Review: taking Flexeril and Ativan together


Summary

Drug interactions are reported among people who take Flexeril and Ativan together. This review analyzes the effectiveness and drug interactions between Flexeril and Ativan. It is created by eHealthMe based on reports of 2,510 people who take the same drugs from FDA and social media, and is updated regularly.

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Flexeril

Flexeril has active ingredients of cyclobenzaprine hydrochloride. It is often used in muscle spasms. (latest outcomes from Flexeril 19,420 users)

Ativan

Ativan has active ingredients of lorazepam. It is often used in stress and anxiety. (latest outcomes from Ativan 38,886 users)

On Aug, 25, 2016

2,510 people who take Flexeril, Ativan are studied.


Number of reports submitted per year:

Flexeril and Ativan drug interactions.

Drug effectiveness over time:

Flexeril:
  • < 1 month: 8.0% - (2 of 24 people)
  • 1 - 6 months: 33.0% - (5 of 15 people)
  • 6 - 12 months: 9.0% - (1 of 11 people)
  • 1 - 2 years: 12.0% - (1 of 8 people)
  • 2 - 5 years: 50.0% - (7 of 14 people)
  • 5 - 10 years: 0.0% - (0 of 5 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 0.0% - (0 of 2 people)
Ativan:
  • < 1 month: 25.0% - (4 of 16 people)
  • 1 - 6 months: 15.0% - (3 of 19 people)
  • 6 - 12 months: 20.0% - (2 of 10 people)
  • 1 - 2 years: 35.0% - (5 of 14 people)
  • 2 - 5 years: 28.0% - (4 of 14 people)
  • 5 - 10 years: 61.0% - (8 of 13 people)
  • 10+ years: 62.0% - (5 of 8 people)
  • not specified: 0.0% - (0 of 2 people)

Drug effectiveness by gender:

Flexeril:
  • female: 28.0% - (19 of 67 people)
  • male: 10.0% - (2 of 20 people)
Ativan:
  • female: 34.0% - (26 of 75 people)
  • male: 23.0% - (5 of 21 people)

Drug effectiveness by age:

Flexeril:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 15.0% - (2 of 13 people)
  • 30-39: 28.0% - (7 of 25 people)
  • 40-49: 24.0% - (6 of 25 people)
  • 50-59: 25.0% - (3 of 12 people)
  • 60+: 25.0% - (3 of 12 people)
Ativan:
  • 0-1: 0.0% - (0 of 0 people)
  • 2-9: 0.0% - (0 of 0 people)
  • 10-19: 0.0% - (0 of 0 people)
  • 20-29: 28.0% - (4 of 14 people)
  • 30-39: 37.0% - (10 of 27 people)
  • 40-49: 39.0% - (11 of 28 people)
  • 50-59: 26.0% - (4 of 15 people)
  • 60+: 16.0% - (2 of 12 people)

Most common drug interactions over time *:

< 1 month:
  • confusional state
  • delirium
  • abnormal behaviour
  • anxiety
  • depression
  • respiratory failure
  • suicide attempt
  • unresponsive to stimuli
  • anaemia
  • pruritus
1 - 6 months:
  • haematemesis
  • pulmonary haemorrhage
  • cardiac arrest
  • adhd
  • anxiety
  • congenital cystic kidney disease
  • death
  • muscle spasms
  • panic attack
  • abnormal weight gain
6 - 12 months:
  • ammonia increased
  • confusion
  • depression
  • deep vein thrombosis
  • pulmonary embolism
  • anxiety
  • cancer in remission
  • cervical spinal stenosis
  • cervical spondylosis
  • completed suicide
1 - 2 years:
  • cardiac disorder
  • dyspnoea
  • nausea
  • stomach pain
  • anxiety
  • depression
  • dizziness
  • malaise
  • mental disorder
  • completed suicide
2 - 5 years:
  • circulatory collapse
  • coronary artery disease
  • emotional distress
  • gastrointestinal disorder
  • migraine
  • myocardial infarction
  • angiopathy
  • anxiety
  • dyspnoea exertional
  • femur fracture
5 - 10 years:
  • nausea and vomiting
  • abnormal behaviour
  • anxiety
  • compulsive shopping
  • depression
  • fatigue
  • fibromyalgia
  • heart pounding or racing
  • high blood cholesterol
  • high blood glucose level - infants
10+ years:
  • anxiety
  • depression
  • angular cheilitis
  • gum pain
  • hair loss
  • headache - migraine without aura
  • oral pain
  • pain - joints
  • pain - muscles
  • swallowing painful
not specified:
  • pain
  • anxiety
  • nausea
  • back pain
  • depression
  • fatigue
  • headache
  • dyspnoea
  • arthralgia
  • insomnia

Most common drug interactions by gender *:

female:
  • pain
  • anxiety
  • nausea
  • depression
  • fatigue
  • back pain
  • headache
  • dyspnoea
  • arthralgia
  • diarrhoea
male:
  • pain
  • anxiety
  • back pain
  • depression
  • nausea
  • insomnia
  • dyspnoea
  • asthenia
  • emotional distress
  • pain in extremity

Most common drug interactions by age *:

0-1:
  • congenital cystic kidney disease
  • diabetes mellitus
  • rhabdomyolysis
10-19:
  • thrombosis
  • anxiety
  • abdominal pain
  • alopecia
  • back pain
  • injury
  • myocardial infarction
  • alanine aminotransferase increased
  • blood testosterone decreased
  • cerebrovascular accident
20-29:
  • anxiety
  • vomiting
  • nausea
  • pain
  • insomnia
  • back pain
  • dyspnoea
  • injury
  • depression
  • pyrexia
30-39:
  • depression
  • anxiety
  • nausea
  • pain
  • headache
  • hypertension
  • asthenia
  • dyspnoea
  • back pain
  • arthralgia
40-49:
  • pain
  • anxiety
  • nausea
  • depression
  • fatigue
  • back pain
  • arthralgia
  • chest pain
  • asthenia
  • diarrhoea
50-59:
  • pain
  • anxiety
  • fatigue
  • headache
  • nausea
  • depression
  • back pain
  • dizziness
  • arthralgia
  • fall
60+:
  • pain
  • anxiety
  • back pain
  • nausea
  • dyspnoea
  • fall
  • weight decreased
  • anaemia
  • diarrhoea
  • pain in extremity

* Approximation only. Some reports may have incomplete information.

How to use the study: print a copy of the study and bring it to your health teams to ensure drug risks and benefits are fully discussed and understood.

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On eHealthMe, Flexeril (cyclobenzaprine hydrochloride) is often used to treat muscle spasms. Ativan (lorazepam) is often used to treat stress and anxiety. Find out below the conditions the drugs are used for and how effective they are.

What is the drug used for and how effecitve is it:


NOTE: The study is based on active ingredients and brand name. Other drugs that have the same active ingredients (e.g. generic drugs) are NOT considered.

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

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