Review: taking Effexor and Prozac together


Summary

Drug interactions are reported among people who take Effexor and Prozac together. This review analyzes the effectiveness and drug interactions between Effexor and Prozac. It is created by eHealthMe based on reports of 1,968 people who take the same drugs from FDA and social media, and is updated regularly.

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Effexor

Effexor has active ingredients of venlafaxine hydrochloride. It is often used in depression. (latest outcomes from Effexor 54,389 users)

Prozac

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. (latest outcomes from Prozac 41,873 users)

On Jul, 30, 2016

1,968 people who take Effexor, Prozac are studied.


Number of reports submitted per year:

Effexor and Prozac drug interactions.

Drug effectiveness over time:

Effexor:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 4.0% - (1 of 21 people)
  • 6 - 12 months: 0.0% - (0 of 7 people)
  • 1 - 2 years: 50.0% - (5 of 10 people)
  • 2 - 5 years: 30.0% - (4 of 13 people)
  • 5 - 10 years: 66.0% - (2 of 3 people)
  • 10+ years: 57.0% - (4 of 7 people)
  • not specified: 0.0% - (0 of 0 people)
Prozac:
  • < 1 month: 25.0% - (2 of 8 people)
  • 1 - 6 months: 8.0% - (2 of 23 people)
  • 6 - 12 months: 0.0% - (0 of 4 people)
  • 1 - 2 years: 50.0% - (3 of 6 people)
  • 2 - 5 years: 30.0% - (3 of 10 people)
  • 5 - 10 years: 50.0% - (1 of 2 people)
  • 10+ years: 45.0% - (5 of 11 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Effexor:
  • female: 23.0% - (12 of 51 people)
  • male: 33.0% - (4 of 12 people)
Prozac:
  • female: 19.0% - (10 of 52 people)
  • male: 50.0% - (6 of 12 people)

Drug effectiveness by age:

Effexor:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 22.0% - (2 of 9 people)
  • 30-39: 42.0% - (3 of 7 people)
  • 40-49: 15.0% - (3 of 20 people)
  • 50-59: 18.0% - (2 of 11 people)
  • 60+: 42.0% - (6 of 14 people)
Prozac:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 2 people)
  • 20-29: 33.0% - (3 of 9 people)
  • 30-39: 11.0% - (1 of 9 people)
  • 40-49: 15.0% - (3 of 19 people)
  • 50-59: 18.0% - (2 of 11 people)
  • 60+: 50.0% - (7 of 14 people)

Most common drug interactions over time *:

< 1 month:
  • muscle spasms
  • asthenia
  • weight decreased
  • apathy
  • dysphagia
  • coordination abnormal
  • dysarthria
  • fall
  • gait disturbance
  • aphasia
1 - 6 months:
  • aggression
  • drug withdrawal syndrome
  • depression
  • suicidal ideation
  • grand mal convulsion
  • type 2 diabetes mellitus
  • suicide attempt
  • obesity
  • pain
  • tremor
6 - 12 months:
  • suicidal ideation
  • suicide attempt
  • weight increased
  • feeling abnormal
  • malaise
  • somnolence
  • aggression
  • agitation
  • anger
  • belligerence
1 - 2 years:
  • anxiety
  • depression
  • diabetes mellitus
  • vertigo
  • arthropathy
  • cerebral cyst
  • oral herpes
  • osteonecrosis
  • temporomandibular joint syndrome
  • wound
2 - 5 years:
  • anxiety
  • type 2 diabetes mellitus
  • insomnia
  • chest pain
  • blood cholesterol increased
  • osteoporosis
  • blood triglycerides increased
  • paraesthesia
  • abdominal pain
  • back pain
5 - 10 years:
  • anxiety
  • vertigo
  • depression
  • arthropathy
  • cerebral cyst
  • oral herpes
  • osteonecrosis
  • temporomandibular joint syndrome
  • wound
  • aphthous stomatitis
10+ years:
  • diarrhea
  • loss of consciousness
  • serotonin syndrome
  • weight increased
  • abnormal behaviour
  • anxiety
  • back pain
  • chest pain
  • coronary artery disease
  • crying
not specified:
  • anxiety
  • pain
  • depression
  • suicidal ideation
  • back pain
  • nausea
  • fatigue
  • fall
  • headache
  • drug ineffective

Most common drug interactions by gender *:

female:
  • anxiety
  • pain
  • depression
  • nausea
  • fatigue
  • suicidal ideation
  • fall
  • dizziness
  • weight increased
  • headache
male:
  • anxiety
  • depression
  • suicidal ideation
  • pain
  • drug ineffective
  • weight decreased
  • fall
  • asthenia
  • back pain
  • drug withdrawal syndrome

Most common drug interactions by age *:

0-1:
  • bundle branch block right
  • chest pain
  • diabetes mellitus
  • type 2 diabetes mellitus
  • arterial disorder
  • bronchitis
  • cellulitis
  • diabetic ketoacidosis
  • fracture
  • infection
10-19:
  • aggression
  • suicidal ideation
  • suicide attempt
  • anger
  • somnolence
  • agitation
  • psychomotor hyperactivity
  • weight increased
  • impulse-control disorder
  • nausea
20-29:
  • suicidal ideation
  • drug withdrawal syndrome
  • depression
  • suicide attempt
  • anxiety
  • vision blurred
  • drug ineffective
  • headache
  • diabetes mellitus
  • nausea
30-39:
  • depression
  • suicidal ideation
  • anxiety
  • diabetes mellitus
  • nausea
  • suicide attempt
  • insomnia
  • dizziness
  • paraesthesia
  • drug withdrawal syndrome
40-49:
  • anxiety
  • diabetes mellitus
  • type 2 diabetes mellitus
  • depression
  • pain
  • fatigue
  • nausea
  • headache
  • back pain
  • drug withdrawal syndrome
50-59:
  • fall
  • anxiety
  • pain
  • depression
  • weight decreased
  • asthenia
  • drug ineffective
  • oedema peripheral
  • constipation
  • balance disorder
60+:
  • anxiety
  • pain
  • fall
  • osteonecrosis of jaw
  • diarrhoea
  • back pain
  • bone disorder
  • depression
  • vitreous floaters
  • fatigue

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Effexor (venlafaxine hydrochloride) is often used to treat depression. Prozac (fluoxetine hydrochloride) is often used to treat depression. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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