Review: taking Fentanyl and Topiramate together


Summary

Drug interactions are reported among people who take Fentanyl and Topiramate together. This review analyzes the effectiveness and drug interactions between Fentanyl and Topiramate. It is created by eHealthMe based on reports of 400 people who take the same drugs from FDA and social media, and is updated regularly.

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Fentanyl

Fentanyl has active ingredients of fentanyl citrate. It is often used in pain. (latest outcomes from Fentanyl 36,850 users)

Topiramate

Topiramate has active ingredients of topiramate. It is often used in epilepsy. (latest outcomes from Topiramate 10,614 users)

On Aug, 24, 2016

400 people who take Fentanyl, Topiramate are studied.


Number of reports submitted per year:

Fentanyl and Topiramate drug interactions.

Drug effectiveness over time:

Fentanyl:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 50.0% - (1 of 2 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 0.0% - (0 of 0 people)
  • 5 - 10 years: 0.0% - (0 of 0 people)
  • 10+ years: 0.0% - (0 of 0 people)
  • not specified: 0.0% - (0 of 1 people)
Topiramate:
  • < 1 month: 0.0% - (0 of 0 people)
  • 1 - 6 months: 0.0% - (0 of 0 people)
  • 6 - 12 months: 0.0% - (0 of 0 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 0.0% - (0 of 1 people)
  • 5 - 10 years: 0.0% - (0 of 2 people)
  • 10+ years: 50.0% - (1 of 2 people)
  • not specified: 0.0% - (0 of 1 people)

Drug effectiveness by gender:

Fentanyl:
  • female: 20.0% - (1 of 5 people)
  • male: 0.0% - (0 of 1 people)
Topiramate:
  • female: 20.0% - (1 of 5 people)
  • male: 0.0% - (0 of 1 people)

Drug effectiveness by age:

Fentanyl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 3 people)
  • 50-59: 0.0% - (0 of 1 people)
  • 60+: 50.0% - (1 of 2 people)
Topiramate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 0.0% - (0 of 0 people)
  • 30-39: 0.0% - (0 of 0 people)
  • 40-49: 0.0% - (0 of 3 people)
  • 50-59: 100.0% - (1 of 1 people)
  • 60+: 0.0% - (0 of 2 people)

Most common drug interactions over time *:

< 1 month:
  • drug withdrawal syndrome
  • overdose
  • antibody test positive
  • completed suicide
  • fall
  • proteinuria
  • tooth loss
  • back pain
  • convulsion
  • dental caries
1 - 6 months:
  • emotional disorder
  • epilepsy
  • oligohydramnios
  • overdose
  • drug dependence
  • pain
  • convulsion
  • dental caries
  • dependence
  • depression
6 - 12 months:
  • calculus urethral
  • flank pain
  • obstruction gastric
  • pain
  • pancreatitis
  • pancreatitis acute
  • type 2 diabetes mellitus
  • urethral stenosis
  • weight increased
  • blister
1 - 2 years:
  • arthralgia
  • drug ineffective
  • drug withdrawal syndrome
  • blood urine present
  • completed suicide
  • dizziness
  • haematemesis
  • headache
  • insomnia
  • muscle spasms
2 - 5 years:
  • abnormal behaviour
  • dental caries
  • depression
  • drug dependence
  • dysarthria
  • tooth abscess
  • drug abuse
  • epilepsy
  • back injury
  • drug abuser
5 - 10 years:
  • abdominal distension
  • abdominal neoplasm
  • abdominal pain aggravated
  • anemia - b12 deficiency
  • anemia - hemolytic
  • bile duct pressure increased
  • bone and joint pain
  • fatigue
  • fecal incontinence
  • hair loss
10+ years:
  • breathlessness
  • contusion
  • convulsion
  • dizziness
  • fall
  • headache
  • loss of consciousness
  • loss of hair
  • memory impairment
  • pain
not specified:
  • pain
  • depression
  • nausea
  • drug ineffective
  • anxiety
  • vomiting
  • diarrhoea
  • arthralgia
  • serotonin syndrome
  • headache

Most common drug interactions by gender *:

female:
  • depression
  • pain
  • nausea
  • drug ineffective
  • vomiting
  • arthralgia
  • fall
  • serotonin syndrome
  • diarrhoea
  • anxiety
male:
  • pain
  • drug ineffective
  • drug withdrawal syndrome
  • suicidal ideation
  • drug dependence
  • pancreatitis
  • back pain
  • anxiety
  • dental caries
  • sedation

Most common drug interactions by age *:

2-9:
  • alanine aminotransferase increased
  • ammonia increased
  • aspartate aminotransferase increased
  • hepatotoxicity
  • hyperammonaemic encephalopathy
10-19:
  • renal tubular acidosis
  • tubulointerstitial nephritis
  • enteritis
  • nausea
  • neuralgia
  • abdominal pain upper
  • cholelithiasis
  • ewing's sarcoma recurrent
  • gallbladder injury
  • hypertension
20-29:
  • pulmonary embolism
  • nausea
  • vomiting
  • anxiety
  • emotional disorder
  • epilepsy
  • oligohydramnios
  • pain
  • abdominal pain lower
  • antibody test positive
30-39:
  • arthralgia
  • drug withdrawal syndrome
  • completed suicide
  • drug ineffective
  • respiratory arrest
  • cardiac arrest
  • pyrexia
  • vomiting
  • nephrolithiasis
  • pain
40-49:
  • serotonin syndrome
  • depression
  • pain
  • anxiety
  • fall
  • aphasia
  • diarrhoea
  • disturbance in attention
  • unresponsive to stimuli
  • arthralgia
50-59:
  • drug ineffective
  • pain
  • fatigue
  • nausea
  • vomiting
  • death
  • malaise
  • diarrhoea
  • paraesthesia
  • depression
60+:
  • flushing
  • anxiety
  • chest pain
  • diarrhoea
  • feeling abnormal
  • loss of consciousness
  • malaise
  • migraine
  • arthritis
  • tremor

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Fentanyl (fentanyl citrate) is often used to treat pain. Topiramate (topiramate) is often used to treat epilepsy. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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