausea
  • loss of appetite
  • major depressive disorder
  • diabetes mellitus
  • dizziness
  • gastrooesophageal reflux disease
  • lactic acidosis
  • malaise
  • mouth ulceration
  • abdominal pain
30-39:
  • altered state of consciousness
  • dizziness
  • ear discomfort
  • epistaxis
  • hallucination, auditory
  • hearing impaired
  • increased tendency to bruise
  • musculoskeletal chest pain
  • nausea
  • paraesthesia
40-49:
  • depression
  • anxiety
  • deep vein thrombosis
  • fatigue
  • influenza
  • mood altered
  • nasopharyngitis
  • pulmonary embolism
  • suicidal ideation
  • violence-related symptom
50-59:
  • insomnia
  • anxiety
  • fatigue
  • psychomotor hyperactivity
  • feeling abnormal
  • agitation
  • akathisia
  • dependence
  • drug ineffective
  • restless legs syndrome
60+:
  • arthralgia
  • weight increased
  • alopecia
  • anxiety
  • fatigue
  • insomnia
  • nausea
  • agitation
  • anorgasmia
  • confusional state

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Effexor (venlafaxine hydrochloride) is often used to treat depression. Melatonin (melatonin) is often used to treat insomnia. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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