Review: taking Fentanyl and Topiramate together


Summary

Drug interactions are reported among people who take Fentanyl and Topiramate together. This review analyzes the effectiveness and drug interactions between Fentanyl and Topiramate. It is created by eHealthMe based on reports of 734 people who take the same drugs from FDA and social media, and is updated regularly.

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Fentanyl

Fentanyl has active ingredients of fentanyl. It is often used in pain. (latest outcomes from Fentanyl 43,922 users)

Topiramate

Topiramate has active ingredients of topiramate. It is often used in epilepsy. (latest outcomes from Topiramate 8,543 users)

On Jul, 26, 2016

734 people who take Fentanyl, Topiramate are studied.


Number of reports submitted per year:

Fentanyl and Topiramate drug interactions.

Drug effectiveness over time:

Fentanyl:
  • < 1 month: 0.0% - (0 of 2 people)
  • 1 - 6 months: 25.0% - (2 of 8 people)
  • 6 - 12 months: 60.0% - (3 of 5 people)
  • 1 - 2 years: 0.0% - (0 of 1 people)
  • 2 - 5 years: 50.0% - (2 of 4 people)
  • 5 - 10 years: 0.0% - (0 of 1 people)
  • 10+ years: 0.0% - (0 of 1 people)
  • not specified: 0.0% - (0 of 0 people)
Topiramate:
  • < 1 month: 0.0% - (0 of 1 people)
  • 1 - 6 months: 0.0% - (0 of 1 people)
  • 6 - 12 months: 33.0% - (1 of 3 people)
  • 1 - 2 years: 0.0% - (0 of 0 people)
  • 2 - 5 years: 40.0% - (2 of 5 people)
  • 5 - 10 years: 37.0% - (3 of 8 people)
  • 10+ years: 66.0% - (2 of 3 people)
  • not specified: 0.0% - (0 of 0 people)

Drug effectiveness by gender:

Fentanyl:
  • female: 30.0% - (6 of 20 people)
  • male: 50.0% - (1 of 2 people)
Topiramate:
  • female: 36.0% - (7 of 19 people)
  • male: 50.0% - (1 of 2 people)

Drug effectiveness by age:

Fentanyl:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 50.0% - (2 of 4 people)
  • 40-49: 22.0% - (2 of 9 people)
  • 50-59: 25.0% - (1 of 4 people)
  • 60+: 33.0% - (1 of 3 people)
Topiramate:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 50.0% - (1 of 2 people)
  • 30-39: 50.0% - (2 of 4 people)
  • 40-49: 25.0% - (2 of 8 people)
  • 50-59: 75.0% - (3 of 4 people)
  • 60+: 0.0% - (0 of 3 people)

Most common drug interactions over time *:

< 1 month:
  • pain
  • feeling abnormal
  • drug ineffective
  • hallucination
  • completed suicide
  • fatigue
  • overdose
  • vomiting
  • agitation
  • confusional state
1 - 6 months:
  • drug dependence
  • depression
  • abnormal behaviour
  • dental caries
  • dysarthria
  • tooth abscess
  • drug abuse
  • pain
  • back injury
  • drug ineffective
6 - 12 months:
  • anxiety
  • fallot's tetralogy
  • mitral valve disease
  • premature baby
  • dizziness
  • overdose
  • altered visual depth perception
  • anger
  • arachnoiditis
  • back pain
1 - 2 years:
  • therapeutic response unexpected
  • adrenal insufficiency
  • abnormal behaviour
  • accidental death
  • back injury
  • blood pressure immeasurable
  • blood urine present
  • bronchopneumonia
  • cardiac hypertrophy
  • cardio-respiratory arrest
2 - 5 years:
  • pancreatitis
  • erythema
  • hypopnoea
  • infusion related reaction
  • drug withdrawal syndrome
  • abdominal pain upper
  • abnormal behaviour
  • achilles tendinitis
  • acidosis
  • acute respiratory distress syndrome
5 - 10 years:
  • anemia - b12 deficiency
  • anemia - hemolytic
  • bile duct pressure increased
  • bone and joint pain
  • fatigue
  • fecal incontinence
  • hair loss
  • abdominal distension
  • abdominal neoplasm
  • abdominal pain aggravated
10+ years:
  • complex regional pain syndrome
  • adverse event
  • benign intracranial hypertension
  • breathlessness
  • dizziness
  • drug ineffective
  • loss of hair
not specified:
  • pain
  • depression
  • drug ineffective
  • anxiety
  • headache
  • fall
  • nausea
  • arthralgia
  • weight decreased
  • withdrawal syndrome

Most common drug interactions by gender *:

female:
  • pain
  • depression
  • drug ineffective
  • headache
  • anxiety
  • fall
  • nausea
  • dizziness
  • weight decreased
  • malaise
male:
  • anxiety
  • neuralgia
  • tremor
  • withdrawal syndrome
  • depression
  • drug hypersensitivity
  • drug ineffective
  • pain
  • adverse drug reaction
  • joint injury

Most common drug interactions by age *:

2-9:
  • alanine aminotransferase increased
  • ammonia increased
  • aspartate aminotransferase increased
  • hepatotoxicity
  • hyperammonaemic encephalopathy
10-19:
  • renal tubular acidosis
  • tubulointerstitial nephritis
  • enteritis
  • neuralgia
  • pancreatitis
  • neoplasm malignant
  • ewing's sarcoma recurrent
  • hypertension
  • radiation injury
20-29:
  • anxiety
  • application site pain
  • arthralgia
  • bone infarction
  • depression
  • hypothyroidism
  • mood swings
  • suicidal ideation
  • abdominal pain lower
  • colitis
30-39:
  • drug ineffective
  • depression
  • pain
  • insomnia
  • arthralgia
  • weight decreased
  • vomiting
  • dizziness
  • drug withdrawal syndrome
  • pain in extremity
40-49:
  • depression
  • pain
  • anxiety
  • fall
  • constipation
  • drug ineffective
  • headache
  • nausea
  • diarrhoea
  • serotonin syndrome
50-59:
  • drug ineffective
  • pancreatitis
  • pain
  • erythema
  • infusion related reaction
  • weight decreased
  • nausea
  • hypopnoea
  • malaise
  • drug toxicity
60+:
  • tremor
  • withdrawal syndrome
  • adverse drug reaction
  • drug hypersensitivity
  • joint injury
  • neuralgia
  • staphylococcal infection
  • viral pericarditis
  • pneumonia
  • arthralgia

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Fentanyl (fentanyl) is often used to treat pain. Topiramate (topiramate) is often used to treat epilepsy. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

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