Review: taking Excedrin and Promethazine with codeine together


Drug interactions are reported only by a few people who take Excedrin and Promethazine with codeine together. This review analyzes the effectiveness and drug interactions between Excedrin and Promethazine with codeine. It is created by eHealthMe based on reports of 2 people who take the same drugs from FDA and social media, and is updated regularly.

You are not alone

Join a support group for people who take Excedrin and Promethazine with codeine >>>

Personalized health information

On eHealthMe you can find out what patients like me (same gender, age) reported their drugs and conditions on FDA and social media since 1977. Our tools are free and anonymous. 86 million people have used us. 300+ peer-reviewed medical journals have referenced our original studies. Start now >>>


Excedrin has active ingredients of acetaminophen; aspirin; caffeine. It is often used in headache. (latest outcomes from Excedrin 7,575 users)

Promethazine With Codeine

Promethazine with codeine has active ingredients of codeine phosphate; promethazine hydrochloride. It is often used in cough. (latest outcomes from Promethazine with codeine 55 users)

On Jul, 29, 2016

2 people who take Excedrin, Promethazine With Codeine are studied.

Number of reports submitted per year:

Excedrin and Promethazine with codeine drug interactions.

Most common drug interactions over time *:

< 1 month:
  • haemolytic anaemia
not specified:
  • eye pain
  • vasodilatation

Most common drug interactions by gender *:

  • haemolytic anaemia
  • eye pain
  • vasodilatation

Most common drug interactions by age *:

  • haemolytic anaemia
  • eye pain
  • vasodilatation

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

Do you take Excedrin and Promethazine with codeine?

You may be interested in these reviews

More reviews for: Excedrin, Promethazine with codeine

On eHealthMe, Excedrin (acetaminophen; aspirin; caffeine) is often used to treat headache. Promethazine with codeine (codeine phosphate; promethazine hydrochloride) is often used to treat cough. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:

NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only, and has not been supported by scientific studies or clinical trials unless otherwise stated. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

You may report adverse side effects to the FDA at or 1-800-FDA-1088 (1-800-332-1088).

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.