Review: taking Enbrel and Plaquenil together


Summary

Drug interactions are reported among people who take Enbrel and Plaquenil together. This review analyzes the effectiveness and drug interactions between Enbrel and Plaquenil. It is created by eHealthMe based on reports of 7,727 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone

Join a support group for people who take Enbrel and Plaquenil >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Enbrel

Enbrel has active ingredients of etanercept. It is often used in rheumatoid arthritis. (latest outcomes from Enbrel 172,634 users)

Plaquenil

Plaquenil has active ingredients of hydroxychloroquine sulfate. It is often used in rheumatoid arthritis. (latest outcomes from Plaquenil 15,275 users)

On Jul, 27, 2016

7,727 people who take Enbrel, Plaquenil are studied.


Number of reports submitted per year:

Enbrel and Plaquenil drug interactions.

Drug effectiveness over time:

Enbrel:
  • < 1 month: 42.0% - (3 of 7 people)
  • 1 - 6 months: 82.0% - (32 of 39 people)
  • 6 - 12 months: 80.0% - (8 of 10 people)
  • 1 - 2 years: 100.0% - (6 of 6 people)
  • 2 - 5 years: 46.0% - (7 of 15 people)
  • 5 - 10 years: 50.0% - (4 of 8 people)
  • 10+ years: 100.0% - (1 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Plaquenil:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 90.0% - (29 of 32 people)
  • 6 - 12 months: 42.0% - (3 of 7 people)
  • 1 - 2 years: 22.0% - (2 of 9 people)
  • 2 - 5 years: 16.0% - (4 of 25 people)
  • 5 - 10 years: 25.0% - (1 of 4 people)
  • 10+ years: 25.0% - (1 of 4 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Enbrel:
  • female: 59.0% - (31 of 52 people)
  • male: 88.0% - (30 of 34 people)
Plaquenil:
  • female: 25.0% - (12 of 48 people)
  • male: 84.0% - (28 of 33 people)

Drug effectiveness by age:

Enbrel:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 75.0% - (9 of 12 people)
  • 40-49: 58.0% - (10 of 17 people)
  • 50-59: 52.0% - (12 of 23 people)
  • 60+: 90.0% - (29 of 32 people)
Plaquenil:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 1 people)
  • 30-39: 36.0% - (4 of 11 people)
  • 40-49: 25.0% - (4 of 16 people)
  • 50-59: 23.0% - (5 of 21 people)
  • 60+: 84.0% - (27 of 32 people)

Most common drug interactions over time *:

< 1 month:
  • injection site erythema
  • rheumatoid arthritis
  • headache
  • hypersensitivity
  • asthenia
  • atrial septal defect
  • injection site pruritus
  • injection site reaction
  • neonatal aspiration
  • neonatal respiratory distress syndrome
1 - 6 months:
  • pain
  • drug ineffective
  • injection site erythema
  • injection site pruritus
  • rheumatoid arthritis
  • arthralgia
  • injection site pain
  • pneumonia
  • eczema
  • oedema peripheral
6 - 12 months:
  • pelvic pain
  • vaginal haemorrhage
  • pneumonia
  • rheumatoid arthritis
  • squamous cell carcinoma of the cervix
  • arthralgia
  • cellulitis
  • lung neoplasm
  • lymphadenopathy
  • nausea
1 - 2 years:
  • fatigue
  • rheumatoid arthritis
  • pneumonia
  • cellulitis
  • lung neoplasm
  • beta haemolytic streptococcal infection
  • coronary artery occlusion
  • escherichia infection
  • gastrointestinal disorder
  • lupus-like syndrome
2 - 5 years:
  • rheumatoid arthritis
  • hair loss
  • arthralgia
  • drug ineffective
  • bone and joint pain
  • pyrexia
  • fatigue
  • back pain
  • breast cancer
  • night sweats
5 - 10 years:
  • rheumatoid arthritis
  • fatigue
  • nausea
  • headache
  • dizziness
  • osteoporosis
  • arthralgia
  • arthropathy
  • fall
  • oedema peripheral
10+ years:
  • pneumonia
  • lung neoplasm
  • lymphadenopathy
  • appendicitis perforated
  • cellulitis
  • escherichia infection
  • ovarian cyst
  • pseudomonas infection
  • beta haemolytic streptococcal infection
  • arthralgia
not specified:
  • injection site pain
  • rheumatoid arthritis
  • injection site erythema
  • arthralgia
  • injection site haemorrhage
  • injection site swelling
  • nausea
  • injection site pruritus
  • fatigue
  • drug ineffective

Most common drug interactions by gender *:

female:
  • injection site pain
  • rheumatoid arthritis
  • injection site erythema
  • arthralgia
  • injection site haemorrhage
  • nausea
  • fatigue
  • injection site pruritus
  • drug ineffective
  • injection site swelling
male:
  • rheumatoid arthritis
  • arthralgia
  • pain
  • drug ineffective
  • injection site pain
  • pyrexia
  • cough
  • fatigue
  • nausea
  • injection site haemorrhage

Most common drug interactions by age *:

0-1:
  • bladder diverticulum
  • clostridial infection
  • palatal disorder
  • reflux nephropathy
  • renal hypertrophy
  • respiratory syncytial virus infection
  • urinary tract infection
  • congenital cystic kidney disease
  • chest pain
  • hypoaesthesia
2-9:
  • psoriasis
  • pyrexia
  • autoimmune hepatitis
  • cerebral oedema
  • chest pain
  • csf glucose decreased
  • dysarthria
  • injection site discolouration
  • injection site erythema
  • injection site pain
10-19:
  • injection site pain
  • injection site erythema
  • nausea
  • clostridial infection
  • hospitalisation
  • injection site pruritus
  • abdominal pain
  • drug ineffective
  • injection site haematoma
  • sickle cell anaemia
20-29:
  • vaginal haemorrhage
  • pelvic pain
  • injection site erythema
  • premature labour
  • anaesthetic complication pulmonary
  • injection site swelling
  • obstructed labour
  • respiratory arrest
  • uterine leiomyoma
  • squamous cell carcinoma of the cervix
30-39:
  • injection site erythema
  • injection site haemorrhage
  • injection site pruritus
  • injection site haematoma
  • rheumatoid arthritis
  • injection site swelling
  • nausea
  • injection site pain
  • cough
  • fatigue
40-49:
  • injection site erythema
  • rheumatoid arthritis
  • injection site haemorrhage
  • injection site pain
  • arthralgia
  • fatigue
  • headache
  • nausea
  • injection site swelling
  • drug ineffective
50-59:
  • injection site pain
  • rheumatoid arthritis
  • injection site erythema
  • injection site haemorrhage
  • arthralgia
  • oedema peripheral
  • nausea
  • fatigue
  • pain
  • pyrexia
60+:
  • rheumatoid arthritis
  • injection site pain
  • injection site haemorrhage
  • drug ineffective
  • arthralgia
  • pain
  • nausea
  • fatigue
  • injection site erythema
  • cough

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Enbrel and Plaquenil?

Can you answer these questions?

More questions for: Enbrel, Plaquenil

You may be interested in these reviews

More reviews for: Enbrel, Plaquenil

On eHealthMe, Enbrel (etanercept) is often used to treat rheumatoid arthritis. Plaquenil (hydroxychloroquine sulfate) is often used to treat rheumatoid arthritis. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.